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T61673Anticancer agent 56;化合物 Anticancer agent 56Anticancer agent 56
Anticancer agent 56 (compound 4d) is a powerful anti-cancer compound with favorable drug-like properties. It shows significant anticancer activity against multiple cancer cell lines, with an IC50 value of less than 3 μM. Anticancer agent 56 exerts its effects by causing cell cycle arrest at the G2/M phase and activating the mitochondrial apoptosis pathway. Mechanistically, it induces the accumulation of reactive oxygen species (ROS), upregulates BAX, downregulates Bcl-2, and triggers the activat
价 格:¥电议型 号:T61673产 地:中国大陆
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T61602Anticancer agent 35;化合物 Anticancer agent 35Anticancer agent 35
Anticancer agent 35 (compound 10), a sulfonylurea derivative, is a potent anticancer agent. Anticancer agent 35 inhibits A549, A431, PACA2 cell growth with IC 50 s of 18.1 μg/mL, 4.0 μg/mL, 18.9 μg/mL, respectively [1].
价 格:¥电议型 号:T61602产 地:中国大陆
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T61582Anticancer agent 57;化合物 Anticancer agent 57Anticancer agent 57
Anticancer agent 57 (compound 14) demonstrates potent inhibition of MDA-MB-231, MDA-MB-468, and MCF-7 cell lines, with IC 50 values ranging from 6.43 to 8.00 μM. Additionally, this agent induces cell cycle arrest and promotes apoptosis. In vivo studies using nude mice xenografted with MADMB-231 cells have shown that Anticancer agent 57 effectively inhibits tumor growth. Consequently, Anticancer agent 57 can serve as a valuable tool for researching triple negative breast cancer (TNBC) [1].
价 格:¥电议型 号:T61582产 地:中国大陆
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T61576Anticancer agent 83;化合物 Anticancer agent 83Anticancer agent 83
Anticancer Agent 83, a potent inhibitor of LOX IMVI cell growth, demonstrates anticancer efficacy with a GI50 value of 0.15 mM. It disrupts mitochondrial membrane potential and induces DNA damage, thereby promoting apoptosis in leukemia cells [1].
价 格:¥电议型 号:T61576产 地:中国大陆
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T61461Anticancer agent 37;化合物 Anticancer agent 37Anticancer agent 37
Anticancer agent 37 (compound 18) is a sulfonylurea derivative known for its potent anticancer activity. It efficiently inhibits the growth of HePG2 cells, displaying an IC 50 value of 17.2 μg/mL [1].
价 格:¥电议型 号:T61461产 地:中国大陆
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T61412Anticancer agent 47;化合物 Anticancer agent 47Anticancer agent 47
Anticancer agent 47 (compound 4j) exhibits potent anticancer properties, demonstrating antiproliferative activities and inducing apoptosis as well as cell cycle arrest at G0/G1 phase. Moreover, Anticancer agent 47 has exhibited significant in vivo antitumor activities [1].
价 格:¥电议型 号:T61412产 地:中国大陆
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T61379Anticancer agent 30;化合物 Anticancer agent 30Anticancer agent 30
Anticancer agent 30 (compound 6f-Z) is a potent anticancer compound. It belongs to the class of 3-arylidene-2-oxindole derivatives and acts as a selective inhibitor of CDK2. Extensive research has demonstrated its significant anticancer activity, making it a promising candidate for cancer treatment [1].
价 格:¥电议型 号:T61379产 地:中国大陆
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T61378Anticancer agent 29;化合物 Anticancer agent 29Anticancer agent 29
Anticancer agent 29 (Compd E/Z-6f) exhibits potent anticancer activity, as indicated by IC50 values of 0.054 μM, 0.127 μM, 0.129 μM, and 0.396 μM for CDK2, CDK1, CDK4, and CDK6, respectively [1].
价 格:¥电议型 号:T61378产 地:中国大陆
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T61230Anticancer agent 74;化合物 Anticancer agent 74Anticancer agent 74
Anticancer agent 74 exhibits moderate anticancer activity with lower selectivity and cytotoxicity compared to doxorubicin towards normal cells [1].
价 格:¥电议型 号:T61230产 地:中国大陆
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T61097Anticancer agent 70;化合物 Anticancer agent 70Anticancer agent 70
Anticancer agent 70 (Compound 21) is a potent anticancer compound that demonstrates remarkable cytotoxicity against multiple human cancer cell lines. It induces G0/G1-cell cycle arrest and concurrently elevates the levels of p53 and p21 proteins. Furthermore, Anticancer agent 70 induces ATP depletion and disruption of the mitochondrial membrane potential [1].
价 格:¥电议型 号:T61097产 地:中国大陆
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T61046Anticancer agent 43;抗癌剂43Anticancer agent 43
Anticancer agent 43 is a potent anticancer agent that induces apoptosis through caspase 3, PARP1, and Bax protein-dependent pathways.Anticancer agent 43 induces DNA damage and can be used in the study of glioblastoma in rats.
价 格:¥电议型 号:T61046产 地:中国大陆
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T60998Anticancer agent 75;化合物 Anticancer agent 75Anticancer agent 75
Anticancer agent 75 has good antiplasmodial activity. Anticancer agent 75 is a potent anticancer agent with cytotoxicity and selectivity in cancer cell lines. The cytotoxicity of Anticancer agent 75 to normal human kidney cell lines is at least 35 times lower than that of the Doxorubicin standard [1].
价 格:¥电议型 号:T60998产 地:中国大陆
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T60852Anticancer agent 46;抗癌剂46Anticancer agent 46
Anticancer agent 46 is a potent anti-cancer agent, showing anti-proliferative activity in cellular assays, with an IC50 of 0.986 μM against MGC803 cells.
价 格:¥电议型 号:T60852产 地:中国大陆
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T60776Anticancer agent 68;化合物 Anticancer agent 68Anticancer agent 68
Compound 12, also known as Anticancer agent 68, functions as an anti-cancer agent by arresting cells at the G2/M phase and inducing programmed cell death. Moreover, it promotes tumor suppression by activating p53 and PTEN [1].
价 格:¥电议型 号:T60776产 地:中国大陆
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T60420Anticancer agent 73;抗癌剂73Anticancer agent 73
Anticancer agent 73 is an anticancer agent which potently targets transactivation response(TAR) RNA-binding protein 2 (TRBP) and disrupts the TRBP-Dicer interaction. Anticancer agent 73 suppresses the growth and metastasis of HCC in vitro and in vivo by modulating expression profiles of miRNAome and proteome in HCC cells.
价 格:¥电议型 号:T60420产 地:中国大陆
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T40479Anticancer agent 13;Anticancer agent 13Anticancer agent 13
Anticancer agent 13 is an anticancer agent from dicarboxylic acids and amines.
价 格:¥电议型 号:T40479产 地:中国大陆
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T40330Anticancer agent 15;Anticancer agent 15Anticancer agent 15
Anticancer agent 15, an anticancer agent, exerts its efficacy by elevating intracellular levels of reactive oxygen species (ROS) and inducing cell death in melanoma cancer cells through necroptosis.
价 格:¥电议型 号:T40330产 地:中国大陆
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T39868Anticancer agent 11;Anticancer agent 11Anticancer agent 11
Anticancer agent 11 an effective broad-spectrum anticancer agent, exerts its therapeutic potential by suppressing angiogenesis and facilitating the formation of DNA cross-links.
价 格:¥电议型 号:T39868产 地:中国大陆
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T39501Anticancer agent 7;Anticancer agent 7Anticancer agent 7
Anticancer agent 7 (Example 5) is an anti-cancer agent that exhibits potent anticancer activity against H1650 lung cancer cells, with an IC50 value of 5 μM.
价 格:¥电议型 号:T39501产 地:中国大陆
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T27998MDK-4204;化合物 T27998Anticancer AgentI|||MDK 4204|||Anticancer Agent I|||MDK4204|||Anticancer Agent-I;
MDK-4204, an anticancer agent, shows significant anti-cancer activity with IC50 values of 8.8 ?M and 9.5 ?M in PC-3 and DU-145 cells, respectively.
价 格:¥电议型 号:T27998产 地:中国大陆