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T15823LYPLAL1-IN-1;化合物 T15823LYPLAL1-IN-1
LYPLAL1-IN-1 is a selective covalent small-molecule inhibitor of Lysophospholipase-like 1 (IC50: 0.006 μM). LYPLAL1-IN-1 also enhances glucose production.
价 格:¥电议型 号:T15823产 地:中国大陆
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T15782Lp-PLA2-IN-1;化合物Lp-PLA2 -IN-1Lp-PLA2 inhibitor 1|||Lp-PLA2 -IN-1;Lp-PLA2 inhibitor 1|||Lp-PLA2 -IN-1
Lp-PLA2-IN-1 (Lp-PLA2 inhibitor 1) suppresses Lp-PLA2 activity processes for their preparation. Lp-PLA2-IN-1 (Lp-PLA2 inhibitor 1) also inhibits to compositions containing them and to their use in the treatment of diseases associated with the activity of Lp-PLA2, for example, atherosclerosis, Alzheimer´s disease.
价 格:¥电议型 号:T15782产 地:中国大陆
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T15661Kif15-IN-1;化合物 T15661Kif15-IN-1
Kif15-IN-1, a mitotic Kinesin family member 15 (Kif15) inhibitor, is utilized in the study of cellular proliferative diseases.
价 格:¥电议型 号:T15661产 地:中国大陆
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T15660KHK-IN-1;化合物KHK-IN-1KHK-IN-8|||Ketohexokinase inhibitor 8;KHK-IN-8|||Ketohexokinase inhibitor 8
KHK-IN-1 (KHK-IN-8) is a selective and cell membrane permeable inhibitor of ketohexokinase (KHK, IC50=12 nM; F=34%). KHK-IN-1 inhibits F1P production in HepG2 cell lysates with IC50 of 400 nM. KHK-IN-1 has potential for the study of obesity and diabetes.
价 格:¥电议型 号:T15660产 地:中国大陆
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T15659KHK-IN-1 hydrochloride;化合物 T15659KHK-IN-1 hydrochloride
KHK-IN-1 hydrochloride is a potent inhibitor of ketohexokinase (KHK) (IC50: 12 nM). In the ATP-binding region of KHK, KHK-IN-1 hydrochloride interacts with Asp-27B.
价 格:¥电议型 号:T15659产 地:中国大陆
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T15650KDM5A-IN-1;KDM5A抑制剂1KDM5A-IN-1
KDM5A-IN-1 is an orally available, potent and selective inhibitor of the pan-histidine lysine demethylase 5 KDM5, inhibiting KDM5A, KDM5B, and KDM5C with IC50 values of 45 nM, 56 nM, and 55 nM, respectively.KDM5A-IN-1 inhibits PC9 H3K4Me3, and may be useful in cancer research.
价 格:¥电议型 号:T15650产 地:中国大陆
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T15649KDM5-IN-1;化合物KDM5-IN-1KDM5-IN-1
KDM5-IN-1 is an effective and selective inhibitor of KDM5 with an IC50 of 15.1 nM.
价 格:¥电议型 号:T15649产 地:中国大陆
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T15607JAK3-IN-1;化合物 T15607JAK3-IN-1
JAK3-IN-1 is a selective and orally active JAK3 inhibitor (IC50: 4.8 nM). JAK3-IN-1 displays over 180-fold more selective for JAK3 than JAK1 (IC50: 896 nM) and JAK2 (IC50: 1050 nM).
价 格:¥电议型 号:T15607产 地:中国大陆
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T15482HIF-2α-IN-1;HIF-2α抑制剂1HIF-2α-IN-1
HIF-2α-IN-1 is a potent HIF-2α inhibitor with IC50 values less than 500 nM.
价 格:¥电议型 号:T15482产 地:中国大陆
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T15413GPR120 Agonist 3;化合物GPR120 Agonist 3FFAR|||GPR120-IN-1|||GPR120-IN-1|||GPR120 Agonist 3|||GPR120 Ago
GPR120 Agonist 3 (GPR120-IN-1) is a selective agonist of Gpr120 ( logEC50: -7.62).
价 格:¥电议型 号:T15413产 地:中国大陆
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T15274FEN1-IN-1;化合物FEN1-IN-1LNT-1;LNT-1
FEN1-IN-1 (LNT-1) is an inhibitor of flap endonuclease 1 (FEN1). FEN1-IN-1 binds to the active site of FEN1. It partly achieves inhibition by the co-ordination of Mg2+ ions.
价 格:¥电议型 号:T15274产 地:中国大陆
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T15109DGAT1-IN-1;化合物DGAT1-IN-1DGAT1-IN-1
DGAT1-IN-1 is a potent inhibitor of diacylglycerol O- acyltransferase type 1(DGAT1, IC50 of < 10 nM).
价 格:¥电议型 号:T15109产 地:中国大陆
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T14860CaMKII-IN-1;化合物CaMKII-IN-1CaMKII-IN-1
CaMKII-IN-1 is a potent and highly selective inhibitor of CaMKII (IC50 = 63 nM). CaMKII-IN-1 exhibited more than 100-fold higher selectivity for CaMKII over CaMKIV, MLCK, p38a, Akt1, and PKC.
价 格:¥电议型 号:T14860产 地:中国大陆
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T14763BoNT-IN-1;化合物 T14763BoNT-IN-1
BoNT-IN-1 is a potent Botulinum neurotoxin A light chain (BoNTA LC) inhibitor(IC50 : 0.9 uM).
价 格:¥电议型 号:T14763产 地:中国大陆
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T14692BMX-IN-1;化合物BMX-IN-1BMX kinase inhibitor;BMX kinase inhibitor
BMX-IN-1 (BMX kinase inhibitor) is a selective inhibitor of bone marrow tyrosine kinase on chromosome X (BMX, IC50 = 8 nM) and the related Bruton’s tyrosine kinase (BTK, IC50 = 10.4 nM), but BMX-IN-1 is more than 47-656 fold less potent against Blk, JAK3, EGFR, Itk, or Tec activity.
价 格:¥电议型 号:T14692产 地:中国大陆
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T14352Autotaxin-IN-1;化合物 T14352Autotaxin-IN-1
Autotaxin-IN-1 is a potent autotaxin inhibitor, which has favorable potency (IC50=2.2 nM), PK properties, and a robust PK/PD relationship and it is used in treatment of osteoarthritis pain[1].
价 格:¥电议型 号:T14352产 地:中国大陆
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T14283amyloid P-IN-1;化合物amyloid P-IN-1amyloid P IN 1|||amyloid P-IN-1|||amyloid PIN1;amyloid P IN 1|||amyl
amyloid P-IN-1 can be used in studies about diseases with depletion of serum amyloid P components such as Alzheimer´s disease, amyloidosis, osteoarthritis, and type 2 diabetes mellitus.
价 格:¥电议型 号:T14283产 地:中国大陆
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T14175Aldose reductase-IN-1;化合物Aldose reductase-IN-1AT-001|||Caficrestat;AT-001|||Caficrestat
Aldose reductase-IN-1 (AT-001) is a aldose reductase inhibitor (IC50: 28.9 pM).
价 格:¥电议型 号:T14175产 地:中国大陆
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T14152Akt1 and Akt2-IN-1;化合物 T14152Akt1 and Akt2-IN-1
Akt1 and Akt2-IN-1 is an allosteric inhibitor of Akt1 (IC50=3.5 nM) and Akt2 (IC50=42 nM). It has potent and balanced activity.
价 格:¥电议型 号:T14152产 地:中国大陆
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T14151AKR1C1-IN-1;化合物AKR1C1-IN-1AKR1C1-IN-1
AKR1C1-IN-1 is a human 20α-hydroxysteroid dehydrogenase (AKR1C1) inhibitor (Ki: 4 nM for AKR1C1).
价 格:¥电议型 号:T14151产 地:中国大陆