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T77890TLR7/8 agonist 4 hydroxy-PEG6-acid hydrochloride;化合物 TLR7/8 agonist 4 hydroxy-PEG6-acid hydrochlorid
TLR7/8 agonist 4 hydroxy-PEG6-acid hydrochloride, a Drug-Linker Conjugate for ADC synthesis, is the hydrochloride variant of TLR7/8 agonist 4 hydroxy-PEG6-acid, comprising the TLR7/8 agonist 4 component attached to the hydroxy-PEG6-acid linker [1].
价 格:¥电议型 号:T77890产 地:中国大陆
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T77343Compound STL565749;化合物 STL565749Compound STL565749
Compound STL565749 is a useful organic compound for research related to life sciences. The catalog number is T77343 and the CAS number is 879771-67-2.
价 格:¥电议型 号:T77343产 地:中国大陆
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T77055Lenercept;化合物 LenerceptLenercept
Lenercept (Ro 45-2081) is a recombinant fusion protein combining the soluble TNF-receptor (p55) with the Fc portion of human IgG1 [1].
价 格:¥电议型 号:T77055产 地:中国大陆
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T7672MD2-TLR4-IN-1;化合物MD2-TLR4-IN-1MD2-TLR4-IN-1
MD2-TLR4-IN-1 is a myeloid differentiation protein 2/toll-like receptor 4 (MD2-TLR4) complex inhibitor.
价 格:¥电议型 号:T7672产 地:中国大陆
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T7649516-38-Thymosin β4 (cattle);化合物 16-38-Thymosin β4 (cattle)16-38-Thymosin β4 (cattle)
Thymosin β4 (cattle), a Ca2+-independent MLCK activator, demonstrates high affinity [1].
价 格:¥电议型 号:T76495产 地:中国大陆
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T76423Neuropeptide AF (cattle);化合物 Neuropeptide AF (cattle)Neuropeptide AF (cattle)
Neuropeptide AF (cattle), an amidated octadecapeptide and RFamide neuropeptide, serves as a ligand for Mas-related gene receptor A4 (MrgprA4) (Mas-related G-protein-coupled Receptor (MRGPR)) with an EC50 of approximately 60 nM, and MrgprC11 with an EC50 of around 300 nM. It also activates G protein-coupled receptors NPFF1 (Neuropeptide Y Receptor) with an EC50 ranging from ~25 to 325 nM, and NPFF2 with an EC50 of approximately 1 to 5 nM. Furthermore, Neuropeptide AF (cattle) exhibits anti-opiate
价 格:¥电议型 号:T76423产 地:中国大陆
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T76368VSPPLTLGQLLS TFA;化合物 VSPPLTLGQLLS TFAVSPPLTLGQLLS TFA
VSPPLTLGQLLS TFA, a small peptide FGFR3 inhibitor also known as peptide P3, effectively inhibits FGFR3 phosphorylation. It also prevents 9-cisRA-induced tracheal lymphangiogenesis and impedes lymphatic endothelial cell (LEC) proliferation, migration, and tubule formation [1] [2].
价 格:¥电议型 号:T76368产 地:中国大陆
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T76367VSPPLTLGQLLS;化合物 VSPPLTLGQLLSVSPPLTLGQLLS
VSPPLTLGQLLS, also known as peptide P3, is a small peptide that serves as an inhibitor of FGFR3, effectively suppressing FGFR3 phosphorylation. It hinders 9-cisRA-induced tracheal lymphangiogenesis and impedes lymphatic endothelial cell (LEC) activities, including proliferation, migration, and tubule formation [1] [2].
价 格:¥电议型 号:T76367产 地:中国大陆
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T76209DSTYSLSSTLTLSK TFA;化合物 DSTYSLSSTLTLSK TFADSTYSLSSTLTLSK TFA
DSTYSLSSTLTLSK TFA, a generic human peptide, facilitates the quantitative detection of Infliximab (Avakine), a chimeric monoclonal IgG1 antibody targeting TNF-α, as indicated in study [1].
价 格:¥电议型 号:T76209产 地:中国大陆
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T76017CTTHWGFTLC, CYCLIC TFA;化合物 CTTHWGFTLC, CYCLIC TFACTTHWGFTLC, CYCLIC TFA
CTTHWGFTLC, also known as CYCLIC TFA, is a cyclic peptide that acts as an inhibitor of matrix metalloproteinases (MMP-2 and MMP-9), with an IC50 value of approximately 8 μM for MMP-9 [1].
价 格:¥电议型 号:T76017产 地:中国大陆
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T75957Sphistin Synthetic Peptide(12-38,Fitc in N-Terminal-Fluorescently Labeled Peptide);化合物 Sphistin Synt
Sphistin Synthetic Peptide (12-38, Fitc in N-Terminal-Fluorescently Labeled Peptide) represents truncated fragments of the parent Sphistin Synthetic Peptide, characterized by the presence of a fluorescent label (Fitc) at the N-terminal.
价 格:¥电议型 号:T75957产 地:中国大陆
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T75213TLR7 agonist 12;化合物 TLR7 agonist 12TLR7 agonist 12
TLR7 agonist 12 (example 20), a purine nucleoside analog, functions as a TLR7 agonist with broad antitumor activity, particularly against indolent lymphoid malignancies. Its anticancer mechanisms include DNA synthesis inhibition, apoptosis induction, among others [1] [2].
价 格:¥电议型 号:T75213产 地:中国大陆
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T75153ATL 1102;化合物 ATL 1102ATL 1102
ATL 1102 is a novel second-generation antisense oligonucleotide to CD49d mRNA
价 格:¥电议型 号:T75153产 地:中国大陆
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T74864TL4830031;化合物 TL4830031TL4830031
TL4830031 (compound 8i), a derivative of quinolone antibiotics, serves as a potent Axl inhibitor, displaying an IC50 value of 26 nM. It effectively inhibits the phosphorylation of Axl, as well as cell invasion and migration, showcasing its potential utility in cancer research [1].
价 格:¥电议型 号:T74864产 地:中国大陆
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T74468MC-Val-Cit-PAB-Amide-TLR7 agonist 4;化合物 MC-Val-Cit-PAB-Amide-TLR7 agonist 4MC-Val-Cit-PAB-Amide-TLR7
MC-Val-Cit-PAB-Amide-TLR7 agonist 4 (example 15) is a conjugate that acts as an immune agonist targeting both HER2-TLR7 and HER2-TLR8 pathways [1].
价 格:¥电议型 号:T74468产 地:中国大陆
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T74389Tri(TLR4-IN-C34-C2-amide-C3-amide-PEG1)-amide-C3-COOH;化合物 Tri(TLR4-IN-C34-C2-amide-C3-amide-PEG1)-am
Tri(TLR4-IN-C34-C2-amide-C3-amide-PEG1)-amide-C3-COOH, a chemical compound, serves as a linker incorporating TLR4 inhibitor TLR4-IN-C34. This compound effectively inhibits TLR4 in both enterocytes and macrophages, significantly reducing systemic inflammation in mouse models of endotoxemia and necrotizing enterocolitis [1].
价 格:¥电议型 号:T74389产 地:中国大陆
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T74388Tri(TLR4-IN-C34-PEG2-amide-PEG1)-amide-C3-COOH;化合物 Tri(TLR4-IN-C34-PEG2-amide-PEG1)-amide-C3-COOHTri
Tri(TLR4-IN-C34-PEG2-amide-PEG1)-amide-C3-COOH is a chemical linker incorporating the TLR4 inhibitor, TLR4-IN-C34, which suppresses TLR4 activity in enterocytes and macrophages, consequently diminishing systemic inflammation observed in mouse models of endotoxemia and necrotizing enterocolitis [1].
价 格:¥电议型 号:T74388产 地:中国大陆
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T74387Tri(TLR4-IN-C34-C2-amide-PEG1)-amide-C3-COOH;化合物 Tri(TLR4-IN-C34-C2-amide-PEG1)-amide-C3-COOHTri(TLR
Tri(TLR4-IN-C34-C2-amide-PEG1)-amide-C3-COOH is a chemical linker featuring the TLR4 inhibitor TLR4-IN-C34, known for inhibition of TLR4 in enterocytes and macrophages, thereby diminishing systemic inflammation in mouse models of endotoxemia and necrotizing enterocolitis [1].
价 格:¥电议型 号:T74387产 地:中国大陆
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T74383TLR4-IN-C34-C2-amide-C6-OH;化合物 TLR4-IN-C34-C2-amide-C6-OHTLR4-IN-C34-C2-amide-C6-OH
TLR4-IN-C34-C2-amide-C6-OH, a chemical compound, serves as a linker encompassing the TLR4 inhibitor TLR4-IN-C34. This inhibitor is known to target TLR4 in enterocytes and macrophages, effectively reducing systemic inflammation in mouse models of endotoxemia and necrotizing enterocolitis [1].
价 格:¥电议型 号:T74383产 地:中国大陆
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T74018cGMP-HTL;化合物 cGMP-HTLcGMP-HTL
cGMP-HTL, an autophagy-targeting chimera (AUTAC), consists of a HT-ligand, a linker, and a Cys-S-cGMP (autophagy tag), designed to enhance K63-linked ubiquitination of mitochondria. This novel clearance strategy features a degradation tag (guanine derivatives) and a specific warhead, facilitating targeted degradation [1].
价 格:¥电议型 号:T74018产 地:中国大陆