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T69203HMR1031;化合物 HMR1031HMR1031
HMR1031 is a potent and specific integrin α4?1 or very late antigen 4 (VLA-4) receptor antagonist which binds to vascular cell adhesion molecule-1 (VCAM-1) and fibronectin.
价 格:¥电议型 号:T69203产 地:中国大陆
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T6918Olmutinib;奥莫替尼HM61713, BI 1482694|||BI 1482694|||HM61713;HM61713, BI 1482694|||奥莫替尼|||BI 1482694|||H
Olmutinib (HM61713, BI 1482694) is an orally available small molecule, a mutant-selective inhibitor of epidermal growth factor receptor (EGFR) with potential antineoplastic activity. Olmutinib binds to and inhibits mutant forms of EGFR, thereby leading to cell death of EGFR-expressing tumor cells. As this agent is selective towards mutant forms of EGFR, its toxicity profile may be reduced as compared to non-selective EGFR inhibitors which also inhibit the EGFR wild-type form.
价 格:¥电议型 号:T6918产 地:中国大陆
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T6837Flavopiridol;夫拉平度L868275|||Alvocidib|||NSC 649890 HCl|||HMR-1275;L868275|||Alvocidib|||夫拉平度|||NSC 64
Flavopiridol (Alvocidib) (Alvocidib) competes with ATP to inhibit CDKs including CDK1, CDK2, CDK4 and CDK6 with IC50 of ~ 40 nM. It is 7.5-fold more selective for CDK1, 2, 4, 6 versus CDK7. Flavopiridol is initially found to inhibit EGFR and PKA. Phase 1/2.
价 格:¥电议型 号:T6837产 地:中国大陆
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T67879hMAO-B-IN-5;化合物hMAO-B-IN-5hMAO-B-IN-5
hMAO-B-IN-5 is a potent reversible and selective human monoamine oxidase hMAO-B inhibitor (IC50:0.12μM). hMAO-B-IN-5 can cross the blood-brain barrier and can be used in the study of Parkinson´s disease. It is a promising compound in the treatment and diagnosis of central nervous system diseases.
价 格:¥电议型 号:T67879产 地:中国大陆
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T67764hMAO-B-IN-4;化合物hMAO-B-IN-4hMAO-B-IN-4
hMAO-B-IN-4 is a selective, reversible and blood–brain barrier (BBB) penetrable inhibitor of human monoamine oxidase-B (hMAO-B, IC50=0.067 μM, Ki= 0.03 μM, hMAO-A, IC50= 33.82 μM).
价 格:¥电议型 号:T67764产 地:中国大陆
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T66793MC-Val-Ala-OH;化合物 MC-Val-Ala-OHMC-Val-Ala-OH
(S)-2-((S)-2-(6-(2, 5-Dioxo-2H-pyrrol-1(5H)-yl)hexanamido)-3-methylbutanamido)propanoic acid is a linker for antibody-drug-conjugation (ADC).
价 格:¥电议型 号:T66793产 地:中国大陆
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T66613Fmoc-N(Hmb)-Gly-OH;化合物 Fmoc-N(Hmb)-Gly-OHFmoc-N(Hmb)-Gly-OH
Fmoc-N(Hmb)-Gly-OH is a useful organic compound for research related to life sciences. The catalog number is T66613 and the CAS number is 148515-78-0.
价 格:¥电议型 号:T66613产 地:中国大陆
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T66103MOC-Val-OH;化合物 MOC-Val-OHMOC-Val-OH
MOC-Val-OH is a useful organic compound for research related to life sciences. The catalog number is T66103 and the CAS number is 74761-42-5.
价 格:¥电议型 号:T66103产 地:中国大陆
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T6364Desfesoterodine;(R)-5-羟甲基托特罗定5-HMT|||(R)-5-Hydroxymethyl Tolterodine|||PNU-200577|||5-HM|||5-hydroxy
Desfesoterodine (5-HMT) is a new muscarinic receptor antagonist with Kb of 0.84 nM.
价 格:¥电议型 号:T6364产 地:中国大陆
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T6333MM-102;化合物MM-102MM102|||HMTase Inhibitor IX;MM102|||HMTase Inhibitor IX
MM-102 (HMTase Inhibitor IX) is a high-affinity peptidomimetic MLL1 inhibitor with IC50 of 0.4 μM.
价 格:¥电议型 号:T6333产 地:中国大陆
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T63281Antileishmanial agent-11;化合物 Antileishmanial agent-11Antileishmanial agent-11
Antileishmanial agent-11 is a potent antileishmanial agent that acts on Leishmania brazilensis (IC50: 28.3 μM), Leishmania infantum (IC50: 24.8 μM) and T. cruzi (IC50: 13.0 μM) with outstanding antiprotozoal effect.
价 格:¥电议型 号:T63281产 地:中国大陆
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T63076IHMT-TRK-284;化合物 IHMT-TRK-284IHMT-TRK-284
IHMT-TRK-284 (Compound 34) is a potent, orally active type II TRK kinase inhibitor that acts on TRKA (IC50: 10.5 nM), TRKB (IC50: 0.7 nM), and TRKC (IC50: 2.6 nM). IHMT-TRK-284 exhibits good selectivity in the kinase group and has good anti-tumour effects in vivo.
价 格:¥电议型 号:T63076产 地:中国大陆
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T62574Antileishmanial agent-6;化合物 Antileishmanial agent-6Antileishmanial agent-6
Antileishmanial agent-6 is a potent anti-leishmanial agent with anti-leishmanial activity (IC50: 0.54 μM) and cytotoxicity (IC50: 10.2 μM) against Leishmania donovani and L-6.
价 格:¥电议型 号:T62574产 地:中国大陆
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T62512IHMT-MST1-58;化合物IHMT-MST1-58IHMT-MST1-58
IHMT-MST1-58 is a STE20-like protein 1 kinase (MST1) inhibitor (IC50:23 nM) with high efficiency, selectivity and oral activity. IHMT-MST1-58 can be used to study type 1 or type 2 diabetes.
价 格:¥电议型 号:T62512产 地:中国大陆
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T62404SHMT-IN-2;化合物SHMT-IN-2SHMT-IN-2
SHMT-IN-2 (compound 2) is a specific human SHMT1/2 small molecule inhibitor that acts on SHMT1 (IC50: 13 nM) and SHMT2 (IC50: 66 nM). SHMT-IN-2 inhibits the growth of many human cancer cells and is sensitive to B-cell lymphoma.
价 格:¥电议型 号:T62404产 地:中国大陆
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T62330Antileishmanial agent-12;化合物 Antileishmanial agent-12Antileishmanial agent-12
Antileishmanial agent-12 (compound 5a) is a potent anti-leishmanial agent with antibacterial activity against Leishmania brazilensis (IC50: 14.9 μM), Leishmania infantum (IC50: 21.3 μM) and T. cruzi (IC50. 9.3 μM). 9.3 μM) had antiprotozoal effects.
价 格:¥电议型 号:T62330产 地:中国大陆
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T62210Antileishmanial agent-10;化合物 Antileishmanial agent-10Antileishmanial agent-10
Antileishmanial agent-10 (Compound 7h) is an antiprotozoal agent.
价 格:¥电议型 号:T62210产 地:中国大陆
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T61971CHMFL-PI4K-127;化合物 CHMFL-PI4K-127CHMFL-PI4K-127
CHMFL-PI4K-127 (compound 15g) is a highly selective inhibitor of PfPI4K (Plasmodium falciparum PI4K kinase) with oral activity (IC50=0.9 nM). CHMFL-PI4K-127 shows strong inhibitory activity against Plasmodium falciparum 3D7 (EC50=25.1 nM). CHMFL-PI4K-127 has anti-malaria effect.
价 格:¥电议型 号:T61971产 地:中国大陆
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T61710Antileishmanial agent-7;化合物 Antileishmanial agent-7Antileishmanial agent-7
Antileishmanial agent-7 (compound 23) exhibits strong antileishmanial activity against Leishmania donovani and L-6, with IC50 values of 6.89 and 259 μM, respectively [1].
价 格:¥电议型 号:T61710产 地:中国大陆
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T61560Antileishmanial agent-5;化合物 Antileishmanial agent-5Antileishmanial agent-5
Antileishmanial agent-4 is a ribonucleoside analogue with potent activity against L.infantum and T.cruzi, having EC 50 values of 0.68 μM and 0.83 μM, respectively [1].
价 格:¥电议型 号:T61560产 地:中国大陆