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  • T20793Magnesium Lithospermate B;丹参酸 B 镁Monomethyl lithospermate B|||Lithospermate B;丹參酸B鎂|||Monomethyl lit

    Magnesium Lithospermate B is a natural product activates eNOS and ameliorates endothelial dysfunction in diabetes by enhancing vasodilation in addition to reducing oxidative stress, it can protecte cardiomyocytes from ischemic injury through specific inhibition of TAB1-p38 apoptosis signaling.improves renal failure.

    价 格:¥电议型 号:T20793产 地:中国大陆

  • T20574Magnesium lactate;化合物 T20574Bis(lactato)magnesium;Bis(lactato)magnesium

    Magnesium lactate is a magnesium donor and buffering agent.

    价 格:¥电议型 号:T20574产 地:中国大陆

  • T1945GNE-7915;化合物GNE7915GNE7915;GNE7915

    GNE-7915 is a highly potent, selective and brain-penetrable leucine-rich repeat kinase 2 (LRRK2) inhibitor.

    价 格:¥电议型 号:T1945产 地:中国大陆

  • T19389L-Ascorbic acid 2-phosphate magnesium;维生素C磷酸酯镁2-Phospho-L-ascorbic acid magnesium;2-Phospho-L-ascorb

    L-Ascorbic acid 2-phosphate magnesium (2-Phospho-L-ascorbic acid magnesium) acts as an antioxidant and a stimulator of hepatocyte growth factor (HGF) production.It is a long-acting vitamin C derivative that can stimulate collagen formation and expression.

    价 格:¥电议型 号:T19389产 地:中国大陆

  • T19281LDihydroxyacetone phosphate hemimagnesium hydrate;二羟丙酮磷酸半镁盐水合物DHAP Mg|||Dihydroxyacetone phosphate he

    Dihydroxyacetone phosphate hemimagnesium salt hydrate is also known as dihydroxyacetone phosphate or 3-hydroxy-2-oxopropyl phosphate. Dihydroxyacetone phosphate hemimagnesium salt hydrate is found in all organisms from bacteria to humans. In humans, Dihydroxyacetone phosphate hemimagnesium salt hydrate is involved in many enzymatic reactions. Dihydroxyacetone phosphate hemimagnesium salt hydrate has been studied for the treatment of lymphoma, large cell lymphoma, and diffuse lymphoma.

    价 格:¥电议型 号:T19281L产 地:中国大陆

  • T1916Apitolisib;化合物ApitolisibRG 7422|||GNE 390|||GDC-0980;RG 7422|||GNE 390|||GDC-0980

    Apitolisib (RG 7422), an effective, class I PI3K inhibitor for PI3Kα(IC50=5 nM), PI3Kβ(IC50=27 nM), PI3Kδ(IC50=7 nM), PI3Kγ (IC50=14 nM), is used in trials study of solid cancers, breast cancer, prostate cancer, renal cell carcinoma, and endometrial carcinoma, among others.

    价 格:¥电议型 号:T1916产 地:中国大陆

  • T1770GNE-9605;化合物GNE9605GNE-9605

    GNE-9605 is a highly effective, specifical, and brain-penetrant LRRK2 inhibitor (IC50: 19 nM).

    价 格:¥电议型 号:T1770产 地:中国大陆

  • T16574Pregnenolone monosulfate sodium salt;化合物 T165743β-Hydroxy-5-pregnen-20-one monosulfate sodium salt;3

    Pregnenolone monosulfate sodium salt is a powerful neurosteroid, the main precursor of various steroid hormones including steroid ketones. Pregnenolone monosulfate sodium salt can protect the brain from cannabis intoxication. Pregnenolone monosulfate sodium salt acts as a signaling-specific inhibitor of the cannabinoid CB1 receptor. Pregnenolone monosulfate sodium salt also inhibits the effects of tetrahydrocannabinol (THC) that are mediated by the CB1 receptors.

    价 格:¥电议型 号:T16574产 地:中国大陆

  • T16429GNE 2861;化合物GNE 2861GNE 2861

    GNE 2861 inhibits PAK4, PAK5, and PAK6 (IC50s: 7.5, 36, 126 nM, respectively). GNE 2861 is a PAK inhibitor that shows group II selectivity.

    价 格:¥电议型 号:T16429产 地:中国大陆

  • T15408GNE 5729;化合物 T15408GNE 5729

    GNE 5729 is an NMDAR of brain permeable positive allosteric modulator (EC50: 37 nM for GluN2A; 4.7 and 9.5 μM for GluN2C and GluN2D, respectively).

    价 格:¥电议型 号:T15408产 地:中国大陆

  • T15407GNE-0723;化合物 T15407GNE-0723

    GNE 0723 is an NMDAR brain permeable positive allosteric modulator (EC50: 21 nM for GluN2A; 7.4 and 6.2 μM for GluN2C and GluN2D, respectively).

    价 格:¥电议型 号:T15407产 地:中国大陆

  • T15406GNE-955;化合物 T15406GNE-955

    GNE-955 is a potent and orally active inhibitor of pan Pim kinase (Kis: 0.018, 0.11, 0.08 nM for Pim1, Pim2, Pim3, respectively).

    价 格:¥电议型 号:T15406产 地:中国大陆

  • T15405GNE-781;GNE-781GNE-781

    GNE-781 is a highly potent and selective inhibitor of CBP (IC50: 0.94 nM in TR-FRET assay). GNE-781 also inhibits BRET and BRD4(1) (IC50s: 6.2 nM and 5100 nM, respectively).

    价 格:¥电议型 号:T15405产 地:中国大陆

  • T15404GNE-6468;化合物 T15404GNE-6468

    GNE-6468 is a potent and selective agonist of RORγ(RORc) (EC50: 13 nM for HEK-293 cell).

    价 格:¥电议型 号:T15404产 地:中国大陆

  • T15403GNE-618;化合物 T15403GNE-618

    GNE-618 is a potent and orally active inhibitor of nicotinamide phosphoribosyltransferase (IC50: 6 nM). GNE-618 depletes NAD levels and induces tumor cell death. It has anti-tumor activity.

    价 格:¥电议型 号:T15403产 地:中国大陆

  • T15402GNE-4997;化合物 T15402GNE-4997

    GNE-4997 is a potent and selective inhibitor of the interleukin-2-inducible T-cell kinase (Ki: 0.09 nM). The correlation between the basicity of solubilizing elements in GNE-4997 and off-target antiproliferative effects decreases cytotoxicity.

    价 格:¥电议型 号:T15402产 地:中国大陆

  • T15400GNE-272;化合物 T15400GNE-272

    GNE-272 is a selective inhibitor of CBP/EP300 (IC50: 0.02, 0.03, and 13 μM for CBP, EP300, and BRD4, respectively) and a selective in vivo probe for CBP/EP300.

    价 格:¥电议型 号:T15400产 地:中国大陆

  • T15399GNE-207;化合物 T15399GNE-207

    GNE-207 is a selective and orally bioavailable inhibitor of the bromodomain of CBP (IC50: 1 nM). It has a selective index of >2500-fold against BRD4 (1). GNE-207 displays excellent CBP potency (EC50: 18 nM for MYC expression in MV-4-11 cells).

    价 格:¥电议型 号:T15399产 地:中国大陆

  • T15398GNE-0946;化合物 T15398GNE-0946

    GNE-0946 is a potent and selective agonist of RORγ (EC50: 4 nM for HEK-293 cell).

    价 格:¥电议型 号:T15398产 地:中国大陆

  • T15397GNE-049;化合物 T15397GNE-049

    GNE-049 is a highly potent and selective inhibitor of CBP (IC50: 1.1 nM in TR-FRET assay). GNE-049 also inhibits BRET and BRD4(1) (IC50s: 12 nM and 4200 nM, respectively).

    价 格:¥电议型 号:T15397产 地:中国大陆

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