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T11485GSK2643943A;化合物GSK2643943AGSK2643943A
GSK2643943A is a deubiquitylating enzyme (DUB) inhibitor, with an IC 50 of 160 nM for USP20/Ub-Rho. GSK2643943A has anti-tumor efficacy.
价 格:¥电议型 号:T11485产 地:中国大陆
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T11483GSK256066 Trifluoroacetate化合物 T11483GSK 256066 Trifluoroacetate|||GSK256066 (2,2,2-trifluoroacetic a
GSK 256066 Trifluoroacetate is a selective and high-affinity phosphodiesterase 4 (PDE) inhibitor (IC50: 3.2 pM for PDE4B). It can be used for the treatment of chronic obstructive pulmonary disease.
价 格:¥电议型 号:T11483产 地:中国大陆
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T11481GSK2239633A;化合物GSK2239633AGSK2239633A
GSK2239633A is an allosteric antagonist of CC-chemokine receptor 4 (CCR4) with a pIC50 of 7.96 for the binding of [125I]-TARC to human CCR4.
价 格:¥电议型 号:T11481产 地:中国大陆
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T11479GSK1521498;化合物 T11479GSK1521498
GSK1521498 is a selective antagonist of the μ-opioid receptor (MOR). It is being used for the treatment of disorders of compulsive consumption of food, alcohol, and drugs.
价 格:¥电议型 号:T11479产 地:中国大陆
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T11478LGSK1521498 free base;化合物 T11478LGSK1521498 free base
GSK1521498 free base is a potent and selective antagonist of the μ-opioid receptor. GSK1521498 free base also has the potential for disorders of compulsive consumption of food, alcohol, and drugs.
价 格:¥电议型 号:T11478L产 地:中国大陆
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T11472LMolibresib besylate化合物 T11472LI-BET 762 besylate|||GSK 525762C
Molibresib besylate is an inhibitor of BET bromodomain (IC50: 32.5-42.5 nM).
价 格:¥电议型 号:T11472L产 地:中国大陆
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T11472GSK 525768A;化合物 T11472GSK 525768A
GSK 525768A, the inactive enantiomer of GSK525762A, exhibits no activity towards BET.
价 格:¥电议型 号:T11472产 地:中国大陆
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T11469GSK-3484862;化合物GSK-3484862GSK-3484862
Gsk-3484862 is a non covalent inhibitor of DNA methyltransferase DNMT1 with anticancer activity. Gsk-3484862 mediates the global demethylation of mouse embryonic stem cells.
价 格:¥电议型 号:T11469产 地:中国大陆
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T11459GPR40 agonist 1;化合物 T11459GPR40 agonist 1
GPR40 agonist 1 is an effective new GPR40 agonist (EC50s: 17 nM and 2 nM for rGPR40 and hGPR40).
价 格:¥电议型 号:T11459产 地:中国大陆
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T1144LLidocaine Hydrochloride hydrate;盐酸利多卡因一水合物Lidocaine Hydrochloride hydrate
Lidocaine Hydrochloride hydrate is an amide local anesthetic, has anti-inflammatory property.
价 格:¥电议型 号:T1144L产 地:中国大陆
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T11449LGolotimod;戈洛莫德Gamma-D-glutamyl-L-tryptophan|||SCV 07;Gamma-D-glutamyl-L-tryptophan|||SCV 07
Golotimod (SCV 07) is an antimicrobial dipeptide with immunomodulatory activity that significantly improves the efficacy of anti-tuberculosis therapy, induces thymic and splenic cell proliferation, modulates macrophage function, and inhibits STAT3 signaling.Golotimod has been used in the study of recurrent genital Herpes Simplex Virus 2 (HSV-2) infection and oral mucositis.
价 格:¥电议型 号:T11449L产 地:中国大陆
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T11449Golotimod hydrochloride (229305-39-9 free base);化合物 T11449Golotimod hydrochloride|||Gamma-D-glutamyl
Golotimod hydrochloride (SCV 07 hydrochloride) is an immunomodulating peptide with antimicrobial properties. It enhances antituberculosis therapy effectiveness, promotes thymic and splenic cell proliferation, and boosts macrophage functionality. Furthermore, it inhibits STAT3 signaling, thereby modifying the duration and intensity of oral mucositis in animal models subjected to radiation or a combination of radiation and Cisplatin. Additionally, Golotimod hydrochloride has shown potential as a t
价 格:¥电议型 号:T11449产 地:中国大陆
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T11439GNE-616;化合物 T11439GNE-616
GNE-616 is a highly potent, metabolically stable, orally bioavailable, and subtype-selective Nav1.7 inhibitor (Ki: 0.79 nM, Kd: 0.38 nM for hNav1.7) for the treatment of chronic pain.
价 格:¥电议型 号:T11439产 地:中国大陆
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T11437GNE-0439;化合物 T11437GNE-0439
GNE-0439 is a novel Nav1.7-selective inhibitor (IC50: 0.34 uM) and inhibits Nav1.5 (IC50: 38.3 μM). GNE-0439 inhibits mutant N1742K channels (IC50: 0.37 uM) in membrane potential assays.
价 格:¥电议型 号:T11437产 地:中国大陆
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T11429Glycolic acid oxidase inhibitor 1;化合物 T11429Glycolic acid oxidase inhibitor 1
Glycolic acid oxidase inhibitor 1 is a glycolate oxidase inhibitor.
价 格:¥电议型 号:T11429产 地:中国大陆
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T11419O6BTG-octylglucoside化合物 T11419Glucose-conjugated MGMT inhibitor
O6BTG-octylglucoside is a potent O6-methylguanine-DNAmethyl-transferase (MGMT) inhibitor (IC50s: 10 nM and 32 nM in HeLa S3 cells and in vitro (cell extracts)).
价 格:¥电议型 号:T11419产 地:中国大陆
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T11410LGLPG0492;化合物GLPG0492GLPG0492
GLPG0492 is a novel selective androgen receptor modulator. After oral dosing, it showed anabolic activity on muscle, strongly dissociated from the androgenic activity on the prostate.
价 格:¥电议型 号:T11410L产 地:中国大陆
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T11409GLP-26;化合物GLP-26GLP-26
GLP-26, an HBV capsid assembly regulator (CAM), inhibits HBV DNA replication (IC50=3 nM) in the Hep AD38 system and reduces cccDNA by >90% at 1 μM. GLP-26 disrupts the encapsidation of pregenomic RNA, leading to nucleocapsid disassembly and reducing the cccDNA library.
价 格:¥电议型 号:T11409产 地:中国大陆
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T11403LGln-AMS TFA (209543-57-7 free base);化合物 T11403LGln-AMS TFA;Gln-AMS TFA
Gln-AMS(TFA) inhibits glutaminyl-tRNA synthetase (GlnRS) with a Ki of 1.32 μM. Gln-AMS (TFA) is a type Ia aminoacyl-tRNA synthetase (AARS) inhibitor.
价 格:¥电议型 号:T11403L产 地:中国大陆
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T11402LGKI-1 HCl;GKI-1盐酸盐GKI-1 HCl( 2444764-03-6 Free base);GKI-1 HCl( 2444764-03-6 Free base)
GKI-1 HCl is a Greatwall (GWL) kinase inhibitor that inhibits hGWLFL and hGWL-KinDom.The inhibitory effect of GKI-1 HCl on ROCK1 is more significant.
价 格:¥电议型 号:T11402L产 地:中国大陆