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T80147EcAMP3;化合物 EcAMP3EcAMP3
EcAMP3, a hairpin-like peptide, exhibits both antifungal and antibacterial properties. It belongs to the EcAMP precursor family characterized by seven identical cysteine motifs: C1XXXC2(11–13)C3XXXC4 [1].
价 格:¥电议型 号:T80147产 地:中国大陆
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T798839-Chloromethyl-10-hydroxy-11-F-Camptothecin;化合物 9-Chloromethyl-10-hydroxy-11-F-Camptothecin9-Chlorom
9-Chloromethyl-10-hydroxy-11-F-Camptothecin, a novel derivative of camptothecin, functions as a DNA topoisomerase I (Topo I) inhibitor with potential applications in anticancer research [1].
价 格:¥电议型 号:T79883产 地:中国大陆
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T79718CaMKIIα-PHOTAC;化合物 CaMKIIα-PHOTACCaMKIIα-PHOTAC
CaMKIIα-PHOTAC is a photochemically targeted chimera (PHOTAC) that specifically targets Ca2+/calmodulin-dependent protein kinase II α (CaMKIIα). This molecule facilitates the ubiquitination and subsequent proteasome-mediated degradation of CaMKIIα when exposed to certain light wavelengths. Under illumination, CaMKIIα-PHOTAC diminishes synaptic functions and weakens evoked field excitatory postsynaptic potentials in the mouse hippocampus, thus impacting physiological responses. Additionally, it i
价 格:¥电议型 号:T79718产 地:中国大陆
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T79707Cholicamideβ;化合物 CholicamideβCholicamideβ
Cholicamideβ (compound 6), a self-assembling small molecule cancer vaccine adjuvant, forms low cytotoxicity virus-like particles and upon binding to peptide antigens, enhances dendritic cell-mediated antigen presentation and induces antigen-specific T-cell responses, with the ability to induce apoptosis and necrosis [1].
价 格:¥电议型 号:T79707产 地:中国大陆
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T7959(+)-ISOPINOCAMPHEOL;(1S,2S,3S,5R)-(+)-异松蒎醇(+)-ISOPINOCAMPHEOL
(+)-ISOPINOCAMPHEOL is a natural product.
价 格:¥电议型 号:T7959产 地:中国大陆
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T778207-Aminomethyl-10-methyl-11-fluoro camptothecin;化合物 7-Aminomethyl-10-methyl-11-fluoro camptothecin7-A
7-Aminomethyl-10-methyl-11-fluoro camptothecin, serving as a cytotoxic component of the antibody-drug conjugate (ADC) MC-AAA-NHCH2OCH2COO-7-aminomethyl-10-methyl-11-fluoro camptothecin, is employed in the synthesis of camptothecin ADCs [1].
价 格:¥电议型 号:T77820产 地:中国大陆
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T7780Blarcamesine;化合物AVex-73AE-37|||AVex-73;AE-37|||AVex-73
Blarcamesine (AVex-73) is a muscarinic M1 agonist potentially for the treatment of Alzheimer´s disease.
价 格:¥电议型 号:T7780产 地:中国大陆
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T77701FL118;化合物FL118FL 118|||FL-118|||10,11-(Methylenedioxy)-20(S)-camptothecin;FL 118|||FL-118|||10,11-(M
FL118 is a novel survivin inhibitor that inhibits cancer stem cell-like properties.FL118 is a novel camptothecin analog with anticancer activity that inhibits epithelial-mesenchymal transition through the Wnt/β-catenin signaling pathway, thereby inhibiting migration and invasion of human breast cancer cells.
价 格:¥电议型 号:T77701产 地:中国大陆
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T77064Licaminlimab;化合物 LicaminlimabLicaminlimab
Licaminlimab (OCS-02) is a single-chain anti-TNF alpha antibody fragment that targets TNF alpha, an inflammatory cytokine produced by macrophages and monocytes during inflammation [1].
价 格:¥电议型 号:T77064产 地:中国大陆
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T76938Camoteskimab;化合物 CamoteskimabCamoteskimab
Camoteskimab (AVTX-007), a fully human, high-affinity anti-IL-18 monoclonal antibody, holds promise for research into autoinflammatory diseases, such as adult-onset Still’s disease (AOSD) [1].
价 格:¥电议型 号:T76938产 地:中国大陆
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T76770Camidanlumab;化合物 CamidanlumabCamidanlumab
Camidanlumab (HuMax-TAC), a CD25 monoclonal antibody, selectively binds to the cell-surface antigen CD25, prevalent on numerous hematological tumors but minimally present on normal tissues. This specificity facilitates its use in developing antibody-drug conjugates (ADCs) aimed at treating diseases such as lymphoma and leukemia [1].
价 格:¥电议型 号:T76770产 地:中国大陆
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T76690Mavrilimumab;玛弗利木单抗CAM 3001;CAM 3001
Mavrilimumab (CAM 3001) is a monoclonal antibody with antiviral activity that has an affinity for the α subunit of the granulocytic-macrophage colony-stimulating factor (GM-CSF) receptor and blocks downstream intracellular signaling of GM-CSF. GM-CSF may be associated with an overactive inflammatory response associated with respiratory failure and death, and could be used to study rheumatoid arthritis.
价 格:¥电议型 号:T76690产 地:中国大陆
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T76408Autocamtide-3;化合物 Autocamtide-3Autocamtide-3
Autocamtide-3, a selective substrate for CaMKII (Ca2+/calmodulin-dependent kinase II) (CaMK), comprises a 13-amino-acid peptide featuring Thr287 [1].
价 格:¥电议型 号:T76408产 地:中国大陆
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T75737Autocamtide-2-related inhibitory peptide, myristoylated TFA;化合物 Autocamtide-2-related inhibitory pep
Myristoylated Autocamtide-2-related inhibitory peptide, trifluoroacetic acid (TFA) form, is a potent and highly specific inhibitor of CaMKII, exhibiting an IC50 of 40 nM [1]. This compound constitutes the myristoylated variant of Autocamtide-2-related inhibitory peptide.
价 格:¥电议型 号:T75737产 地:中国大陆
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T75736Autocamtide-2-related inhibitory peptide TFA;化合物 Autocamtide-2-related inhibitory peptide TFAAutocam
Autocamtide-2-related inhibitory peptide (TFA) acts as a highly specific and potent CaMKII inhibitor, exhibiting an IC50 value of 40 nM.
价 格:¥电议型 号:T75736产 地:中国大陆
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T75725Camstatin TFA;化合物 Camstatin TFACamstatin TFA
Camstatin TFA, a 25-residue fragment derived from the IQ motif of PEP-19, effectively binds to calmodulin and inhibits neuronal nitric oxide (NO) synthase, demonstrating its functional activity [1].
价 格:¥电议型 号:T75725产 地:中国大陆
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T75134MC-GGFG-AM-(10Me-11F-Camptothecin);化合物 MC-GGFG-AM-(10Me-11F-Camptothecin)MC-GGFG-AM-(10Me-11F-Campto
MC-GGFG-AM-(10Me-11F-Camptothecin) acts as a linker-payload conjugate in the synthesis of ZW251, an antibody-drug conjugate (ADC) designed to target human GPC3. This ADC comprises a humanized IgG1 antibody attached to ZD06519, a novel camptothecin-based topoisomerase 1 inhibitor, through a maleimide-anchor and a cleavable glycyl glycyl phenylalanyl glycine (GGFG)-aminomethyl (AM) linker. ZW251 exhibits strong affinity for GPC3 in both human and cynomolgus monkey cells. It is characterized by rap
价 格:¥电议型 号:T75134产 地:中国大陆
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T74654-Methylbenzylidene camphor;4-甲基苄亚基樟脑Enzacamene|||4-MBC;Enzacamene|||4-甲基苄亚基樟脑|||3-(4-甲基苯亚甲基)樟脑|||4-
4-Methylbenzylidene camphor is an ultraviolet light blocker used in cosmetics and sunscreen preparations ,specifically UV B radiation, also has estrogenic activities.
价 格:¥电议型 号:T7465产 地:中国大陆
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T73718MDCG sodium;化合物 MDCG sodiumNOX 100 sodium|||N-methyl-N-dithiocarboxyglucamine sodium;NOX 100 sodium|
MDCG sodium (N-methyl-N-dithiocarboxyglucamine sodium) is a metal chelator that promotes biliary excretion of Cd.
价 格:¥电议型 号:T73718产 地:中国大陆
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T73708Sp-cAMPS triethylamine;化合物 Sp-cAMPS triethylamineSp-cAMPS triethylamine
Sp-cAMPS triethylamine, a cAMP analog, serves as a potent activator of cAMP-dependent PKA I and II and acts as a competitive inhibitor of phosphodiesterase (PDE3A) with a K i of 47.6 ?M. Additionally, it binds the PDE10 GAF domain with an EC 50 of 40 μM [1] [2] [3].
价 格:¥电议型 号:T73708产 地:中国大陆