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T16510PF-915275
PF-915275 is an effective and selective inhibitor of human 11β-hydroxysteroid dehydrogenase type 1 (11βHSD1, Ki = 2.3 nM, EC50 = 15 nM in vitro HEK293 cells). The dose-dependent effect of PF-915275 on conversion of cortisone to cortisol in primary human a
价 格：￥电议型 号：T16510产 地：中国大陆
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T16508PF-5190457PF-05190457
PF-5190457 is an effective and selective ghrelin receptor inverse agonist (pKi: 8.36).
价 格：￥电议型 号：T16508产 地：中国大陆
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T16506PF-48786913M-852A
PF-4878691 is an effective and selective Toll-like receptor 7 agonists modelled. It is used to dissociate its antiviral and inflammatory activities.
价 格：￥电议型 号：T16506产 地：中国大陆
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T16503PF-4191834PF-04191834
PF-4191834 is a noniron chelating and non-redox inhibitor of the 5-Lipoxygenase (5-LOX) with an IC50 of 229 nM. PF-4191834 shows ~300-fold selectivity for 5-LOX over 12-LOX and 15-LOX and displays no activity toward the cyclooxygenase enzymes. PF-4191834
价 格：￥电议型 号：T16503产 地：中国大陆
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T16501PF-3644022
PF-3644022 is an effective, selective, and ATP-competitive MAPKAPK2 (MK2) inhibitor (IC50: 5.2 nM and a Ki of 3 nM). PF-3644022 potently inhibits TNFα production and has an anti-inflammatory effect. PF-3644022 also inhibits MK3 and p38 regulated/activated
价 格：￥电议型 号：T16501产 地：中国大陆
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T16500PF-3450074PF-74
PF-3450074 acts at an early stage of HIV-1 infection inhibits viral replication by directly competing with the binding of CPSF6 (nuclear host factors cleavage and polyadenylation specific factor 6) and NUP153 (nucleoporin 153), and blocks the uncoating, a
价 格：￥电议型 号：T16500产 地：中国大陆
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T16499MardepodectPF-2545920
Mardepodect is a phosphodiesterase inhibitor selective for the PDE10A subtype with an IC50 of 0.37 nM, >1000-fold selectivity over PDE. It is potentially useful for the treatment of schizophrenia. Phosphodiesterase 10A (PDE10A) is highly expressed in stri
价 格：￥电议型 号：T16499产 地：中国大陆
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T16492PF-06459988
PF-06459988 is an irreversible T790M-Containing EGFR Mutants inhibitor.
价 格：￥电议型 号：T16492产 地：中国大陆
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T16486Mal-amido-PEG2-C2-amido-Ph-C2-CO-AZDPF-05231023
PF-05231023 is a long-acting fibroblast growth factor 21 (FGF21) analog and is an FGF21-receptor agonist. It is also suitable for development as a potential treatment for T2DM.
价 格：￥电议型 号：T16486产 地：中国大陆
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T16483PF-05105679
PF-05105679 is a selective TRPM8 antagonist (IC50 = 103 nM). PF-05105679 can be used in research on cold-related pain.
价 格：￥电议型 号：T16483产 地：中国大陆
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T16481PF-04995274
PF-04995274 is an effective, high-affinity, and partial serotonin 4 receptor (5-HT4R) agonist. PF-04995274 is brain penetrant and can be used for cognitive disorders associated with Alzheimer´s disease. PF-04995274 has an EC50 range of 0.26-0.47 nM for hu
价 格：￥电议型 号：T16481产 地：中国大陆
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T16479PF-04937319
PF-04937319 is an activator of glucokinase (EC50 =154.4 ?μM). PF-04937319 maintains glucose-lowering efficacy while mitigating the risk of hypoglycemia observed with many other glucokinase activators. PF-04937319 can be used in research on the treatment o
价 格：￥电议型 号：T16479产 地：中国大陆
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T16476PF-03654746
PF-03654746 decreases allergen-induced nasal symptoms might be a novel therapeutic strategy to further explore allergic rhinitis. PF-03654746 is an effective and selective antagonist of the histamine H3 receptor. It has high brain penetration. PF-03654746
价 格：￥电议型 号：T16476产 地：中国大陆
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T16471PerflubronPFOB；Perfluorooctyl bromide；全氟溴辛烷
Perflubron can be emulsified with egg phospholipids (EYP) and displays exceptionally fast excretion characteristics. Perflubron(1-Bromoheptadecafluorooctane; Heptadecafluorooctyl bromide; Perfluorooctyl bromide) is a contrast medium for magnetic resonance
价 格：￥电议型 号：T16471产 地：中国大陆
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T15244Ertugliflozin L-pyroglutamic acidPF-04971729 L-pyroglutamic acid
Ertugliflozin L-pyroglutamic acid is a selective and orally active hSGLT2 inhibitor with an IC50 of 0.877 nM. Ertugliflozin L-pyroglutamic acid can be used for studies about the treatment of type 2 diabetes mellitus.
价 格：￥电议型 号：T15244产 地：中国大陆
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T14920CE-224535PF-04905428
CE-224535 is a selective antagonist of P2X7 receptor. CE-224535 can be used in disease-modifying antirheumatic studies.
价 格：￥电议型 号：T14920产 地：中国大陆
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T14365AZ PFKFB3 26
AZ PFKFB3 26 is an effective and selective PFKFB3 inhibitor with an IC50 of 23 nM. The IC50s for PFKFB1 and PFKFB2 are 2.06 and 0.384 μM, respectively.
价 格：￥电议型 号：T14365产 地：中国大陆
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T12472Pifithrin-α, p-Nitro, CyclicPFN-α
Pifithrin-α, p-Nitro, Cyclic (PFN-α) is cell-permeable and active-form inhibitor of p53.
价 格：￥电议型 号：T12472产 地：中国大陆
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T12438PfDHODH-IN-1
PfDHODH-IN-1 is an inhibitor of Plasmodium falciparum dihydroorotate dehydrogenase(PfDHODH) which catalyzes the rate-limiting step for DNA and RNA biosynthesis. PfDHODH-IN-1 has antimalarial activity.
价 格：￥电议型 号：T12438产 地：中国大陆
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T12437PF429242 dihydrochloride
PF429242 dihydrochloride can reversibly inhibit S1P (IC50 of 175 nM).
价 格：￥电议型 号：T12437产 地：中国大陆
