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T5075Phytic acid dipotassium saltPhytic acid dipotassium salt,Inositol hexakisphosphate dipotassium salt,
Phytic acid exists in all eukaryotic cells. In plants, it is known to function as a [PO4]3- storage depot and precursor for other inositol phosphates and pyrophosphates. It can be used clinically as a complexing agent for removal of traces of heavy metal
价 格:¥电议型 号:T5075产 地:美洲
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T5213Lithium potassium acetyl phosphateLithium potassium acetyl phosphate,Acetylphosphoric acid,
Acetyl phosphate is a compound involved in taurine and hypotaurine metabolism as well as pyruvate metabolism. It is generated from sulfoacetaldehyde, converted to acetyl-CoA and acetate via phosphate acetyltransferase and acetate kinase respectively. It i
价 格:¥电议型 号:T5213产 地:美洲
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T5878β-Glycerol phosphate disodium salt pentahydrateβ-Glycerol phosphate disodium salt pentahydrate,BETA-
β-Glycerol phosphate disodium salt pentahydrate is a protein phosphatase inhibitor.
价 格:¥电议型 号:T5878产 地:美洲
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T5879TDCPPTDCPP,Fyrol FR 2,Tris(1,3-dichloroisopropyl)phosphate
TDCPP is classified under the chlorinated trialkyl organophosphate flame retardant (OPFR) group of compounds primarily utilized as additives in commercial products.
价 格:¥电议型 号:T5879产 地:美洲
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T6127Rucaparib PhosphateRucaparib Phosphate,PF-01367338 phosphate,AG-014699 phosphate
Rucaparib is an inhibitor of PARP (Ki: 1.4 nM for PARP1) that is used in clinical therapy to sensitize cancer cells to chemotherapy.
价 格:¥电议型 号:T6127产 地:美洲
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T6272Fosbretabulin DisodiumFosbretabulin Disodium,CA 4P,Combretastatin A4 disodium phosphate
Fosbretabulin (Combretastatin A4 Phosphate (CA4P)) Disodium, a water-soluble prodrug of Combretastatin A4 (CA4), is a microtubule-targeting agent that binds β-tubulin (Kd: 0.4 μM). Fosbretabulin Disodium inhibits the polymerization of tubulin (IC50: 2.4 μ
价 格:¥电议型 号:T6272产 地:美洲
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T6501Fludarabine PhosphateFludarabine Phosphate,F-ara-A (NSC 312887) Phosphate,fludara Phosphate
Fludarabine Phosphate is the phosphate salt of a fluorinated nucleotide antimetabolite analog of the antiviral agent vidarabine (ara-A) with antineoplastic activity. Fludarabine phosphate is rapidly dephosphorylated to 2-fluoro-ara-A and then phosphorylat
价 格:¥电议型 号:T6501产 地:美洲
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T83910S1PL-IN-31;化合物 S1PL-IN-31Sphingosine-1-Phosphate Lyase Inhibitor 31|||S1PL Inhibitor 31|||S1P Lyase
S1PL-IN-31 is a dual-function chemical compound acting as an inhibitor of sphingosine-1-phosphate (S1P) lyase with an IC50 value of 210 nM and as an antagonist of the Smoothened (Smo) receptor with an IC50 of 440 nM. Demonstrating therapeutic potential, this compound, at a dosage of 2 mg/kg per day, effectively mitigates cervical and thoracic lymphocyte infiltration and neuromuscular weakness in rats suffering from experimental autoimmune encephalomyelitis (EAE), a condition triggered by the MOG
价 格:¥电议型 号:T83910产 地:中国大陆
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T83908DXR Inhibitor 11a (free acid);化合物 DXR Inhibitor 11a (free acid)1-Deoxy-D-Xylulose-5-phosphate Reduct
DXR inhibitor 11a, with an IC50 of 0.11 ?M, effectively inhibits P. falciparum 1-deoxy-D-xylulose-5-phosphate reductoisomerase (DXR). It also hampers the growth of P. falciparum in isolated human erythrocytes, demonstrating an IC50 of 0.37 ?M.
价 格:¥电议型 号:T83908产 地:中国大陆
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T83885DXR Inhibitor 11a sodium;化合物 DXR Inhibitor 11a sodium1-Deoxy-D-Xylulose-5-Phosphate Reductoisomerase
DXR inhibitor 11a, with an IC50 value of 0.11 ?M, effectively inhibits P. falciparum 1-deoxy-D-xylulose-5-phosphate reductoisomerase (DXR). It also demonstrates significant activity against P. falciparum´s growth in isolated human erythrocytes, with an IC50 of 0.37 ?M.
价 格:¥电议型 号:T83885产 地:中国大陆
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T83880C18 Ceramide-1-phosphate (d18:1/18:0) ammonium;化合物 C18 Ceramide-1-phosphate (d18:1/18:0) ammoniumCer
C18 Ceramide-1-phosphate (d18:1/18:0) is a long-chain molecule identified in murine skin known to promote the migration of mouse bone marrow-derived multipotent stromal cells and human umbilical vein endothelial cells (HUVECs) at concentrations of 0.5 to 5 ?M. It exhibits elevated levels in CFPAC-1 pancreatic ductal adenocarcinoma cells compared to pancreatic cancer stem cells, and its myocardial concentration is heightened in Langendorff isolated perfused mouse hearts under an ex vivo ischemia
价 格:¥电议型 号:T83880产 地:中国大陆
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T83840Uridine-5’-O-(3-thiotriphosphate) sodium;化合物 Uridine-5’-O-(3-thiotriphosphate) sodiumUTP-γ-S;UTP-γ-S
Uridine-5´-O-(3-thiotriphosphate) (UTP-γ-S) is a hydrolysis-resistant UTP derivative and an agonist of the purinergic P2Y2 receptor. It effectively induces inositol phosphate formation in 1321N1 astrocytoma cells harboring the human P2Y2 receptor (EC50 = 240 nM) and stimulates chloride secretion in a dose-dependent manner in primary nasal epithelial cells from cystic fibrosis patients. Moreover, UTP-γ-S prompts vasoconstriction in isolated human coronary arteries (EC50 = 25.1 ?M).
价 格:¥电议型 号:T83840产 地:中国大陆
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T83839Uridine 5’-methylenediphosphate sodium;化合物 Uridine 5’-methylenediphosphate sodiumα,β-methylene UDP||
Uridine 5’-methylenediphosphate (UMP-CP), a hydrolytically stable derivative of UDP and agonist of the purinergic P2Y14 receptor, exhibits selective inhibition of cAMP production in cells expressing human P2Y14 compared to those expressing human P2Y6, with EC50 values of 11 nM and 339 nM, respectively.
价 格:¥电议型 号:T83839产 地:中国大陆
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T83838Sp-Thymidine-5’-O-(1-thiotriphosphate) sodium;化合物 Sp-Thymidine-5’-O-(1-thiotriphosphate) sodiumSp-TT
Sp-Thymidine-5´-O-(1-thiotriphosphate) (Sp-TTP-α-S), an isomer of the sulfur-containing nucleotide derivative TTP-α-S, exhibits affinity for HIV-1 reverse transcriptase with dissociation constants (Kds) of 2.88, 4.23, and 20.21 ?M in the presence of magnesium, manganate, and cobalt, respectively. Additionally, Sp-TTP-α-S effectively inhibits the enzyme deoxynucleoside triphosphate triphosphohydrolase SAMHD1 with an inhibition constant (Ki) of 46 nM.
价 格:¥电议型 号:T83838产 地:中国大陆
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T83837Rp-Thymidine-5’-O-(1-thiotriphosphate) sodium;化合物 Rp-Thymidine-5’-O-(1-thiotriphosphate) sodiumRp-dT
Rp-Thymidine-5´-O-(1-thiotriphosphate) (Rp-TTP-α-S), an isomer of the sulfur-containing nucleotide derivative TTP-α-S, selectively interacts with HIV-1 reverse transcriptase, exhibiting dissociation constants (Kds) of 45.7, 27.32, and 39.44 ?M in the presence of magnesium, manganate, and cobalt, respectively.
价 格:¥电议型 号:T83837产 地:中国大陆
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T83834Sp-Guanosine-5’-O-(1-thiotriphosphate) sodium;化合物 Sp-Guanosine-5’-O-(1-thiotriphosphate) sodiumSp-GT
Sp-Guanosine-5´-O-(1-thiotriphosphate) (Sp-GTP-α-S), an isomer of the sulfur-containing nucleotide derivative GTP-α-S, demonstrates the ability to bind tubulin and facilitate microtubule assembly in cell-free assays at a concentration of 20 mM.
价 格:¥电议型 号:T83834产 地:中国大陆
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T83833Rp-2’-Deoxyuridine-5’-O-(1-thiotriphosphate) sodium;化合物 Rp-2’-Deoxyuridine-5’-O-(1-thiotriphosphate)
Rp-2´-Deoxyuridine-5´-O-(1-thiotriphosphate) (Rp-dUTP-α-S), a sulfur-containing nucleotide isomer and purinergic P2Y2 receptor agonist, preferentially promotes inositol phosphate accumulation in 1321N1 astrocytoma cells with P2Y2 receptors (EC50 = 12.5 ?M) compared to those expressing P2Y4 receptors at a concentration of 10 ?M.
价 格:¥电议型 号:T83833产 地:中国大陆
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T83831Sp-2’-Deoxyguanosine-5’-O-(1-thiotriphosphate) sodium;化合物 Sp-2’-Deoxyguanosine-5’-O-(1-thiotriphosph
Sp-2´-Deoxyguanosine-5´-O-(1-thiotriphosphate), a sulfur-containing isomer of 2´-deoxyguanosine-5´-O-triphosphate (dGTP), functions as an inhibitor of the deoxynucleoside triphosphate triphosphohydrolase SAMHD1, with an inhibitory constant (Ki) of 820 nM.
价 格:¥电议型 号:T83831产 地:中国大陆
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T838292’-Deoxy-1,N6-ethenoadenosine-5’-O-triphosphate sodium;化合物 2’-Deoxy-1,N6-ethenoadenosine-5’-O-tripho
2´-Deoxy-1,N6-ethenoadenosine-5´-O-triphosphate (ε-dATP), a fluorescent derivative of 2’-deoxyadenosine-5’-O-triphosphate (dATP), promotes sister chromatid exchange in stimulated primary mouse spleen T- and B lymphocytes with LPS or concanavalin A at concentrations of 50 to 150 ?M. Utilized in ambiguous base pairing investigations within vinyl chloride-induced mutagenesis research, ε-dATP, along with its related compound ε-ATP—which exhibits an emission peak at 415 nm after being exc
价 格:¥电议型 号:T83829产 地:中国大陆
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T83828Sp-2’-Deoxycytidine-5’-O-(1-thiotriphosphate) sodium;化合物 Sp-2’-Deoxycytidine-5’-O-(1-thiotriphosphat
Sp-2´-Deoxycytidine-5´-O-(1-thiotriphosphate) (Sp-dCTP-α-S), an isomer of the sulfur-containing nucleotide derivative dCTP-α-S, functions as an inhibitor of the deoxynucleoside triphosphate triphosphohydrolase SAMHD1, with an inhibition constant (Ki) of 6.3 ?M.
价 格:¥电议型 号:T83828产 地:中国大陆