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  • T81859Markogenin；化合物 MarkogeninMarkogenin

    Markogenin, a steroid constituent derived from Yucca schidigera plants [1], exhibits unique properties.

    价 格：￥电议型 号：T81859产 地：中国大陆

  • T81855Marsglobiferin；化合物 MarsglobiferinMarsglobiferin

    Marsglobiferin is a triterpenoid compound that can be isolated from the ethanol extract of calla lily stems.

    价 格：￥电议型 号：T81855产 地：中国大陆

  • T81832MC-VC-PABC-C6-alpha-Amanitin；化合物 MC-VC-PABC-C6-alpha-AmanitinMC-VC-PABC-C6-alpha-Amanitin

    MC-VC-PABC-C6-alpha-Amanitin is an antibody-drug conjugate that combines the anticancer toxin alpha-Amanitin with the monoclonal antibody MC-VC-PABC-C6. Alpha-Amanitin acts as a potent inhibitor of RNA polymerase IIα, enabling the conjugate to selectively target and recognize HER2-positive tumor cells. This specificity makes MC-VC-PABC-C6-alpha-Amanitin a valuable research tool in the study of breast and gastric cancers [1].

    价 格：￥电议型 号：T81832产 地：中国大陆

  • T81808Methylxanthoxylin；化合物 MethylxanthoxylinMethylxanthoxylin

    Methylxanthoxylin, a ketone, can be isolated from the leaves and bark of Acradenia Jianklinii [1].

    价 格：￥电议型 号：T81808产 地：中国大陆

  • T81678NF(N-Me)GA(N-Me)IL；化合物 NF(N-Me)GA(N-Me)ILAmylin (22-27) [NMeG24, NMeI26], human (IAPP)；Amylin (22-27

    NF(N-Me)GA(N-Me)IL is a biologically active peptide, representing a modified segment (amino acids 22 to 27) of the human islet amyloid polypeptide (hIAPP) sequence NFGAIL. This modification includes N-methylations at G24 and I26, transforming the amyloidogenic and cytotoxic nature of the original sequence into a non-amyloidogenic and non-cytotoxic variant. Moreover, the peptide maintains the ability to bind with high affinity to full-length hIAPP, effectively inhibiting its fibril formation.

    价 格：￥电议型 号：T81678产 地：中国大陆

  • T81664NMB-1；化合物 NMB-1NMB-1

    NMB-1, a conopeptide analogue, selectively inhibits sustained mechanically activated currents in sensory neurons with an IC50 of 1 μM, attenuating mechanical pain. It is utilized in research pertaining to hearing and pressure-evoked pain [1] [2].

    价 格：￥电议型 号：T81664产 地：中国大陆

  • T81661NNMT-IN-4；化合物 NNMT-IN-4NNMT-IN-4

    NNMT-IN-4 (compound 38) is a selective, uncompetitive inhibitor of nicotinamide N-methyltransferase (NNMT) with in vitro biochemical and cell-based assay IC50 values of 42 nM and 38 nM, respectively. It demonstrates favorable pharmacokinetics/pharmacodynamics (PK/PD) and safety profiles, excellent oral bioavailability, and promising pharmaceutical properties. NNMT-IN-4 serves as an in vivo chemical probe for NNMT [1].

    价 格：￥电议型 号：T81661产 地：中国大陆

  • T81432PNMT-IN-1；化合物 PNMT-IN-1PNMT-IN-1

    PNMT-IN-1 (inhibitor 4) is a selective second generation inhibitor [1] of phenylethanolamine N-methyltransferase (PNMT), exhibiting a Ki value of 1.2 nM and an IC50 value of 81 nM. Additionally, it disrupts the activity of DNMT1 and DNMT3b, with IC50 values of 61 μM and 17 μM, respectively, and antagonizes the action of epinephrine.

    价 格：￥电议型 号：T81432产 地：中国大陆

  • T81140SNM1A-IN-1；化合物 SNM1A-IN-1SNM1A-IN-1

    SNM1A-IN-1 (compound 11a) serves as an inhibitor of the DNA damage repair enzyme SNM1A, exhibiting cytotoxic properties [1].

    价 格：￥电议型 号：T81140产 地：中国大陆

  • T80594Ormutivimab；化合物 OrmutivimabrhRIG|||NM57；rhRIG|||NM57

    Ormutivimab (rhRIG), a recombinant human monoclonal antibody designed to target the rabies virus, effectively neutralizes various strains and demonstrates strong efficacy as a post-exposure prophylaxis (PEP) treatment in model studies [1] [2].

    价 格：￥电议型 号：T80594产 地：中国大陆

  • T80554Myoregulin；化合物 MyoregulinMLN peptide；MLN peptide

    Myoregulin (MLN peptide), a regulin family member, modulates muscle performance through intracellular calcium handling. It directly interacts with the sarcoplasmic reticulum Ca^2+-ATPase (SERCA), impeding Ca^2+ uptake into the sarcoplasmic reticulum [1] [2].

    价 格：￥电议型 号：T80554产 地：中国大陆

  • T80489MmTx1 toxin；化合物 MmTx1 toxinMicrurotoxin 1；Micrurotoxin 1

    Micrurotoxin 1 (MmTx1 toxin) acts as an allosteric modulator of GABA A receptors, enhancing the receptor´s sensitivity to its agonist [1].

    价 格：￥电议型 号：T80489产 地：中国大陆

  • T80487MmTx2 toxin；化合物 MmTx2 toxinMicrurotoxin 2；Micrurotoxin 2

    MmTx2 toxin, extracted from the venom of the coral snake, serves as a modulator of the GABA A receptor, increasing its responsiveness to agonists. This property renders it a useful tool in researching neurological disorders, including epilepsy, schizophrenia, and chronic pain [1].

    价 格：￥电议型 号：T80487产 地：中国大陆

  • T80180Maurotoxin；化合物 MaurotoxinMaurotoxin

    Maurotoxin, a 34-residue peptide featuring four disulfide bridges, is extracted from the chactoid scorpion (Scorpio maurus) and known to impede Shaker potassium channels (ShB) K+ flow, exhibiting an IC50 of 2 nM [1] [2].

    价 格：￥电议型 号：T80180产 地：中国大陆

  • T80080PAMP-12 (unmodified) (TFA)；化合物 PAMP-12 (unmodified) (TFA)PAMP-12 (unmodified) (TFA)

    PAMP-12 (unmodified) TFA, an endogenous peptide and potent MRGPRX2 (MrgX2) agonist (EC50=20-50 nM), induces hypotension by inhibiting catecholamine secretion from sympathetic nerve endings and adrenal chromaffin cells [1].

    价 格：￥电议型 号：T80080产 地：中国大陆

  • T79940Moracin N；化合物 Moracin NMoracin N

    Moracin N, a ferroptosis inhibitor derived from mulberry leaves, exhibits neuroprotective activity by mitigating oxidative stress [1].

    价 格：￥电议型 号：T79940产 地：中国大陆

  • T79931Mutanocyclin；化合物 MutanocyclinMutanocyclin

    Mutanocyclin, a powerful antifungal agent, inhibits the filamentation of Candida albicans (C. albicans) and decreases the mRNA expression of HWP1, ECE1, FLO8, TEC1. Furthermore, it suppresses the yeast-form in ex vivo mouse [1].

    价 格：￥电议型 号：T79931产 地：中国大陆

  • T79375NMDA receptor antagonist 8；化合物 NMDA receptor antagonist 8NMDA receptor antagonist 8

    Compound (R)-10a, an NMDA receptor antagonist, exhibits selectivity for the GluN2B subunit, possessing a Ki of 265 nM and an IC50 of 62 nM. This compound is utilized in research pertaining to neurodegenerative diseases [1].

    价 格：￥电议型 号：T79375产 地：中国大陆

  • T79374NMDA receptor antagonist 7；化合物 NMDA receptor antagonist 7NMDA receptor antagonist 7

    Compound (S)-10a, a GluN2B subunit-selective NMDA receptor antagonist, exhibits a K i of 93 nM and an IC 50 of 72 nM. It is potentially useful for research into neurodegenerative diseases [1].

    价 格：￥电议型 号：T79374产 地：中国大陆

  • T79273NMDA receptor antagonist 6；化合物 NMDA receptor antagonist 6NMDA receptor antagonist 6

    NMDA Receptor Antagonist 6 (Compound 13b) functions as an antagonist at the glycine-binding site of the NMDA receptor and demonstrates cytoneuroprotective efficacy. It safeguards PC12 cells from NMDA-induced damage and apoptosis [1].

    价 格：￥电议型 号：T79273产 地：中国大陆

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