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T15621Rilematovir；化合物RilematovirJNJ-53718678|||JNJ-678；JNJ-53718678|||JNJ-678
Rilematovir (JNJ-678) is an inhibitor of fusion protein with antiviral activity and low cytotoxicity. Rilematovir can be used in studies about respiratory syncytial virus treatment.
价 格：￥电议型 号：T15621产 地：中国大陆
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T15619JNJ-46778212；化合物 JNJ-46778212VU 0409551；VU 0409551
JNJ-46778212 (VU 0409551) is a selective and potent mGlu5 allosteric modulator (EC50: 260 nM) for the study of neurodissection.
价 格：￥电议型 号：T15619产 地：中国大陆
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T15618JNJ-46281222；化合物 T15618JNJ-46281222
JNJ-46281222 is an metabotropic glutamate (mGlu) 2-selective, highly potent PAM (positive allosteric modulator). It has nanomolar affinity (Kd = 1.7 nM) and a high modulatory potency (pEC50 = 7.71).
价 格：￥电议型 号：T15618产 地：中国大陆
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T15617JNJ-38877618；化合物JNJ-38877618OMO-1；OMO-1
JNJ-38877618 (OMO-1) is an effective and highly selective inhibitor of Met kinase (IC50s: 2 and 3 nM for wild type and mutant Met, respectively).
价 格：￥电议型 号：T15617产 地：中国大陆
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T15616JNJ-10198409；化合物JNJ-?10198409JNJ-?10198409；3-氟-N-(6,7-二甲氧基-2,4-二氢茚并[1,2-C〕吡唑-3-基苯基胺|||JNJ-?10198409
JNJ- 10198409 is a relatively selective and ATP competitive PDGF-RTK inhibitor (IC50=2 nM). JNJ-10198409 has good activity against PDGFR-β kinase (IC50=4.2 nM) and PDGFR-α kinase (IC50=45 nM). It is a dual-mechanism, antiangiogenic, and tumor cell antiproliferative agent.
价 格：￥电议型 号：T15616产 地：中国大陆
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T15615JND3229；化合物JND3229JND3229
JND3229 is a reversible EGFRC797S inhibitor with IC50 values of 5.8, 6.8 and 30.5 nM for EGFRL858R/T790M/C797S, EGFRWT and EGFRL858R/T790M, respectively. JND3229 has good anti-proliferative activity and can effectively inhibit tumour growth in vivo. JND3229 can be used in cancer research, especially in non-small cell carcinoma.
价 格：￥电议型 号：T15615产 地：中国大陆
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T15614JJKK 048；化合物JJKK 048JJKK 048
JJKK 048 is a potent and selective MAGL inhibitor.
价 格：￥电议型 号：T15614产 地：中国大陆
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T15613JHU-083；化合物 T15613JHU-083
JHU-083 is a selective glutaminase antagonist. JHU-083 blocks glutaminase activity in brain CD11b+ cells. JHU-083 also experimental cerebral malaria (ECM) resulting in a net decrease of glutamate levels in the animals.
价 格：￥电议型 号：T15613产 地：中国大陆
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T15612JH-VIII-157-02；化合物JH-VIII-157-02JH-VIII-157-02
JH-VIII-157-02 is an inhibitor of ALK and inhibits echinoderm microtubule-associated protein-like 4-ALK (EML4-ALK) with IC50s of 2 nM for EML4-ALK G1202R, EML4-ALKwt, EML4-ALK C1156Y, EML4-ALK F1174L, and EML4-ALK F1174L.
价 格：￥电议型 号：T15612产 地：中国大陆
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T15611JH-RE-06；化合物JH-RE-06JH-RE-06
JH-RE-06 disrupts mutagenic translesion synthesis (TLS) by preventing the recruitment of mutagenic POLζ. JH-RE-06 is an effective REV1-REV7 interface inhibitor (IC50=0.78 μM; Kd=0.42 μM), which targets REV1 that interacts with the REV7 subunit of POLζ. JH-RE-06 also improves chemotherapy.
价 格：￥电议型 号：T15611产 地：中国大陆
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T15610JFD00244化合物 T15610JFD 00244|||JFD-00244|||JFD00244
JFD00244 is an inhibitor of sirtuin 2 (SIRT2). It has an anti-tumor effect.
价 格：￥电议型 号：T15610产 地：中国大陆
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T15609JC-1；化合物JC-1CBIC2；CBIC2
JC-1 (CBIC2) is a fluorescent lipophilic carbocyanine dye. It has been used to measure mitochondrial membrane potential. JC 1 can be used in a probe for measuring mitochondrial membrane potential by flow cytometry.
价 格：￥电议型 号：T15609产 地：中国大陆
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T15608Jarin-1；化合物Jarin-1Jarin-1
Jarin-1 is a jasmonic acid-amido synthetase (JAR1) inhibitor (IC50: 3.8 μM). Jarin-1 specific suppresses bioactive JA biosynthesis in Arabidopsis and other plants.
价 格：￥电议型 号：T15608产 地：中国大陆
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T15607JAK3-IN-1；化合物 T15607JAK3-IN-1
JAK3-IN-1 is a selective and orally active JAK3 inhibitor (IC50: 4.8 nM). JAK3-IN-1 displays over 180-fold more selective for JAK3 than JAK1 (IC50: 896 nM) and JAK2 (IC50: 1050 nM).
价 格：￥电议型 号：T15607产 地：中国大陆
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T15606JAK1-IN-4；化合物 T15606JAK1-IN-4
JAK1-IN-4 is a selective JAK1 inhibitor (IC50s: 85 nM, 12.8 μM and >30 μM for JAK1, JAK2, and JAK3, respectively). JAK1-IN-4 inhibits STAT3 phosphorylation in NCI-H 1975 cells (IC50, 227 nM).
价 格：￥电议型 号：T15606产 地：中国大陆
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T15485HJC0197；化合物HJC0197HJC0197
HJC0197 selectively blocks cAMP-induced Epac activation. HJC0197 is an effective exchange protein. Which straightly activated by cAMP (Epac) antagonist (IC50=5.9 μM for Epac2).
价 格：￥电议型 号：T15485产 地：中国大陆
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T15336Fonadelpar；化合物 T15336SJP0035|||Fonadelpar|||SJP-0035|||NPS005|||SJP 0035|||NPS-005|||NPS-005|||Fonad
Fonadelpar is an agonist of PPARδ. It also is used in the research of neuroparalytic keratopathy.
价 格：￥电议型 号：T15336产 地：中国大陆
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T15219Enarodustat；化合物EnarodustatHIF/HIF Prolyl-Hydroxylase|||HIFs|||inhibit|||JTZ951|||HIF-PH|||Hypoxia-in
Enarodustat (JTZ-951) is an orally active factor inhibitor of prolyl hydroxylase (EC50: 0.22 μM) and has the potential for renal anemia treatment.
价 格：￥电议型 号：T15219产 地：中国大陆
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T15200Edotecarin；化合物 T15200PF 804950|||J 107088；PF 804950|||J 107088
Edotecarin is a potent topoisomerase I inhibitor. It can decrease single-strand DNA cleavage (IC50: 50 nM).
价 格：￥电议型 号：T15200产 地：中国大陆
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T15199Edicotinib；化合物EdicotinibJNJ-527|||JNJ-40346527；JNJ-527|||JNJ-40346527
Edicotinib (JNJ-527) is a brain penetrant and orally active inhibitor of the colony-stimulating factor-1 receptor (IC50: 3.2 nM). It shows less inhibitory effects on KIT and FLT3 (IC50: 20 nM and 190 nM). It has the potential for Alzheimer´s disease and rheumatoid arthritis treatment.
价 格：￥电议型 号：T15199产 地：中国大陆
