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T78097Mazdutide；化合物 MazdutideIBI-362|||LY-3305677|||OXM-3；IBI-362|||LY-3305677|||OXM-3
Mazdutide (IBI-362; LY-3305677), a synthetic oxyntomodulin analog, serves as a glucagon-like peptide-1 (GLP-1R)/glucagon receptor (GCGR) co-agonist. Demonstrating safety and tolerability, Mazdutide is utilized in obesity and type 2 diabetes (T2D) research [1] [2].
价 格：￥电议型 号：T78097产 地：中国大陆
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T77985AZD9496 deacrylic acid phenol；化合物 AZD9496 deacrylic acid phenolAZD9496 deacrylic acid phenol
AZD9496 deacrylic acid phenol (AZD9496) represents a portion of the ligand that targets the protein for PROTAC ER Degrader-4 [1].
价 格：￥电议型 号：T77985产 地：中国大陆
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T7699AZD7325；化合物AZD-7325AZD-7325；AZD-7325
AZD7325 (AZD-7325) is a GABA-Aα2,3 -selective receptor modulator.
价 格：￥电议型 号：T7699产 地：中国大陆
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T7681AZD-5069；化合物AZD-5069AZD-5069
AZD-5069 is an chemokine receptor 2 antagonist (CXCR2; IC50 = 0.79 nM).
价 格：￥电议型 号：T7681产 地：中国大陆
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T7587LTenapanor HCl；化合物 T7587LRDX-5791|||AZD 1722|||AZD-1722|||AZD1722|||RDX5791|||RDX 5791；RDX-5791|||AZD
Tenapanor( AZD-1722, RDX 5791) is an inhibitor of the sodium-proton (Na(+)/H(+)) exchanger NHE3, which is used for sodium handling in the gastrointestinal tract and kidney.
价 格：￥电议型 号：T7587L产 地：中国大陆
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T7587Tenapanor；化合物TenapanorRDX-5791|||RDX 5791|||AZD 1722|||Tenapanor free base|||RDX5791|||AZD-1722|||AZ
Tenapanor (RDX 5791) is an inhibitor of the sodium-proton (Na(+)/H(+)) exchanger NHE3, which plays a prominent role in sodium handling in the gastrointestinal tract and kidney. Tenapanor possesses an excellent preclinical safety profile and, as of now, there are no serious concerns about its side effects.
价 格：￥电议型 号：T7587产 地：中国大陆
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T74395Dicloromezotiaz；化合物 DicloromezotiazDicloromezotiaz
Dicloromezotiaz, a potent insecticide, targets nicotinic acetylcholine receptors (nAChRs) to control a broad spectrum of lepidoptera [1].
价 格：￥电议型 号：T74395产 地：中国大陆
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T74143AZD4694 Precursor；化合物 AZD4694 PrecursorAZD4694 Precursor
AZD4694 Precursor (AZ13040214) serves as the foundational compound for synthesizing [18F]AZD4694, a high-affinity amyloid-β imaging ligand targeting amyloid-β plaques [1].
价 格：￥电议型 号：T74143产 地：中国大陆
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T72515Elobixibat hydrate；化合物 Elobixibat hydrateA 3309 hydrate ; AZD 7806 hydrate|||AZD 7806 hydrate|||A 3
Elobixibat hydrate, a potent inhibitor of the ileal bile acid transporter (IBAT), exhibits IC50 values of 0.53 ± 0.17 nM, 0.13 ± 0.03 nM, and 5.8 ± 1.6 nM for human, mouse, and canine IBAT, respectively. It is utilized in the research of chronic idiopathic constipation (CIC).
价 格：￥电议型 号：T72515产 地：中国大陆
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T72215Lesogaberan hydrochloride；Lesogaberan hydrochlorideAZD-3355 hydrochloride；AZD-3355 hydrochloride
Lesogaberan (AZD-3355) hydrochloride is a potent and selective GABA B receptor agonist with an EC 50 of 8.6 nM for human recombinant GABA B receptor. The affinity ( K i s) of Lesogaberan hydrochloride for rat GABA B and GABA A receptors, as measured by displacement of [ 3 H]GABA binding in brain membranes: 5.1 nM and 1.4 μM, respectively. Lesogaberan hydrochloride inhibits transient lower esophageal sphincter relaxation through a peripheral mode of action [1] .
价 格：￥电议型 号：T72215产 地：中国大陆
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T71894AZD3229 Tosylate；化合物 AZD3229 TosylateAZD3229 Tosylate
AZD3229 Tosylate is a highly potent inhibitor targeting mutant forms of the pan-KIT enzyme, with a primary application in the treatment of gastrointestinal stromal tumors (GISTs).
价 格：￥电议型 号：T71894产 地：中国大陆
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T71484Utatrectinib；化合物 AZD7451AZD-7451；AZD-7451
Utatrectinib (AZD-7451) is a potent, orally active, and selective inhibitor of Trk. It effectively inhibits TrkC activation and the associated tumorigenic behaviors.
价 格：￥电议型 号：T71484产 地：中国大陆
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T71423AZD5213；化合物 AZD-5213AZD5213
AZD5213 is a selective, competitive antagonist of the human H3 receptor, exhibiting a pK i of 9.3 against hH3R. It is utilized in the research of sleep and cognitive regulation.
价 格：￥电议型 号：T71423产 地：中国大陆
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T7136AZD-6280；化合物AZD6280AZD-6280
AZD6280 is a novel, subtype-selective GABAAα2/3 receptor positive modulators, used for treatment of generalized anxiety disorder.
价 格：￥电议型 号：T7136产 地：中国大陆
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T71357AZD-3783；化合物 AZD-3783AZD-3783
AZD-3783 is a selective 5-hydroxytryptamine 1B receptor antagonist with probable antidepressant and anxiolytic activity.
价 格：￥电议型 号：T71357产 地：中国大陆
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T71262AZD-8418；化合物 AZD-8418AZD-8418
AZD-8418 is an mGlu2 receptor positive allosteric modulators that attenuates nicotine-taking and nicotine-seeking behavior. Acute treatment with AZD8418 (0.37, 1.12, 3.73, 7.46, and 14.92 mg/kg) and AZD8529 (1.75, 5.83, 17.5, and 58.3 mg/kg) deceased nicotine self-administration and had no effect on food-maintained responding. Chronic treatment with AZD8418 attenuated nicotine self-administration, but tolerance to this effect developed quickly. The inhibition of nicotine self-administration by c
价 格：￥电议型 号：T71262产 地：中国大陆
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T71255AZD-8055 fumarate；化合物 AZD-8055 fumarateAZD-8055 fumarate
AZD-8055 fumarate is a potent, selective, and orally bioavailable ATP-competitive mammalian target of rapamycin kinase inhibitor with in vitro and in vivo antitumor activity.
价 格：￥电议型 号：T71255产 地：中国大陆
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T71242AZD-1897；化合物 AZD-1897AZD-1897
AZD-1897 is an ATP-competitive pan-PIM inhibitor. When combined with the Akt inhibitor AZD5363, AML cells from putative leukaemia stem cells incur a reduction in levels of the anti-apoptotic protein MCL1. The combination of PIM and Akt inhibition holds promise for the treatment of AML.
价 格：￥电议型 号：T71242产 地：中国大陆
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T7122AZD-7648；化合物AZD-7648AZD-7648
AZD-7648 is an inhibitor of DNA-dependent protein kinase (DNA-PK) with the IC50 of 0.63 nM in an enzyme assay,has anti-tumor activity.
价 格：￥电议型 号：T7122产 地：中国大陆
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T71129AZD6564；化合物 AZD6564AZD6564
AZD6564 is a fibrinolysis inhibitor which acts via interference of a protein-?protein interaction.
价 格：￥电议型 号：T71129产 地：中国大陆
