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  • T64276Octanoyl coenzyme A lithium；化合物 Octanoyl coenzyme A lithiumOctanoyl coenzyme A lithium

    Octanoyl coenzyme A lithium is a derivative of the fatty acid acyl coenzyme A. Octanoyl coenzyme A lithium inhibits citrate synthase and glutamate dehydrogenase (IC50: 0.4-1.6 mM).

    价 格：￥电议型 号：T64276产 地：中国大陆

  • T64275Oblimersen；化合物 OblimersenOblimersen

    Oblimersen is a BCL-2 inhibitor targeting BCL-2 RNA. Oblimersen specifically binds to the first six codons of the BCL-2 mRNA sequence, thereby degrading BCL-2 mRNA and inducing apoptosis by down-regulating BCL-2 expression.

    价 格：￥电议型 号：T64275产 地：中国大陆

  • T64274Neuraminidase-IN-11；化合物 Neuraminidase-IN-11Neuraminidase-IN-11

    Neuraminidase-IN-11 (15e) is a selective and potent neuraminidase (NA) inhibitor that acts on the neuraminidase of H1N1 virus (IC50: 4.7 nM), H5N1 virus (IC50: 8.46 nM) and H5N8 virus (IC50: 1.5 nM).

    价 格：￥电议型 号：T64274产 地：中国大陆

  • T64273Nampt-IN-10 TFA；化合物 Nampt-IN-10 TFANampt-IN-10 TFA

    Nampt-IN-10 TFA (compound 4) is a phosphoribosyltransferase (NAMPT) inhibitor with cellular efficacy against A2780 (IC50: 5 nM) and CORL23 (IC50: 19 nM). The Nampt-IN-10 TFA can be used as a non-antimitotic payload for ADCs.

    价 格：￥电议型 号：T64273产 地：中国大陆

  • T64272MTL-CEBPA；化合物 MTL-CEBPAMTL-CEBPA

    MTL-CEPBA is a small activating RNA that targets C/EBPα upregulation and exhibits anti-inflammatory and anti-cancer effects.

    价 格：￥电议型 号：T64272产 地：中国大陆

  • T64271MAO-B-IN-6；化合物 MAO-B-IN-6MAO-B-IN-6

    MAO-B-IN-6 is a selective, potent, orally active MAO-B inhibitor (IC50: 0.019 μM). MAO-B-IN-6 is superior to Safinamide both in vitro and in vivo.

    价 格：￥电议型 号：T64271产 地：中国大陆

  • T64270Lutropin；化合物 LutropinLutropin

    Lutropin is a heterodimeric glycoprotein, a hormone produced by anterior pituitary gonadotrophs, which stimulates follicle development.

    价 格：￥电议型 号：T64270产 地：中国大陆

  • T6427Butein；紫铆因2’,3,4,4’-tetrahydroxy Chalcone；2’,3,4,4’-tetrahydroxy Chalcone|||紫铆因

    Butein (2’,3,4,4’-tetrahydroxy Chalcone), a plant polyphenol, is isolated from Rhus verniciflua. It can inhibit the activation of protein tyrosine kinase, NF-κB and STAT3, and also can inhibit EGFR.

    价 格：￥电议型 号：T6427产 地：中国大陆

  • T64269LP 12 hydrochloride hydrate；化合物 LP 12 hydrochloride hydrateLP 12 hydrochloride hydrate

    LP 12 hydrochloride hydrate is a selective and potent agonist at the 5-HT7 receptor (Ki: 0.13 nM). LP 12 hydrochloride hydrate is more selective for the 5-HT7 than the D2 receptor (Ki: 224 nM), 5-HT1A receptor (Ki: 60.9 nM) and 5-HT2A receptor (Ki: 60.9 nM). HT2A receptors (Ki>1000 nM).

    价 格：￥电议型 号：T64269产 地：中国大陆

  • T64268Liothyronine sodium hydrate；化合物 Liothyronine sodium hydrateLiothyronine sodium hydrate

    Liothyronine sodium hydrate is a potent thyroid hormone. liothyronine sodium hydrate is also a potent agonist of TRα and TRβ, acting on hTRα (IC50: 2.33 nM) and hTRβ (IC50: 2.33 nM).

    价 格：￥电议型 号：T64268产 地：中国大陆

  • T64267Laropiprant sodium；化合物 Laropiprant sodiumLaropiprant sodium

    Laropiprant sodium is a potent and selective DP receptor antagonist with Ki values of 0.57 nM for TP receptors and 2.95 nM for DP receptors.

    价 格：￥电议型 号：T64267产 地：中国大陆

  • T64266KR-39038；化合物 KR-39038KR-39038

    KR-39038 is an orally active GRK5 (G protein-coupled receptor kinase 5) inhibitor (IC50: 0.02 μM). KR-39038 inhibits the HDAC5 pathway in neonatal cardiomyocytes and significantly inhibits angiotensin II-induced hypertrophy, resulting in significant anti-myocardial hypertrophy and improved cardiac function. KR-39038 can be used to conduct heart failure studies.

    价 格：￥电议型 号：T64266产 地：中国大陆

  • T64265JAK1/TYK2-IN-3；化合物 JAK1/TYK2-IN-3JAK1/TYK2-IN-3

    JAK1/TYK2-IN-3 is a selective, potent, orally active dual inhibitor of TYK2 (IC50: 6 nM) and JAK1 (IC50: 37 nM).JAK1/TYK2-IN-3 selectively acts on both JAK2 and JAK3 with IC50 values of 140 nM and 362 nM.JAK1/TYK2 -IN-3 regulates the expression of TYK2/JAK1-related genes and the formation of Th1, Th2 and Th17 cells to exert its anti-inflammatory activity.

    价 格：￥电议型 号：T64265产 地：中国大陆

  • T64264ISIS 104838；化合物 ISIS 104838ISIS 104838

    ISIS 104838 is an antisense oligonucleotide that inhibits the production of tumour necrosis factor (TNF-alpha), which causes pain and swelling in rheumatoid arthritis joints.

    价 格：￥电议型 号：T64264产 地：中国大陆

  • T64263HSP90-IN-9；化合物 HSP90-IN-9HSP90-IN-9

    HSP90-IN-9 is a selective and potent HSP90 inhibitor.HSP90-IN-9 exhibits a dose-dependent fungicidal effect.HSP90-IN-9 in combination with FLC inhibits fungal biofilm formation and fungal morphological changes.HSP90-IN-9 downregulates ERG11, CDR1 and CDR2 gene expression and restores resistance to FLC. HSP90-IN-9 downregulates ERG11, CDR1 and CDR2 gene expression and restores FLC resistance.

    价 格：￥电议型 号：T64263产 地：中国大陆

  • T64262Heparin Lithium salt；化合物 Heparin Lithium saltHeparin Lithium salt

    Heparin Lithium salt is an anticoagulant that reversibly binds antithrombin III (ATIII). Heparin Lithium salt markedly blocks exosome-cell interactions.

    价 格：￥电议型 号：T64262产 地：中国大陆

  • T64261HDAC/HSP90-IN-4；化合物 HDAC/HSP90-IN-4HDAC/HSP90-IN-4

    HDAC/HSP90-IN-4 significantly inhibited HDAC and HSP90 activity, with compound 20 (HDACIC50= 194 nM; HSP90αIC50= 153 nM) and compound 26 ((HDACIC50= 360 nM; HSP90αIC50= 77 nM) having the strongest HDAC and HSP90α inhibition. effect. Both compounds induced HSP90 expression and down-regulated HSP90 client proteins, which play an important role in the regulation of cancer cell survival and invasion.

    价 格：￥电议型 号：T64261产 地：中国大陆

  • T64260HBV-IN-20；化合物 HBV-IN-20HBV-IN-20

    HBV-IN-20 is a potent, orally active HBV inhibitor (EC50: 0.46 μM). HBV-IN-20 is a classical type II CpAM (core protein assembly regulator).

    价 格：￥电议型 号：T64260产 地：中国大陆

  • T6426Buclizine dihydrochloride；盐酸安其敏Longifene|||Buclina|||Buclizine HCl|||UCB-4445；盐酸安其敏|||Longifene|||Bu

    Buclizine dihydrochloride (Buclina) is the hydrochloride salt form of buclizine, a piperazine histamine H1 receptor antagonist with primarily antiemetic and antivertigo activities. Buclizine dihydrochloride binds to and blocks the histamine H1 receptor, thereby preventing the symptoms that are caused by histamine activity. Buclizine dihydrochloride exerts its anti-emetic effect by binding to and blocking the muscarinic and histamine receptors in the vomiting center of the central nervous system

    价 格：￥电议型 号：T6426产 地：中国大陆

  • T64259GLS1 Inhibitor-5；化合物 GLS1 Inhibitor-5GLS1 Inhibitor-5

    GLS1 Inhibitor-5 (compound 24y) is a selective, orally active inhibitor of glutaminase 1 (GLS1) (IC50: 68 nM). gLS1 Inhibitor-5 induces apoptosis and exhibits anti-tumour effects.

    价 格：￥电议型 号：T64259产 地：中国大陆

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