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T79449Antileishmanial agent-19；化合物 Antileishmanial agent-19Antileishmanial agent-19
Compound F27 (Antileishmanial agent-19) is an antileishmanial compound effective against L. donovani promastigotes, demonstrating an IC50 of 3.39 μM. It functions by inhibiting the Leishmania prolyl-tRNA synthetase and disrupting the host PI3K/Akt/CREB axis-mediated IL-10 secretion. Additionally, Compound F27 promotes autophagy-mediated apoptosis in L. donovani promastigotes and has been shown to reduce parasite burden in L.d-infected animals [1].
价 格：￥电议型 号：T79449产 地：中国大陆
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T79419Antileishmanial agent-24；化合物 Antileishmanial agent-24Antileishmanial agent-24
Antileishmanial agent-24 (compound 33) exhibits antileishmanial activity, demonstrating an inhibitory concentration 50 (IC50) value of 5.39 μM against amastigotes [1].
价 格：￥电议型 号：T79419产 地：中国大陆
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T79390Antileishmanial agent-23；化合物 Antileishmanial agent-23Antileishmanial agent-23
Antileishmanial agent-23 (compound G1/9), a potent and selective trypanothione reductase (TR) inhibitor, exhibits an IC50 of 2.24 ± 0.52 μM. It effectively inhibits the growth of Leishmania, Trypanosoma cruzi, and Trypanosoma brucei [1].
价 格：￥电议型 号：T79390产 地：中国大陆
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T78964Antileishmanial agent-17；化合物 Antileishmanial agent-17Antileishmanial agent-17
Antileishmanial agent-17, a coumarin hybrid, exhibits potent antileishmanial activity (IC50 <0.78 μM) while proving non-toxic to normal VERO cells. It specifically interacts with the folate pathway enzymes pteridine reductase and DHFR-TS. Efficacy against the promastigote form is highlighted by an IC50 value of 0.40 μM, and against the amastigote form, an IC50 of 0.68 μM, respectively.
价 格：￥电议型 号：T78964产 地：中国大陆
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T78963Antileishmanial agent-16；化合物 Antileishmanial agent-16Antileishmanial agent-16
Antileishmanial agent-16 (compound 14c), an anti-Leishmania agent, exhibits potent activity against Leishmania major promastigotes (IC50 = 0.59 ?M) and amastigotes (IC50 = 0.81 ?M), while maintaining a favorable safety profile in mammalian cells (VERO cells) [1].
价 格：￥电议型 号：T78963产 地：中国大陆
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T78962Antileishmanial agent-15；化合物 Antileishmanial agent-15Antileishmanial agent-15
Antileishmanial agent-15 (compound 13c) exhibits potent activity against L. major promastigotes and amastigotes, demonstrating IC50 values of 0.78 μM for promastigotes and 0.99 μM for amastigotes, while also showing cytotoxicity at these concentrations [1].
价 格：￥电议型 号：T78962产 地：中国大陆
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T78680Antileishmanial agent-14；化合物 Antileishmanial agent-14Antileishmanial agent-14
Antileishmanial agent-14, a sulfuretin analog, exhibits potential activity against Leishmania donovani promastigotes (IC 50 = 4.1 μM) and inhibits infection by L. donovani amastigotes (IC 50 = 11.1 μM) [1].
价 格：￥电议型 号：T78680产 地：中国大陆
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T785472-Phenyl-2-(2-pyridyl)acetonitrile；化合物 2-Phenyl-2-(2-pyridyl)acetonitrileα-Phenyl-2-pyridineacetonit
2-Phenyl-2-(2-pyridyl)acetonitrile represents the principal metabolite of the antigastric agent SC 15396, produced by the supernatant fraction of rat liver homogenate; SC 15396 functions to inhibit gastric secretion [1].
价 格：￥电议型 号：T78547产 地：中国大陆
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T776856-Bromo-4-methoxypyrazolo[1,5-a]pyridine-3-carbonitrile；6-溴-4-甲氧基吡唑并[1,5-a]吡啶-3-甲腈6-Bromo-4-methoxyp
6-Bromo-4-methoxypyrazolo[1,5-a]pyridine-3-carbonitrile is a PDK1 inhibitor with anticancer and antiproliferative activity that can be used to study angiosarcoma, adenocarcinoma, multiple myeloma, psoriasis, prostate cancer, and Alzheimer´s disease.
价 格：￥电议型 号：T77685产 地：中国大陆
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T76730Uliledlimab；化合物 UliledlimabUliledlimab
Uliledlimab, a humanized monoclonal antibody, exhibits potent activity against CD73, inhibiting the conversion of extracellular adenosine monophosphate (AMP) to adenosine. It holds potential for use in cancer research [1].
价 格：￥电议型 号：T76730产 地：中国大陆
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T76634(Sar1,Ile4,8)-Angiotensin II；化合物 (Sar1,Ile4,8)-Angiotensin II(Sar1,Ile4,8)-Angiotensin II
(Sar1,Ile4,8)-Angiotensin II is a functionally selective agonist for the angiotensin II type 1 receptor (AT1R), enhancing insulin-stimulated signaling of the insulin receptor (IR) and glycogen synthesis. It boosts the insulin-induced phosphorylation of Akt and GSK3α/β [1].
价 格：￥电议型 号：T76634产 地：中国大陆
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T76624(Ile8)-Oxytocin；化合物 (Ile8)-Oxytocin(Ile8)-Oxytocin
(Ile8)-Oxytocin is a neurohypophysial hormone mesotocin produced in marsupials [1] .
价 格：￥电议型 号：T76624产 地：中国大陆
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T76583H-Ile-Lys-Val-Ala-Val-OH；化合物 H-Ile-Lys-Val-Ala-Val-OHH-Ile-Lys-Val-Ala-Val-OH
H-Ile-Lys-Val-Ala-Val-OH, a significant active site within laminin-1, enhances cell adhesion, neurite outgrowth, and tumor growth. It also encourages the growth and proliferation of BMMSC populations through the activation of MAPK/ERK1/2 and PI3K/Akt signaling pathways [1] [2].
价 格：￥电议型 号：T76583产 地：中国大陆
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T7644DPN；2,3-双(4-羟苯基)丙腈Diarylpropionitrile；Diarylpropionitrile|||2,3-双(4-羟苯基)丙腈
DPN (Diarylpropionitrile) is an selective agonist of estrogen receptor β (ERβ) .
价 格：￥电议型 号：T7644产 地：中国大陆
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T76289EILEVPST；化合物 EILEVPSTEILEVPST
EILEVPST, a recombinant human fibronectin-derived low-molecular-weight peptide fragment, promotes cell type-specific α4 integrin-mediated adhesion. It is utilized in thrombogenesis research [1].
价 格：￥电议型 号：T76289产 地：中国大陆
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T76217Ac-Val-Gln-aIle-Val-aTyr-Lys-NH2；化合物 Ac-Val-Gln-aIle-Val-aTyr-Lys-NH2Ac-Val-Gln-aIle-Val-aTyr-Lys-NH
Ac-Val-Gln-aIle-Val-aTyr-Lys-NH2 demonstrates serum stability and non-toxicity to neuronal cells, while selectively inhibiting the fibrilization of tau in preference to Aβ 42.
价 格：￥电议型 号：T76217产 地：中国大陆
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T75841Ac-Tyr(PO3H2)-Glu-Glu-Ile-Glu-OH TFA；化合物 Ac-Tyr(PO3H2)-Glu-Glu-Ile-Glu-OH TFAAc-Tyr(PO3H2)-Glu-Glu-I
Ac-Tyr(PO3H2)-Glu-Glu-Ile-Glu-OH TFA (compound 1) serves as a high-affinity pentapeptide that binds to the src SH2 domain with an IC 50 value of approximately 1 ?M. Additionally, it acts as an inhibitor of src SH3-SH2: phosphoprotein interactions [1].
价 格：￥电议型 号：T75841产 地：中国大陆
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T7575L1[Sar1, Ile8]-Angiotensin II acetate；化合物[Sar1, Ile8]-Angiotensin II acetate[Sar1, Ile8]-Angiotensin I
[Sar1, Ile8]-Angiotensin II acetate activates both the NADPH and NADH oxidases, and stimulates superoxide anion formation in vascular smooth muscle cells. [Sar1, Ile8]-Angiotensin II acetate has multiple effects on vascular smooth muscle, including contra
价 格：￥电议型 号：T7575L1产 地：中国大陆
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T7575L[Sar1, Ile8]-Angiotensin II 3TFA；化合物[Sar1, Ile8]-Angiotensin II 3TFA[Sar1, Ile8]-Angiotensin II 3TFA
[Sar1, Ile8]-Angiotensin II 3TFA ([Sar1, Ile8]-Angiotensin II 3TFA (37827-06-8(free base))) is a peptide that has multiple effects on vascular smooth muscle.
价 格：￥电议型 号：T7575L产 地：中国大陆
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T7575[Sar1, Ile8]-Angiotensin II；化合物[Sar1, Ile8]-Angiotensin II(3TFA)[Sar1, Ile8]-Angiotensin II(3TFA)；[S
[Sar1, Ile8]-Angiotensin II(3TFA) is a peptide that has multiple effects on vascular smooth muscle.
价 格：￥电议型 号：T7575产 地：中国大陆
