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T11588Hydroxybupropion
Hydroxybupropion is the major active metabolite of Bupropion and an antagonist of nACh receptor. Hydroxybupropion inhibits norepinephrine uptake (IC50 = 1.7 μM).
价 格:¥电议型 号:T11588产 地:中国大陆
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T9014SKI-178resistant,SphK,cytotoxic,myeloid,Inhibitor,Apoptosis,leukemia,multi-drug,inhibit,SKI-178,canc
SKI-178 is a sphingosine kinase 1 (SphK1) inhibitor with IC50 of 0.1-1.8 μM. It induces prolonged mitosis followed by apoptotic cell death through the intrinsic apoptotic cascade. The sustained activation of CDK1 during prolonged mitosis, mediated by SKI-178 leads to the simultaneous phosphorylation of the prosurvival Bcl-2 family members, Bcl-2 and Bcl-xl, as well as the phosphorylation and subsequent degradation of Mcl-1.
价 格:¥电议型 号:T9014产 地:中国大陆
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T7882Indomethacin farnesilAutophagy,inhibit,flux,Inhibitor,Indomethacin farnesil,cox1,COX,pain,Cyclooxyge
Infree is a prodrug of indomethacin. It acts as a nonsteroidal anti-inflammatory drug (NSAID) and disease-modifying anti-rheumatic drug (DMARD).
价 格:¥电议型 号:T7882产 地:中国大陆
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TQ0097AGN 193109AGN193109,Autophagy,Inhibitor,Retinoic acid receptors,Retinoid X receptors,RAR/RXR,AGN 193
AGN 193109, a retinoid analog, is a potent and specific antagonist of RARs (Kds: 2 nM, 2 nM, and 3 nM for RARα, RARβ, and RARγ).
价 格:¥电议型 号:TQ0097产 地:中国大陆
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T8842IMT1BInhibitor,inhibit,POLRMT,oxidative,IMT-1B,LDC-203974,human,LDC 203974,anti-tumour,mtDNA,phospho
IMT1B is an orally active, noncompetitive and specific allosteric inhibitor of mitochondrial RNA polymerase (POLRMT) and inhibits mitochondrial DNA (mtDNA) expression. It has anti-tumour effects.
价 格:¥电议型 号:T8842产 地:中国大陆
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T7304DNQXinhibit,nucleus,selective,thalamic,Ionotropic glutamate receptors,Inhibitor,quinoxaline,DNQX,FG-
DNQX is a competitive, non-NMDA glutamate receptor antagonist (IC50s = 0.5 and 0.1 μM for AMPA and kainate receptors, respectively)
价 格:¥电议型 号:T7304产 地:中国大陆
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T357042-Methoxybenzaldehyde
2-Methoxybenzaldehyde (o-Anisaldehyde), isolated from cinnamon essential oil (CEO), exists antibacterial and antifungal activity[1].
价 格:¥电议型 号:T35704产 地:中国大陆
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T60205(2S)-4-biphenyl-4-yl-N-hydroxy-2-methyl-2-(methylsulfonyl)butanamide(2S)4biphenyl4ylNhydroxy2methyl2
(2S)-4-biphenyl-4-yl-N-hydroxy-2-methyl-2-(methylsulfonyl)butanamide is a LpxC inhibitor with IC50 >95.2 nM.
价 格:¥电议型 号:T60205产 地:中国大陆
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T79912-Hydroxycinnamic acidSARS coronavirus,Human immunodeficiency virus,inhibit,2Hydroxycinnamic acid,In
2-Hydroxycinnamic acid is a natural product isolated from Angraecum fragrans, has photooxidant activity.
价 格:¥电议型 号:T7991产 地:中国大陆
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T7336ICA-121431Nav,Na channels,inhibitor,ICA-121431,ICA 121431,TTX-resistant,Sodium Channel,channel,Na+ c
ICA-121431 is a nanomolar potent small molecule Nav1.7 channel inhibitor with IC50 of 19 nM for rat Nav1.7, with little or no activity against human Nav1.5 or Nav1.7 channels.
价 格:¥电议型 号:T7336产 地:中国大陆
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TN2330Phenethyl ferulatePhenethyl ferulate,Lipoxygenase,5-LOX,Cyclooxygenase,Inhibitor,5-lipoxygenase,inhi
Caffeic Acid 3-Methyl Phenethyl Ester has chemopreventive properties against chemically induced colon carcinogenesis. It enhances apoptosis in azoxymethane induced colon tumors. It shows inhibitory activity against cyclooxygenase (COX) and 5-lipoxygenase (5-LOX) with IC50 values of 4.35 μM and 5.75 μM, respectively.
价 格:¥电议型 号:TN2330产 地:中国大陆
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TN7074(2E)-3-(1,3-Benzodioxol-5-yl)-2-propenoic acidBrombya platynema,(2E) 3 (1,3 Benzodioxol 5 yl) 2 prop
(2E)-3-(1,3-Benzodioxol-5-yl)-2-propenoic acid displays EC50 values of 73.5 μM against T. cruzi. trypomastigotes.
价 格:¥电议型 号:TN7074产 地:中国大陆
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T6466Dexmedetomidine hydrochlorideinhibit,Inhibitor,adrenoceptor,(+)-Medetomidine,Dexmedetomidine hydroch
Dexmedetomidine hydrochloride is an imidazole derivative that is an agonist of the adrenergic alpha-2 receptor. It is closely-related to MEDETOMIDINE, which is the racemic form of this compound.
价 格:¥电议型 号:T6466产 地:中国大陆
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T6387AmpiroxicamAmpiroxicam,COX,inhibit,CP65703,Cyclooxygenase,CP-65703,Inhibitor
Ampiroxicam is a nonselective cyclooxygenase inhibitor uesd as anti-inflammatory drug.
价 格:¥电议型 号:T6387产 地:中国大陆
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TQ0155Miglustat hydrochlorideN-Butyldeoxynojirimycin,OGT-918,type I gaucher disease,Miglustat,Miglustat hy
Miglustat hydrochloride is an inhibitor of glucosylceramide synthase and can be used for studies about Type I Gaucher disease.
价 格:¥电议型 号:TQ0155产 地:中国大陆
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TP1970LProsaptide TX14(A) acetateProsaptide TX14(A) acetate,Prosaptide TX-14(A) acetate
Prosaptide TX14(A) acetate is a potent GPR37L1 and GPR37 agonist. Prosaptide Tx14(A) TFA increases both ERK1 and ERK2 phosphorylation in Schwann cells.
价 格:¥电议型 号:TP1970L产 地:中国大陆
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T93241,5-diphenylpyrazole-3-carboxylic acid1,5 diphenylpyrazole 3 carboxylic acid,1,5diphenylpyrazole3car
1,5-diphenylpyrazole-3-carboxylic acid is a plant-physiologically tolerable salt radical or any desired ester radical.
价 格:¥电议型 号:T9324产 地:中国大陆
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T8623TMIFRY8XAGTMIFRY8XAG,TMIFRY-8XAG
TMIFRY8XAG is a derivative of Zerumbone with potential anti-tumor effects towards HeLa cancer cells.
价 格:¥电议型 号:T8623产 地:中国大陆
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TN71462,6-Dibromo-4-(hydroxymethyl)phenol
2,6-Dibromo-4-(hydroxymethyl)phenol is a marine derived natural products found in Thelepus setosus.
价 格:¥电议型 号:TN7146产 地:中国大陆
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T643224-(9H-fluoren-9-ylmethoxycarbonylamino)-piperidine-1,4-dicarboxylic acid mono-tert-butyl ester
4-(9H-fluoren-9-ylmethoxycarbonylamino)-piperidine-1,4-dicarboxylic acid mono-tert-butyl ester is a bioactive substances.
价 格:¥电议型 号:T64322产 地:中国大陆