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T6158LDN-193189 HCl；化合物LDN-193189 HClLDN193189 Hydrochloride；LDN193189 Hydrochloride
LDN-193189 HCl (LDN193189 Hydrochloride) is a selective BMP type I receptor kinases inhibitor.
价 格：￥电议型 号：T6158产 地：中国大陆
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T61558HBV-IN-21；化合物 HBV-IN-21HBV-IN-21
HBV-IN-21 (Compound II-8b) is a potent inhibitor of HBV DNA replication, exhibiting an IC50 of 2.2 μM. It demonstrates a favorable binding affinity (K D = 60.0 μM) for the HBV 4 capsid protein, thereby enabling effective interaction [1].
价 格：￥电议型 号：T61558产 地：中国大陆
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T61540F15845；化合物 F15845F15845
F 15845 is a potent and persistent blocker of the sodium current. It possesses cardioprotective properties and exhibits both anti-ischemic activity and short- and long-term cardioprotection following myocardial infarction. Furthermore, F 15845 finds utility in the investigation of myocardial functional impairment [1].
价 格：￥电议型 号：T61540产 地：中国大陆
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T6148CX-6258 hydrochloride；化合物CX-6258 HClCX-6258 HCl|||Pim-Kinase Inhibitor X；CX-6258 HCl|||Pim-Kinase In
CX-6258 hydrochloride (Pim-Kinase Inhibitor X) is an effective, orally efficacious Pim1/2/3 kinase inhibitor (IC50: 5/25/16 nM).
价 格：￥电议型 号：T6148产 地：中国大陆
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T61458HIF-PHD-IN-2；化合物 HIF-PHD-IN-2HIF-PHD-IN-2
HIF-PHD-IN-2 (compound 25) is a highly effective PHD inhibitor, displaying IC50 values below 100 nM for PHD1, PHD2, and PHD3 [1].
价 格：￥电议型 号：T61458产 地：中国大陆
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T61358AKN-028 acetate；化合物 AKN-028 acetateAKN-028 acetate
AKN-028 acetate, a novel tyrosine kinase (TK) inhibitor, is a potent, orally active FMS-like receptor tyrosine kinase 3 (FLT3) inhibitor with an IC 50 value of 6 nM. AKN-028 acetate inhibits FLT3 autophosphorylation. AKN-028 acetate induces dose-dependent cytotoxic response (mean IC 50 =1 μM). AKN-028 acetate induces apoptosis by activation of caspase 3. AKN-028 acetate can be used in research of acute myeloid leukemia (AML) [1].
价 格：￥电议型 号：T61358产 地：中国大陆
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T61258HFI-419；化合物 HFI-419HFI-419
HFI-419 is a potent inhibitor of insulin-regulated aminopeptidase (IRAP) with a K i value of 0.48 μM. It is utilized in research pertaining to cognitive and memory impairments, including Alzheimer´s disease, brain trauma, and stroke [1].
价 格：￥电议型 号：T61258产 地：中国大陆
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T61158Anti-infective agent 5；化合物 Anti-infective agent 5Anti-infective agent 5
Anti-infective agent 5 (compound 74) is an orally active inhibitor of Trypanosoma cruzi exhibiting an IC50 value of 0.10 μM. In addition to its potent inhibitory effect, anti-infective agent 5 demonstrates efficacy in reducing parasite burden in vivo. Consequently, this compound holds promising potential for research pertaining to infection. [1]
价 格：￥电议型 号：T61158产 地：中国大陆
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T61122ZINC12409120；化合物ZINC12409120R-4584；R-4584
ZINC12409120 (R-4584) is a selective ERK inhibitor.ZINC12409120 inhibits ERK with an IC50 of 5.0 μM.ZINC12409120 inhibits ERK activity by interfering with FGF23:α-Klotho interaction.
价 格：￥电议型 号：T61122产 地：中国大陆
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T61058JMI-105；化合物 JMI-105JMI-105
JMI-105 has the potential as an antimalarial agent. JMI-105 is a potent inhibitor of Plasmodium falciparum falcipain-2 protease (PfFP-2) that inhibits the P. falciparum strains CQ S (3D7) and CQ R (RKL-9) growth with IC 50 values of 8.8 μM and 14.3 μM. In a murine model with P. berghei ANKA infection, JMI-105 significantly decreases parasitemia and prolonged host survival [1].
价 格：￥电议型 号：T61058产 地：中国大陆
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T6103VS-5584；化合物VS5584SB2343|||VS 5584|||VS5584；SB2343|||VS 5584|||VS5584
VS-5584 (SB2343) is a pan-PI3K/mTOR kinase inhibitor.
价 格：￥电议型 号：T6103产 地：中国大陆
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T60984TH588 hydrochloride；化合物 TH588 hydrochlorideTH588 hydrochloride
TH588 hydrochloride is first-in-class inhibitor of nudix hydrolase family that selectively and effectively bind and inhibit the MTH1 with IC50 value of 5 nM.
价 格：￥电议型 号：T60984产 地：中国大陆
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T6097GNF-5837；化合物GNF5837GNF 5837；GNF 5837
GNF-5837 is a specific, and orally bioavailable pan-TRK inhibitor for TrkA/TrkB (IC50: 8/12 nM).
价 格：￥电议型 号：T6097产 地：中国大陆
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T60959As-358 hydrochloride；化合物 As-358 hydrochlorideAs-358 hydrochloride
As-358 (hydrochloride) shows well in vivo safety as well as inhibits Ebola virus and Marburg virus with IC 50 values of 9.1 μM and 18.1 μM [1].
价 格：￥电议型 号：T60959产 地：中国大陆
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T60858MOPIPP；化合物 MOPIPPMOPIPP
MOPIPP is a novel indolebased chalcone that can cross the blood-brain barrier. MOPIPP inhibits the tumor progression agaisnt glioblastoma cells. MOPIPP induces cellular vacuolization as well as increases autophagosomes numbers. MOPIPP also triggers methuosis and distrupts glucose uptake and glycolytic metabolism [1] [2] [3].
价 格：￥电议型 号：T60858产 地：中国大陆
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T60758Tubulin polymerization-IN-36；化合物 Tubulin polymerization-IN-36Tubulin polymerization-IN-36
Tubulin polymerization-IN-36 is able to be used in cancer research, for example, lymphomas. Tubulin polymerization-IN-36 binds to the colchicine site of tubulin and inhibits colchicine binding, that is an inhibitor of tubulin polymerization with IC50 of 2.8 μΜ[1].
价 格：￥电议型 号：T60758产 地：中国大陆
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T60658hMAO-B/MB-COMT-IN-2；化合物 hMAO-B/MB-COMT-IN-2hMAO-B/MB-COMT-IN-2
hMAO-B/MB-COMT-IN-2 is a dual inhibitor of MAO-B/MB-COMT with IC 50s of 4.27 μΜ and 2.69 μΜ for hMAO-B and MB-COMT, respectively. hMAO-B/MB-COMT-IN-2 protects cells from oxidative damage that can be used in the neurodegeneration disease research, for example, Parkinson’s Disease (PD) [1].
价 格：￥电议型 号：T60658产 地：中国大陆
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T60623As-358；化合物 As-358As-358
As-358 has inhibitory effects against Ebola virus (IC50 = 47.5 μM) and Marburg virus (IC50 = 3.7 μM) [1].
价 格：￥电议型 号：T60623产 地：中国大陆
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T60589Cdc7-IN-17；化合物 Cdc7-IN-17Cdc7-IN-17
Cdc7-IN-17 is a potent inhibitor of CDC7 with an IC 50 of <10 μM that can be used in cancer research [1].
价 格：￥电议型 号：T60589产 地：中国大陆
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T60588T761-0184；化合物 T761-0184T761-0184
T761-0184 is a potent antagonist of α7 nicotinic receptor (nAChR) [1].
价 格：￥电议型 号：T60588产 地：中国大陆
