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T9287HydroxychloroquineParasite,Toll-like Receptor (TLR),SARS-CoV,Inhibitor,SARS coronavirus,Autophagy,Hy
Hydroxychloroquine (HCQ) is an alkalinizing lysosomatropic drug that acts by inducing apoptosis of renal cancer cells in vitro and inhibiting TLR7/9. It is a medication used to prevent and treat malaria, and it´s also being studied as an experimental treatment for COVID-19.
价 格:¥电议型 号:T9287产 地:中国大陆
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T7114GALANTHAMINONEGALANTHAMINONE,inhibit,Inhibitor,Cholinesterase (ChE)
Galanthaminone is a cholinesterase (AChE) inhibitor, is used for the treatment of mild to moderate Alzheimer´s disease and various other memory impairments.
价 格:¥电议型 号:T7114产 地:中国大陆
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T7307Vorasidenibinhibit,AG 881,Vorasidenib,AG881,Inhibitor,Isocitrate Dehydrogenase (IDH)
Vorasidenib is an inhibitor of mutant isocitrate dehydrogenase (IDH; IC50s = 31.9 and 31.7 nM for IDH1R132H and IDH2R140Q, respectively)
价 格:¥电议型 号:T7307产 地:中国大陆
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T0096VardenafilPhosphodiesterase (PDE),erectile dysfunction,stimulation,diabetes,Zucker diabetic fatty (Z
Vardenafil (Levitra) is an oral therapy for the treatment of erectile dysfunction. It is a selective inhibitor of cyclic guanosine monophosphate (cGMP)-specific phosphodiesterase type 5 (PDE5). Penile erection is a hemodynamic process initiated by the relaxation of smooth muscle in the corpus cavernosum and its associated arterioles. During sexual stimulation, nitric oxide is released from nerve endings and endothelial cells in the corpus cavernosum. Nitric oxide activates the enzyme guanylate c
价 格:¥电议型 号:T0096产 地:中国大陆
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T6941PI-1840cell proliferation,Proteasome,Caspase,proteasome substrates,poly ADP ribose polymerase,inhibi
PI-1840( IC50 = 27 nM)is a reversible and selective chymotrypsin-like (CT-L) inhibitor, with little proteasome proteolytic effects on trypsin-like (T-L) and postglutamyl-peptide-hydrolysis-like (PGPH-L).
价 格:¥电议型 号:T6941产 地:中国大陆
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T6623OxibendazoleInhibitor,Apoptosis,inhibit,Parasite,Oxibendazole
Oxibendazole is a benzimidazole drug that interferes with metabolic pathways, used to protect against roundworms, strongyles, threadworms, pinworms and lungworm infestations in horses and some domestic pets.
价 格:¥电议型 号:T6623产 地:中国大陆
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T6420BMS-707035BMS 707035,HIV-1 integrase strand transfer,HIV,Human immunodeficiency virus,antiviral,BMS7
BMS-707035 is a specific HIV-I integrase (IN) inhibitor with IC50 of 15 nM. Phase 2.
价 格:¥电议型 号:T6420产 地:中国大陆
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TN1078SeneciphyllineP-450,hydrase,Inhibitor,Gutathione S-transferase,Cytochrome P450,Toxic,alkaloid,cytoch
Seneciphylline, one of the hepatotoxic pyrolizidine alkaloids, has mutagenic activity in Drosophila and their transfer into rat milk.Seneciphylline can significantly increased the activities of epoxide hydrase and glutathione-S-transferase but cause reduction of cytochrome P-450 and related monooxygenase activities.
价 格:¥电议型 号:TN1078产 地:中国大陆
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TN1858LeptomerineCholinesterase (ChE),acetyl,inhibit,Inhibitor,cholinesterase,Anticholinesterasic,Leptomer
Leptomerine is an alkaloid from stems of Esenbeckia leiocarpa Engl. (Rutaceae). Leptomerine shows as anticholinesterasic activity and can be used in Alzheimer Disease studies.
价 格:¥电议型 号:TN1858产 地:中国大陆
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T6649(S)-(+)-RolipramTNFα,tumor,inhibit,(S)(+)Rolipram,mononuclear,Apoptosis,phosphodiesterase,(S) (+) Ro
S-(+)-Rolipram inhibits human monocyte cyclic AMP-specific PDE4 with IC50 of 0.75 μM, has anti-inflammatory and anti-depressant activity in the central nervous system, less potent than its R enantiomer.
价 格:¥电议型 号:T6649产 地:中国大陆
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T8827EMAC10101dEMAC-10101d,Carbonic Anhydrase,hCA II,EMAC10101d,Inhibitor,inhibit,Carbonate dehydratase
compound EMAC10101d, bearing a 2,4-dichorophenyl substituent in position 4 of the dihydrothiazole ring, was the most potent and selective toward hCA II with an inhibitory activity in the low nanomolar range.
价 格:¥电议型 号:T8827产 地:中国大陆
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T6483EHT 1864EHT 1864,precursor,β-amyloid,protein,disease,Alzheimer,amyloid,EHT-1864,EHT1864,Ras,inhibit,
EHT 1864 is a effective Rac family GTPase inhibitor for Rac1/Rac1b/Rac2/Rac3 (Kd: 40/50/60/250 nM).
价 格:¥电议型 号:T6483产 地:中国大陆
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T8150NudifloramidePARP,nicotinamide-adenine,poly ADP ribose polymerase,PARP-1,failure,chronic,Nudiflorami
1-Methyl-6-oxo-1,6-dihydropyridine-3-carboxamide is one of the end degradation products of nicotinamide-adenine dinucleotide (NAD).
价 格:¥电议型 号:T8150产 地:中国大陆
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T7089SGC2085SGC2085,SGC 2085,Inhibitor,inhibit,SGC-2085,Histone Methyltransferase
SGC2085 is an effective and selective coactivator-associated arginine methyltransferase 1 (CARM1) inhibitor (IC50: 50 nM).
价 格:¥电议型 号:T7089产 地:中国大陆
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T6407β-LapachoneARQ 501,ARQ501,Topoisomerase,Inhibitor,NSC26326,β-Lapachone,Apoptosis,NSC 26326,Autophagy
Beta-Lapachone is a specific DNA topoisomerase I inhibitor, and no inhibitory activities against DNA topoisomerase II or ligase.
价 格:¥电议型 号:T6407产 地:中国大陆
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T6S2391L-Chicoric Acidreplication,Inhibitor,L-Chicoric Acid,HIV Integrase,L Chicoric Acid,dicaffeoyltartari
L-Chicoric acid has been shown to inhibit hyaluronidase and HIV-1 integrase, and to possess phagoeytosis stimulatory activity in vitro and in vivo and antiviral acitivy. L-Chicoric acid may reduce acute alcohol-induced steatosis in mice through interfering with the induction of iNOS and iNOS-dependent signaling cascades in the liver. 3. L-Chicoric acid inhibited cell viability and induced apoptosis in 3T3-L1 preadipocytes which was characterized by chromatin condensation and poly ADP-ribose-poly
价 格:¥电议型 号:T6S2391产 地:中国大陆
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T9165AZD5305repair,AZD5305,Inhibitor,poly ADP ribose polymerase,DNA,AZD-5305,PARP,inhibit,pathway,synthet
AZD5305 is a potent, selective and oral active PARP inhibitor.
价 格:¥电议型 号:T9165产 地:中国大陆
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T13619Cloperastine fendizoate
Cloperastine fendizoate inhibits the hERG K+ currents in a concentration-dependent manner (IC50: 27 nM).
价 格:¥电议型 号:T13619产 地:中国大陆
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TN7028Picras-3-en-16-one, 11,20-epoxy-2-(β-D-glucopyranosyloxy)-1,11,12,14,15-pentahydroxy-, (1β,2α,11β,12
Picras-3-en-16-one, 11,20-epoxy-2-(β-D-glucopyranosyloxy)-1,11,12,14,15-pentahydroxy-, (1β,2α,11β,12α,15β)- is a chemical compound.
价 格:¥电议型 号:TN7028产 地:中国大陆
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T62228KRAS G12D inhibitor 14
KRAS G12D inhibitor 14 is an effective inhibitor of KRAS G12D, showing significant antitumor effect and tumor growth inhibition in CT26 tumor models.
价 格:¥电议型 号:T62228产 地:中国大陆