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T19219c-Kit-IN-3 D-tartrate；化合物 T19219c-Kit-IN-3 D-tartrate
c-Kit-IN-3 D-tartrate is a potent and selective c-KIT kinase inhibitor (IC50s: 4 nM, 8 nM for c-KIT wt, and c-KIT T670I).
价 格：￥电议型 号：T19219产 地：中国大陆
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T1920Capivasertib；化合物CapivasertibAZD5363；AZD5363
Capivasertib (AZD5363) is a broad-spectrum AKT inhibitor with inhibitory activity against Akt1, Akt2, and Akt3 (IC50=3/7/7 nM) with oral activity. Capivasertib has antitumor activity for the treatment of breast cancer.
价 格：￥电议型 号：T1920产 地：中国大陆
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T19182Afegostat D-Tartrate；化合物 T19182Isofagomine D-Tartrate|||D-Isofagomine D-Tartrate；Isofagomine D-Tartr
Afegostat D-Tartrate is a pharmacological chaperone that specifically and reversibly binds acid-β-glucosidase (GCase) in the endoplasmic reticulum with high affinity.
价 格：￥电议型 号：T19182产 地：中国大陆
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T1911Afuresertib；化合物AfuresertibGSK2110183C|||GSK2110183；GSK2110183C|||GSK2110183
Afuresertib (GSK2110183) is an orally bioavailable inhibitor of the serine/threonine protein kinase Akt (protein kinase B) with potential antineoplastic activity.
价 格：￥电议型 号：T1911产 地：中国大陆
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T19056Safflower yellow；红花黄Saffron powder|||Carthamas yellow；Saffron powder|||Carthamas yellow|||红花黄
Safflower yellow (Saffron powder) is extracted from the flowers of the plant safflower (Carthamus tinctorius). As traditional Chinese medicine, safflower has been extensively used for the treatment of cardio-cerebrovascular diseases.
价 格：￥电议型 号：T19056产 地：中国大陆
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T19055RT-NH2；化合物 T19055Real Thiol-NH2；Real Thiol-NH2
RT-NH2 is fairly hydrophobic and cannot distribute in the nucleus. It is a RealThiol prototype without the carboxylic acid groups.
价 格：￥电议型 号：T19055产 地：中国大陆
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T18794Tetrazine-Ph-NHCO-C3-NHS ester；化合物Tetrazine-Ph-NHCO-C3-NHS esterTetrazine-Ph-NHCO-C3-NHS ester
Tetrazine-Ph-NHCO-C3-NHS ester is a PEG-derived linker for PROTACs synthesis.
价 格：￥电议型 号：T18794产 地：中国大陆
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T18788tert-Butyl 11-aminoundecanoate；化合物tert-Butyl 11-aminoundecanoatetert-Butyl 11-aminoundecanoate
tert-Butyl 11-aminoundecanoate is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
价 格：￥电议型 号：T18788产 地：中国大陆
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T18656S-acetyl-PEG2-Boc化合物S-acetyl-PEG2-BocTert-Butyl 3-[2-(2-Acetylsulfanylethoxy)Ethoxy]Propanoate|||S-A
S-acetyl-PEG2-Boc (S-Acetyl-PEG2-T-Butyl Ester) is a PEG-based PROTAC linker. S-acetyl-PEG2-Boc can be used in the synthesis of PROTACs.
价 格：￥电议型 号：T18656产 地：中国大陆
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T18652RTC-30；化合物 T18652RTC-30
RTC-30 is an optimized phenothiazine compound possessing potent anti-cancer properties. It is formulated with a hydroxylated linker (N) which enhances its oral bioavailability[1].
价 格：￥电议型 号：T18652产 地：中国大陆
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T18641SirReal1-O-propargyl；化合物 T18641PROTAC Sirt2-binding moiety 1；PROTAC Sirt2-binding moiety 1
SirReal1-O-propargyl, a moiety based on SirReal1, is a selective and highly potent inhibitor of Sirtuin 2 (Sirt2), demonstrating an IC50 of 2.4 μM. It operates by binding to the cereblon ligand through a linker, facilitating the formation of PROTAC for the degradation of Sirt2[1].
价 格：￥电议型 号：T18641产 地：中国大陆
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T18540Phe-Lys(Trt)-PAB；化合物Phe-Lys(Trt)-PABPhe-Lys(Trt)-PAB
Phe-Lys(Trt)-PAB is a cathepsin-cleavable linker utilized in the development of antibody-drug conjugates (ADCs)[1], serving as a crucial component for facilitating the release of therapeutic agents within targeted cells.
价 格：￥电议型 号：T18540产 地：中国大陆
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T1838Sapanisertib；沙帕色替TAK-228|||MLN0128|||INK 128；沙帕色替|||TAK-228|||MLN0128|||INK 128
Sapanisertib (INK 128) is an orally bioavailable inhibitor of raptor-mTOR (TOR complex 1 or TORC1) and rictor-mTOR (TOR complex 2 or TORC2) with potential antineoplastic activity.
价 格：￥电议型 号：T1838产 地：中国大陆
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T18053Ipatasertib-NH2；化合物 T18053RG7440-NH2|||GDC-0068-NH2；RG7440-NH2|||GDC-0068-NH2
Ipatasertib-NH2 (GDC-0068-NH2;RG7440-NH2) is a ligand for target protein AKT for PROTAC, binds to lenalidomide, a ligand of ubiquitin E3 ligase cereblon (CRBN), via a ten-hydrocarbon linker to form INY-03-041 to degrade AKT[1].
价 格：￥电议型 号：T18053产 地：中国大陆
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T17980Fmoc-Phe-Lys(Trt)-PAB-PNP；化合物 T17980Fmoc Phe Lys(Trt) PAB PNP|||Fmoc-Phe-Lys(Trt)-PAB-PNP|||FmocPheL
Fmoc-Phe-Lys(Trt)-PAB-PNP is a cleavable linker for antibody-drug conjugate (ADC) synthesis, specifically designed for use in ADC synthesis.
价 格：￥电议型 号：T17980产 地：中国大陆
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T17946Fmoc-Ala-Ala-Asn(Trt)-OH；化合物Fmoc-Ala-Ala-Asn(Trt)-OHFmoc-Ala-Ala-Asn(Trt)-OH
Fmoc-Ala-Ala-Asn(Trt)-OH is a cleavable linker vital in ADC synthesis. Fmoc-Ala-Ala-Asn(Trt)-OH joins cytotoxic drugs to antibodies, enabling precise delivery to cells or proteins. The cleavable nature ensures controlled drug release, optimizing ADC effectiveness.
价 格：￥电议型 号：T17946产 地：中国大陆
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T1780Parecoxib；帕瑞昔布SC 69124|||Vorth-P|||Valus-P；SC 69124|||帕瑞昔布|||Vorth-P|||Valus-P
Parecoxib (SC 69124) is an effective and selective COX-2 inhibitor.
价 格：￥电议型 号：T1780产 地：中国大陆
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T1748Kartogenin；化合物KartogeninKGN；KGN
Kartogenin (KGN) is an activator of the smad4/smad5 pathway, and promotes the selective differentiation of multipotent mesenchymal stem cells into chondrocytes.
价 格：￥电议型 号：T1748产 地：中国大陆
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T17184Tyrosine kinase inhibitor；化合物Tyrosine kinase inhibitorTyrosine kinase inhibitor
Tyrosine kinase inhibitor is a tyrosine kinase inhibitor used in combination with fragmenting aromatic nitrogen compounds as antiproliferative agents.
价 格：￥电议型 号：T17184产 地：中国大陆
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T17165Tris[[2-(tert-butoxycarbonyl)ethoxy]methyl]methylamine化合物 T17165tris-2-tert-butoxycarbonyl-ethoxy-me
Tris[[2-(tert-butoxycarbonyl)ethoxy]methyl]methylamine, a cleavable PEG ADC linker, is employed in the synthesis of antibody-drug conjugates (ADCs). It is also a PEG-based PROTAC linker, specifically Amino-Tri-(t-butoxycarbonylethoxymethyl)-methane, widely used in the synthesis of PROTACs[1].
价 格：￥电议型 号：T17165产 地：中国大陆
