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  • T60586F8-S40；化合物 F8-S40F8-S40

    F8-S40 is a SARS-CoV-2 main protease inhibitor (IC 50 = 10.88 μM) [1].

    价 格：￥电议型 号：T60586产 地：中国大陆

  • T60585RSK2-IN-2；化合物 RSK2-IN-2RSK2-IN-2

    RSK2-IN-2 (Compound 25) is a reversible covalent inhibitor of the RPS6KA3 ( RSK2 ) kinase which also inhibits MSK1, MSK2, and RSK3 [1].

    价 格：￥电议型 号：T60585产 地：中国大陆

  • T60584Cimetidine hydrochloride；化合物 Cimetidine hydrochlorideCimetidine hydrochloride

    Cimetidine (SKF-92334) hydrochloride is an orally active and inverse histamine H2 receptor antagonist with a Ki of 0.6 μM. Cimetidine hydrochloride shows anti-cancer and anti-inflammatory activity. Cimetidine hydrochloride is a gastric acid reducer that can be used in the research of duodenal and gastric ulcers[1] [2] [5].

    价 格：￥电议型 号：T60584产 地：中国大陆

  • T60583CDK1/2/4-IN-1；化合物 CDK1/2/4-IN-1CDK1/2/4-IN-1

    CDK1/2/4-IN-1 (compound 3a) is a potent inhibitor of CDK with IC 50 values of 1.47, 0.78 and 0.87 μM for CDK1, CDK2 and CDK4, respectively. CDK1/2/4-IN-1 can be used in cancer research. CDK1/2/4-IN-1 arrests cell cycle at G2/M phase and induces apoptosis. CDK1/2/4-IN-1 elevates the level of Bax, caspase-3, and P53 and decreases the level of Bcl-2 [1].

    价 格：￥电议型 号：T60583产 地：中国大陆

  • T60582Antibacterial agent 74；化合物 Antibacterial agent 74Antibacterial agent 74

    Antibacterial agent 74 (compound 36) has anti-Salmonella activity [1].

    价 格：￥电议型 号：T60582产 地：中国大陆

  • T60581Alkannin；化合物 AlkanninAlkannin

    Alkannin is a potent and specific tumor-specific pyruvate kinase-M2 (PKM2) inhibitor that does not inhibit PKM1 and pyruvate kinase-L (PKL). Alkannin is a potential anticancer agent [1].

    价 格：￥电议型 号：T60581产 地：中国大陆

  • T60580A1AR antagonist 2；化合物 A1AR antagonist 2A1AR antagonist 2

    A1AR antagonist 2 (compound 18h) is a potent antagonist of the A1 adenosine receptor (AR). A1AR antagonist 2 has Ki values of 1.49, 10.2, and 50.1 nM for hA 1, hA 2A, and hA 2B, respectively [1].

    价 格：￥电议型 号：T60580产 地：中国大陆

  • T6058LY2886721；化合物LY2886721LY2886721

    LY2886721, a BACE inhibitor, is used for the therapy of Alzheimer´s Disease.

    价 格：￥电议型 号：T6058产 地：中国大陆

  • T60558NSC 694623；化合物NSC 694623NSC 694623

    NSC 694623 is a potent histone acetyltransferase (HAT) inhibitor with IC50 of 15.9 μM against recombinant HAT p300/CBP associated factor (PCAF). NSC 694623 shows anti-proliferative activity against some cancer cells, which can be used for anti-cancer research.

    价 格：￥电议型 号：T60558产 地：中国大陆

  • T60458NS2B/NS3-IN-4；化合物 NS2B/NS3-IN-4NS2B/NS3-IN-4

    Compound 34e (NS2B/NS3-IN-4) is an allosteric inhibitor of the DENV2 and ZIKV NS2B/NS3 proteases, exhibiting IC50 values of 0.69 ?M for DENV2 and 1.04 ?M for ZIKV NS2B/NS3 proteases [1].

    价 格：￥电议型 号：T60458产 地：中国大陆

  • T60438LPXS-6302 hydrochloride；化合物PXS-6302盐酸盐PXS-6302 hydrochloride （2584947-54-4 Free base）；PXS-6302 hydroc

    PXS-6302 hydrochloride is a potent irreversible lysine oxidase (LOX) inhibitor, inhibiting Bovine LOX, rh LOXL1, rh LOXL2, rh LOXL3, and rh LOXL4 with IC50 of 3.7 μM, 3.4 μM, 0.4 μM, 1.5 μM, and 0.3 μM, respectively. PXS-6302 hydrochloride penetrates easily through the skin and is able to reduce collagen accumulation, significantly improving the appearance of scars.

    价 格：￥电议型 号：T60438L产 地：中国大陆

  • T60358sEH inhibitor-7；化合物sEH inhibitor-7sEH inhibitor-7

    sEH inhibitor-7 is a soluble epoxide hydrolase (sEH) inhibitor that inhibits sEH in human and mouse with IC 50 s of 6.2 μM and 0.15 μM, respectively. sEH inhibitor-7 is associated with anti-inflammatory active molecules.

    价 格：￥电议型 号：T60358产 地：中国大陆

  • T60169BLU0588；化合物BLU0588BLU0588

    BLU0588 is a selective PRKACA inhibitor. BLU0588 inhibits PRKACA catalytic activity with a half-maximal inhibitory concentration (IC50) of 1 nM.

    价 格：￥电议型 号：T60169产 地：中国大陆

  • T60158PBRM1-BD2-IN-3；化合物PBRM1-BD2-IN-3PBRM1-BD2-IN-3

    PBRM1-BD2-IN-3 (compound 12) is a potent inhibitor of PBRM1-BD2, exhibiting an IC50 value of 1.1 μM, and is utilized in anticancer research.

    价 格：￥电议型 号：T60158产 地：中国大陆

  • T60095CCF0058981；化合物CCF0058981CCF0058981

    CCF0058981 (CCF981) is a 3-chlorophenyl analogue, serving as a noncovalent inhibitor of SARS-CoV-2 3CL pro (SC2), demonstrating potent activity with an IC50 of 68 nM. It also exhibits inhibitory effects against SARS-CoV-1 3CL pro (SC1) with an IC50 of 19 nM, highlighting its antiviral efficacy and potential in COVID-19 research [1].

    价 格：￥电议型 号：T60095产 地：中国大陆

  • T60058methyl 4-(2-amino-5-(4-((dimethylamino)methyl)thiophen-2-yl)pyridin-3-yl)-2-((5,5,5-trifluoropent-3-

    methyl4-(2-amino-5-(4-((dimethylamino)methyl)thiophen-2-yl)pyridin-3-yl)-2-((5,5,5-trifluoropent-3-yn-2-yl)oxy)benzoate is a useful compound for the synthesis of a variety of organic compounds.

    价 格：￥电议型 号：T60058产 地：中国大陆

  • T5S2358Dehydrocorydaline；脱氢紫堇碱Dehydrocorydalin|||13-Methylpalmatine；Dehydrocorydalin|||脱氢紫堇碱|||13-Methylpal

    1. Dehydrocorydaline (13-Methylpalmatine) exerts anti-metastatic potential via suppression of MMPs and Bcl-2 signaling in NSC-LC cells. 2. Dehydrocorydaline stimulates p38 MAPK activation, which can enhance heterodimerization of MyoD and E proteins, thus resulting in MyoD activation and myoblast differentiation. 3. Dehydrocorydaline shows antiplatelet effects, it inhibits thrombin-induced platelet aggregation in a low dose ( IC50= 34.914 ug/mL). 4. Dehydrocorydaline has anti-inflammatory and ant

    价 格：￥电议型 号：T5S2358产 地：中国大陆

  • T5S1058Triptonide；雷公藤内酯酮PG 492|||NSC 165677；雷公藤内酯酮|||PG 492|||NSC 165677

    1. Triptonide (PG 492) is effective in the treatment of autoimmune diseases and has potent antileukemic and antitumor activities. 2. Triptonide possesses anti-inflammatory activity, upregulate the expression of IL-37, and this expression was suppressed by ERK1/2 and p38 MAPK inhibitors.

    价 格：￥电议型 号：T5S1058产 地：中国大陆

  • T5S0658Corynoxine柯诺辛柯诺辛|||柯诺辛碱

    Corynoxine is a tetracyclic oxindole alkaloid isolated from Uncaria macrophylla. It is an autophagy enhancer that promotes α-synuclein clearance through the Akt/mTOR pathway.

    价 格：￥电议型 号：T5S0658产 地：中国大陆

  • T5S0581Sec-O-Glucosylhamaudol；亥茅酚苷Hamaudol 3-glucoside；亥茅酚苷|||Hamaudol 3-glucoside

    Sec-O-Glucosylhamaudol (Hamaudol 3-glucoside) has anti-inflammatory effect through regulation of p38 Mitogen-Activated Protein Kinase in Lipopolysaccharide-stimulated RAW264.7 cell line. Intrathecal Sec-O-Glucosylhamaudol has a very strong antinociceptive effect in the formalin test and it seems the effect is related to an opioid receptor.

    价 格：￥电议型 号：T5S0581产 地：中国大陆

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