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T36051Lipoxin A4;脂氧素 A4LXA4;脂氧素 A4|||LXA4
Lipoxin A4 (LXA4) is a trihydroxy fatty acid containing a conjugated tetraene, produced by the metabolism of (±)15-HETE or 15-HpETE with human leukocytes.[1] LXA4 is equipotent to leukotriene B4 in inducing superoxide generation in human neutrophils at 0.1 μM.2 LXA4 is associated with several other biological functions including leukocyte activation, chemotaxis effects, natural killer cell inhibition, and monocyte migration and adhesion.[2],[3],[4] Analytical and biological comparisons of synth
价 格:¥电议型 号:T36051产 地:中国大陆
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T3579PLX8394;化合物PLX8394PLX8394
PLX8394 is an orally active inhibitor of serine/threonine-protein kinase B-Raf (BRAF) protein. PLX8394 can selectively bind to and inhibit the activity of both wild-type and mutated forms of BRAF, then inhibit the proliferation of tumor cells which express mutated forms of BRAF. PLX8394 appears to be effective against tumors that express multiple mutated forms of the kinase and may be an effective therapeutic agent for tumors that are resistant to other BRAF inhibitor therapies that are specific
价 格:¥电议型 号:T3579产 地:中国大陆
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T3547Sotagliflozin;化合物SotagliflozinLX-4211|||LP-802034;LX-4211|||LP-802034
Sotagliflozin (LP-802034) is an orally bioavailable inhibitor of the sodium-glucose co-transporter subtype 1 (SGLT1) and 2 (SGLT2), with potential antihyperglycemic activity.
价 格:¥电议型 号:T3547产 地:中国大陆
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T35343MTI-31;化合物MTI-31MTI-31|||LXI-15029;MTI-31|||LXI-15029
MTI-31 (LXI-15029) is a potent, orally active and highly selective inhibitor of mTORC1 and mTORC2. MTI-31 is selective for mTOR (Kd: 0.20 nM) versus PIK3CA, PIK3CB and PIK3G with >5,000 fold selectivity in mTOR binding assays. MTI-31 shows an IC50 of 39 nM for mTOR in LANCE assay of mTOR substrate phosphorylation with 100 μM ATP[1].
价 格:¥电议型 号:T35343产 地:中国大陆
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T35337TeduglutideTeduglutideALX-0600|||Revestive|||TAK 633|||Gattex
Teduglutide (ALX-0600, Gattex, Revestive, TAK 633)是人胰高血糖素样肽-2 (GLP-2)的类似物,可与GLP-2 receptors 结合。Teduglutide 在动物模型中可延长 GLP-2 的肠道营养特性。
价 格:¥电议型 号:T35337产 地:中国大陆
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T3450LX4211 N-4 Intermediate 9化合物 T3450索格列净中间体9|||Sotagliflozin Intermediate 9
LX4211 N-4 Intermediate 9 is an intermediate of Sotagliflozin, which is an orally bioavailable inhibitor of SGLT1 and SGLT2.
价 格:¥电议型 号:T3450产 地:中国大陆
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T32985LX-7101 hydrochloride;化合物 T32985LX-7101 hydrochloride
LX-7101 hydrochloride is a bioactive chemical.
价 格:¥电议型 号:T32985产 地:中国大陆
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T32984LX-201 cation;化合物 T32984LX-201 cation
LX-201 cation is a bioactive chemical.
价 格:¥电议型 号:T32984产 地:中国大陆
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T31916Gaxilose;化合物 T319164-Galactosylxylose|||4-O-Galactosyl-D-xylose|||4-O-Galactosylxylose;4-Galactosylx
Gaxilose, also known as 4-Galactosylxylose, a synthetic disaccharide and a substrate of intestinal lactase. Gaxilose is used in a new noninvasive diagnostic test based on urine or serum measurement of D-xylose after lactase cleavage of orally administered 4-galactosylxylose (gaxilose). Gaxilose is hydrolyzed into galactose and xylose in vivo. Galactose is converted into glucose in the liver and xylose is absorbed from a passive way and partially metabolized endogenously (50%). The rest appears i
价 格:¥电议型 号:T31916产 地:中国大陆
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T31616ELX-02;化合物 T31616NB-124|||NB 124|||NB124|||ELX02|||ELX 02;NB-124|||NB 124|||NB124|||ELX02|||ELX 02
ELX-02, also known as NB-124, is a eukaryotic ribosomal selective glycoside (ERSG) designed to increase the read-through activity in patients with nonsense mutations and enable the production of sufficient amounts of full-length functional protein to restore activity.
价 格:¥电议型 号:T31616产 地:中国大陆
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T31479Diisopropyl xanthogen disulfide;二硫化二异丙基黄原酸酯NSC1339|||NSC 1339|||Isopropylxanthic disulfide|||NSC-133
Diisopropyl xanthogen disulfide (NSC-1339) can be used to synthesize a proligand for metal complexes related to the molybdenum cofactor.
价 格:¥电议型 号:T31479产 地:中国大陆
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T30771CC-15262;化合物 T30771UNII-8H195P4LXF|||Pomalidomide metabolite M10|||CC15262;UNII-8H195P4LXF|||Pomalid
CC-15262 is a bio-active chemical.
价 格:¥电议型 号:T30771产 地:中国大陆
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T30251AZD-1305;化合物AZD-1305UNII-CZO834LXQM|||AZD 1305;UNII-CZO834LXQM|||AZD 1305
AZD-1305 is a novel anti-arrhythmic compound that primarily blocks the fast component of IKr, l-type calcium currents and intra-ward sodium currents in mammalian cells and ventricular cardiomyocytes and can be used in studies to reverse arrhythmias.
价 格:¥电议型 号:T30251产 地:中国大陆
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T27866LXY6090;化合物 T27866LXY 6090|||LXY-6090;LXY 6090|||LXY-6090
LXY6090 is a HIF-1 inhibitor. LXY6090 inhibited the activity of HIF-1 and downregulated the protein level of HIF-1α in breast cancer cells. LXY6090 showed in vivo anticancer efficacy by decreasing the HIF-1α expression in nude mice bearing MX-1 tumor xenografts.
价 格:¥电议型 号:T27866产 地:中国大陆
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T27865LX-6171;化合物LX-6171LX6171;LX6171
LX-6171, a proline transporter (SLC6A7) inhibitor, is used potentially for the treatment of schizophrenia and Alzheimer´s disease.
价 格:¥电议型 号:T27865产 地:中国大陆
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T27864LX-2931;化合物LX-2931LX 3305|||LX2931|||LX-3305|||ACB20034|||LX 2931|||LX3305;LX 3305|||LX2931|||LX-330
LX-2931(LX-3305) is a sphingosine-1-phosphate cleavage enzyme (S1P) inhibitor for the treatment of rheumatoid arthritis.
价 格:¥电议型 号:T27864产 地:中国大陆
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T27720KD-027;化合物 T27720KD 027|||SLx-2101|||SLx2101|||KD027|||SLx 2101;KD 027|||SLx-2101|||SLx2101|||KD027|
KD-027, a PDE5A inhibitor, is used potentially for the treatment of hypertension.
价 格:¥电议型 号:T27720产 地:中国大陆
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T27719KD-026;化合物KD-026SLx 4090|||SLx4090|||KD026|||SLx-4090;SLx 4090|||SLx4090|||KD026|||SLx-4090
KD-026 (SLx 4090), a microsomal triglyceride transfer protein (MTP) inhibitor(IC50 = 8.0 nM), is used in type 2 diabetes studies.
价 格:¥电议型 号:T27719产 地:中国大陆
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T27133DCLX069;化合物DCLX069DCLX 069|||DCLX-069;DCLX 069|||DCLX-069
DCLX069 is a selective protein arginine methyltransferase 1 (PRMT1) inhibitor with an IC50 value of 17.9 ?M. DCLX069 occupies the SAM binding pocket to exert the inhibitory effect. DCLX069 effectively blocks cell proliferation in breast cancer, liver cancer, and acute myeloid leukemia cell lines.
价 格:¥电议型 号:T27133产 地:中国大陆
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T270768-Cyclopentyl-1,3-dimethylxanthineA1受体拮抗剂,CPTCPT|||A1受体拮抗剂,CPT
8-Cyclopentyl-1,3-dimethylxanthine (CPT)?is a potent antagonist of adenosine A1 receptor.
价 格:¥电议型 号:T27076产 地:中国大陆