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T15190L(S,R,S)-AHPC-PEG4-NH2；化合物T15190LVHL Ligand-Linker Conjugates 4|||E3 ligase Ligand-Linker Conjugates
(S,R,S)-AHPC-PEG4-NH2 (VHL Ligand-Linker Conjugates 4) is a synthetic E3 ligase ligand-linker conjugate comprising a VHL ligand based on (S,R,S)-AHPC and a 4-unit PEG linker.
价 格：￥电议型 号：T15190L产 地：中国大陆
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T15190(S,R,S)-AHPC-PEG4-NH2 hydrochloride；化合物 T15190E3 ligase Ligand-Linker Conjugates 7|||VH032-PEG4-NH2
(S, R, S)-AHPC-PEG4-NH2 hydrochloride is a chemically synthesized conjugate consisting of an E3 ligase ligand-linker, incorporating the VHL ligand based on (S, R, S)-AHPC, and a 4-unit PEG linker, which are specifically designed for use in PROTAC technology.
价 格：￥电议型 号：T15190产 地：中国大陆
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T15189Thalidomide-O-amido-C4-N3；化合物Thalidomide-O-amido-C4-N3E3 ligase Ligand-Linker Conjugates 18|||Cerebl
Thalidomide-O-amido-C4-N3 (Cereblon Ligand-Linker Conjugates 4) is an E3 ligase ligand-linker conjugate incorporating the Thalidomide-based cereblon ligand and a linker.
价 格：￥电议型 号：T15189产 地：中国大陆
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T15096Delgocitinib；迪高替尼JTE-052|||Corectim（Delgocitinib）；JTE-052|||迪高替尼|||Corectim（Delgocitinib）
Delgocitinib (JTE-052) is a specific JAK (Janus kinase) inhibitor with IC50 values of 2.8, 2.6, 13, and 58 nM for JAK1, JAK2, JAK3, and Tyk2 respectively. Delgocitinib is involved in various inflammatory and autoimmune diseases through JAK-dependent cytokines, and can effectively suppress multiple cytokine signaling while inhibiting itching caused by cytokines. It is widely used to treat various inflammatory diseases, including autoimmune diseases and hypersensitivity reactions.
价 格：￥电议型 号：T15096产 地：中国大陆
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T14975CJ-42794；化合物CJ-42794CJ-042794；CJ-042794
CJ-42794 (CJ-042794) is a selective antagonist of prostaglandin E receptor subtype 4 (EP4). It inhibits [3H]-PGE2 binding to the human EP4 receptor (a mean pKi: 8.5). CJ-42794 is a binding affinity that was at least 200-fold more selective for the human EP4 receptor than other human EP receptor subtypes (EP1, EP2, and EP3) (IC50 : 8.5 (pKi )).
价 格：￥电议型 号：T14975产 地：中国大陆
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T14547JWG-071；化合物JWG-071JWG071|||JWG 071；JWG071|||JWG 071
JWG-071, the first reported chemical probe for ERK5 kinase selectivity, is a BET-selective inhibitor with a 1 μM BRD4 IC that enhances both ERK5 activity and BRD4 selectivity.
价 格：￥电议型 号：T14547产 地：中国大陆
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T14546Bermoprofen；柏莫洛芬AD-1590|||AJ-1590；AD-1590|||AJ-1590
Bermoprofen (AD-1590) is an orally active non-steroidal anti-inflammatory compound with anti-inflammatory and analgesic activity used in the study of gastric ulcers.
价 格：￥电议型 号：T14546产 地：中国大陆
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T14338Atabecestat；化合物 T14338JNJ-54861911；JNJ-54861911
Atabecestat (JNJ-54861911) is a potent brain-penetrant and orally active β-site amyloid precursor protein cleaving enzyme 1 (BACE1) inhibitor, achieves robust and high CSF Aβ reduction and it is tolerated and displays a sustained pharmacokinetic (PK) and pharmacodynamic (PD) characteristics. Atabecestat (JNJ-54861911) has the potential for Alzheimer´s Disease treatment[1].
价 格：￥电议型 号：T14338产 地：中国大陆
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T14332Asoprisnil；化合物 T14332J867；J867
Asoprisnil is a selective modulator of progesterone receptor.
价 格：￥电议型 号：T14332产 地：中国大陆
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T1415Gemfibrozil；吉非罗齐CI-719|||Jezil|||Decrelip|||Lopid；吉非罗齐|||CI-719|||Jezil|||Decrelip|||Lopid
Gemfibrozil (CI-719) interacts with peroxisome proliferator-activated receptors (PPARalpha) resulting in PPARalpha-mediated stimulation of fatty acid oxidation and an increase in lipoprotein lipase (LPL) synthesis. Gemfibrozil is a fibric acid derivative with hypolipidemic effects. This enhances triglyceride-rich lipoprotein clearance and reduces the expression of apolipoprotein C-III (apoC-III). The reduction in hepatic production of apoC-III result in the subsequent reduction of serum levels o
价 格：￥电议型 号：T1415产 地：中国大陆
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T13970Xinjiachalcone A；化合物 T13970Xinjiachalcone A
Xinjiachalcone A is a natural product isolated from Glycyrrhiza inflata Batalin. Xinjiachalcone A shows both a low MIC and a strong bactericidal activity against H. pylori(MIC : 12.5 to 50 μM, seventeen H. pylori strains).
价 格：￥电议型 号：T13970产 地：中国大陆
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T13902SSF-109；化合物 T13902Huanjunzuo；Huanjunzuo
SSF-109 is a broad-spectrum fungicide, has protective activity against plant disease.
价 格：￥电议型 号：T13902产 地：中国大陆
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T13887SJF620；化合物 T13887SJF620
SJF620 is a potent degrader of PROTAC BTK(DC50 : 7.9 nM).
价 格：￥电议型 号：T13887产 地：中国大陆
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T13861Rebaudioside J；瑞鲍迪甙 JRebaudioside J
Rebaudioside J is a Stevia rebaudiana constituent .
价 格：￥电议型 号：T13861产 地：中国大陆
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T13743JH-XI-10-02；化合物 T13743JH-XI-10-02
JH-XI-10-02 causes proteasomal degradation, does not affect CDK8 mRNA levels. JH-XI-10-02 shows no effect on CDK19. JH-XI-10-02 is a potent and selective degrader of CDK8, with an IC50 of 159 nM, based on PROTAC.
价 格：￥电议型 号：T13743产 地：中国大陆
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T13727Huangjiangsu A；化合物 T13727Huangjiangsu A
Huangjiangsu A has hepatoprotective potential against H2O2-induced cytotoxicity and ROS generation and could be promising as potential therapeutic agents for liver diseases. Huangjiangsu A is isolated from D. villosa.
价 格：￥电议型 号：T13727产 地：中国大陆
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T13699Gardenoin J；化合物 T13699Gardenoin J
Gardenoin J, a cycloartane triterpene derived from the exudate of Gardenia thailandica, is isolated.
价 格：￥电议型 号：T13699产 地：中国大陆
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T13571JAK-IN-10；化合物JAK-IN-10JAK-IN-10
JAK-IN-10 is a JAK inhibitor. JAK-IN-10 can be used for the research of dry eye disorders.
价 格：￥电议型 号：T13571产 地：中国大陆
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T13399Zinterol；净特罗MJ 9184；净特罗|||MJ 9184
Zinterol is a potent and selective agonist of β2-adrenoceptor. Zinterol increases ICa in a concentration-dependent manner(EC50 of 2.2 nM).
价 格：￥电议型 号：T13399产 地：中国大陆
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T13185Topiramate D12；化合物 T13185RWJ 17021 D12|||McN 4853 D12；RWJ 17021 D12|||McN 4853 D12
Topiramate D12 is a deuterium labeled Topiramate. Topiramate is an agent of broad-spectrum antiepileptic. Topiramate is an antagonist of GluR5 receptor.
价 格：￥电议型 号：T13185产 地：中国大陆
