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T13133Tetrabenazine MetaboliteTetrabenazine Metabolite
Tetrabenazine Metabolite is an active Tetrabenazine metabolite. Tetrabenazine Metabolite is a inhibitor of vesicular monoamine transporter 2 (VMAT2) (Ki=13.4 nM).
价 格:¥电议型 号:T13133产 地:中国大陆
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T6435CCT129202inhibit,CCT-129202,CCT 129202,Inhibitor,CCT129202,Aurora Kinase
CCT129202 is an ATP-competitive pan-Aurora inhibitor for Aurora A, Aurora B and Aurora C with IC50 of 0.042 μM, 0.198 μM and 0.227 μM, respectively. It is less potent to FGFR3, GSK3β, PDGFRβ, etc.
价 格:¥电议型 号:T6435产 地:中国大陆
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TN2296Vinaginsenoside R4Vinaginsenoside R 4,Vinaginsenoside R4,inhibit,Vinaginsenoside R-4,Inhibitor
Vinaginsenoside R4 has melanogenic inhibitory activity, it may have potential as a new skin whitening compound.
价 格:¥电议型 号:TN2296产 地:中国大陆
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T9878CroconazoleCROCONAZOLE
Croconazole exhibited dose-dependent inhibitory activity on the 5-lipoxygenase (5-LOX) of neutrophils. Croconazole is an antimycotic agent. The IC50s for the synthesis of leukotriene B4 (LTB4) and 5-hydroxyeicosatetraenoic acid (5-HETE) is 7.8 +/- 1.7 and
价 格:¥电议型 号:T9878产 地:中国大陆
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TN2108ProtohypericinProtohypericin,naphthodianthrone,Inhibitor,NSCLC,inhibit
Protohypericin is a naturally occurring naphthodianthrone derived from plant Hypericum perforatum.Radioiodinated protohypericin is used in Tumor necrosis targeted radiotherapy. Protohypericin exhibits photocytotoxicity.
价 格:¥电议型 号:TN2108产 地:中国大陆
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T6S1369Vitexinneurodegeneration,Vitexin,anti-cancer,anti-nociceptive,inhibit,Medicinal,anti-hypertensive,an
1. Vitexin has antinociceptive and antispasmodic activities. 2. Vitexin exhibits a prominent first-pass effect. 3. Vitexin has antioxidant, antimyeloperoxidase, and α-glucosidase inhibitory activities. 4. Vitexin can either inhibit or induce activities of CYP2C11 and CYP3A1. 5. Vitexin induces the novel p53-dependent metastatic and apoptotic pathway. 6. Vitexin protects brain against cerebral I/R injury, and this effect may be regulated by mitogen-activated protein kinase (MAPK) and apoptosis si
价 格:¥电议型 号:T6S1369产 地:中国大陆
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T8461SKI VPI3K,SKI V,Inhibitor,Apoptosis,GST-hSK,sphingosine,second,mitogenic,Phosphoinositide 3-kinase,S
SKI V is a potent and noncompetitive non-lipid sphingosine kinase (SPHK; SK) inhibitor (GST-hSK,IC50 : 2 μM), and is a PI3K inhibitor(hPI3k,IC50 : 6 μM), induces apoptosis and has antitumor activity
价 格:¥电议型 号:T8461产 地:中国大陆
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T7833TLX agonist 1TLX agonist-1,transcriptional,TLX agonist 1,repressive,Inhibitor,ligand,inhibit,TLX ago
TLX agonist 1 is an orphan nuclear receptor tailless (TLX, NR2E1) modulator
价 格:¥电议型 号:T7833产 地:中国大陆
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TN1576Diallyl disulfidecholesterol biosynthesis,squalene monooxygenase,Inhibitor,inhibit,Diallyl disulfide
Diallyl disulfide has antitumor effect, the effect can be enhanced by miR-200b and miR-22.
价 格:¥电议型 号:TN1576产 地:中国大陆
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T21861Drinabant
Drinabant is an orally active CB1 receptor antagonist. Drinabant inhibits the agonist-stimulated calcium signal with IC50 values of 25 nM and 10 nM for the hCB1-R and rCB1-R, respectively, and is ineffective for the hCB2-R.
价 格:¥电议型 号:T21861产 地:中国大陆
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T8606n-acetylciprofloxacinnacetylciprofloxacin,n acetylciprofloxacin
n-acetylciprofloxacin is inhibitor of H37Rv.
价 格:¥电议型 号:T8606产 地:中国大陆
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T1782LCanagliflozin hemihydrate
Canagliflozin hemihydrate is a drug of the gliflozin class or subtype 2 sodium-glucose transport inhibitors used for the treatment of type 2 diabetes. SGLT2 is responsible for at least 90% of renal glucose reabsorption (SGLT1 being responsible for the remaining 10%). Blocking this transporter causes up to 119 grams of blood glucose per day to be eliminated through the urine, corresponding to 476 kilocalories.
价 格:¥电议型 号:T1782L产 地:中国大陆
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T7297KG-501Epigenetic Reader Domain,inhibit,Inhibitor,KG 501,Naphthol AS-E,KG501,KG-501
KG-501 is a cAMP response element-binding protein (CREB) inhibitor(IC50 : 6.89 μM).
价 格:¥电议型 号:T7297产 地:中国大陆
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T7846Aegelineαsyn,Aegeline,yeast,Inhibitor,protein,Sec22p,inhibit,toxicity,Fungal,SNARE
Aegeline is an alkaloidal-amide, isolated from the leaves of Aegle marmelos and have shown antihyperglycemic as well as antidyslipidemic activities in the validated animal models of type 2 diabetes mellitus.
价 格:¥电议型 号:T7846产 地:中国大陆
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T6940PHA-767491 hydrochloridePHA767491,PHA 767491,inhibit,CAY-10572,Cyclin dependent kinase,CDK,CAY 10572
PHA-767491 is an effective ATP-competitive dual Cdc7/CDK9 inhibitor (IC50: 10/34 nM). It has ~20-fold selectivity against GSK3-β and CDK1/2, 50-fold selectivity against CDK5 and MK2, 100-fold selectivity against CHK2 and PLK1.
价 格:¥电议型 号:T6940产 地:中国大陆
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T8419XP-59XP 59,XP59,inhibit,Inhibitor,SARS-CoV,XP-59,SARS coronavirus
XP-59 is a potent the SARS-CoV Mpro inhibitor(Ki : 0.1 μM).
价 格:¥电议型 号:T8419产 地:中国大陆
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T6S1572Sauchinoneantioxidant,LPS,Diastereomeric,TNF-α,iNOS,anti-inflammatory,lignan,COX-2,inhibit,Nuclear f
1. Sauchinone is a useful adjunctive treatment for bacterial infection. 2. Sauchinone, an active lignan found in Saururus chinensis, to regulate the activation of HSCs, to prevent liver fibrosis, and to inhibit oxidative stress in vivo and in vitro. 3. Sauchinone diminishes LPS-induced neutrophil activation and acute lung injury. 4. Sauchinone-induced HO-1 expression plays a key role in the vascular protective effects of Sauchinone in HUVEC. 5. Sauchinone protects skin keratinocytes through inhi
价 格:¥电议型 号:T6S1572产 地:中国大陆
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T6566Levobupivacaine hydrochlorideCNS toxicity,gastric cancer,Na channels,Erastin,Inhibitor,analgesic,ana
Levobupivacaine HCl is a reversible neuronal sodium channel inhibitor, which is the pure S(-)-enantiomer of bupivacaine. It was utilized as a long-acting local anesthetic.
价 格:¥电议型 号:T6566产 地:中国大陆
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T8678NaphthazarinNaturally,Apoptosis,Naphthazarin,stress,microtubules,mitochondrial,AIF,Inhibitor,p21,lys
Naphthazarin is effective by various cellular mechanisms including oxidative stress, activation of mitochondrial apoptosis-inducing factor (AIF), depolymerization of microtubules, interference with lysosomal function and p53-dependent p21 activation. It triggers apoptosis and has anti-tumor effects
价 格:¥电议型 号:T8678产 地:中国大陆