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T11186EMPA;化合物EMPAEMPA
EMPA is a selective, high-affinity and reversible antagonist of orexin OX2 receptor(human and rat OX2-HEK293 membranes with KD values of 1.1 and 1.4 nM respectively)
价 格:¥电议型 号:T11186产 地:中国大陆
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T11179Elubrixin;化合物ElubrixinSB-656933;SB-656933
Elubrixin (SB-656933) inhibits neutrophil CD11b upregulation (IC50 of 260.7 nM) and shape change (IC50 of 310.5 nM). Elubrixin can be used for inflammatory diseases such as inflammatory bowel disease and airway inflammation. Elubrixin is a potent, selective, competitive, reversible and orally active CXCR2 antagonist and an IL-8 receptor antagonist.
价 格:¥电议型 号:T11179产 地:中国大陆
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T11178LELN318463 racemate;化合物ELN318463 racemateELN318463 (racemate)|||ELN 318463 racemate;ELN318463 (racema
ELN318463 racemate (ELN 318463 racemate) is the racemate of ELN318463 which is an amyloid precursor protein (APP) selective γ-secretase inhibitor.
价 格:¥电议型 号:T11178L产 地:中国大陆
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T11177Elinogrel;化合物ElinogrelPRT060128;PRT060128
Elinogrel (PRT060128) is a competitive and reversible antagonist of platelet P2Y12 with IC50 of 20 nM and exhibits potent antiplatelet effects.
价 格:¥电议型 号:T11177产 地:中国大陆
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T11176Eliglustat hemitartrate;依利格鲁司特酒石酸盐Genz-112638|||Eliglustat tartrate;Genz-112638|||依利格鲁司特酒石酸盐|||Eligl
Eliglustat hemitartrate (Genz-112638) , with an IC50 of 24 nM, is a specific, potent, oral active glucocerebral glycosidase inhibitor.
价 格:¥电议型 号:T11176产 地:中国大陆
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T11175Elenbecestat;化合物ElenbecestatE2609;E2609
Elenbecestat (E2609) is an effective oral bioutilization and CNS penetrating ACE-1 inhibitor for the treatment of Alzheimer´s disease.
价 格:¥电议型 号:T11175产 地:中国大陆
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T11173LElacestrant S enantiomer dihydrochloride;化合物 T11173LRAD1901 S enantiomer dihydrochloride|||RAD-1901
Elacestrant (RAD1901) dihydrochloride is a selective and orally available estrogen receptor (ERR) degrader with IC50 values of 48 and 870 nM for ERα and ERβ, respectively. Elacestrant S enantiomer dihydrochloride is an low activity enantiomer of elacestrant dihydrochloride.
价 格:¥电议型 号:T11173L产 地:中国大陆
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T11169Eicosatetraynoic acid;化合物 T11169ETYA;ETYA
Eicosatetraynoic acid (ETYA) activates PPARα and PPARγ chimeras at 10 μM. Eicosatetraynoic acid (ETYA) is a nonspecific inhibitor of cyclooxygenase and lipoxygenase (ID50=8 μM and 4 μM, respectively).
价 格:¥电议型 号:T11169产 地:中国大陆
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T11163EGFR-IN-9;化合物EGFR-IN-9EGFR-IN-9
EGFR-IN-9 is a potent EGFR kinase inhibitor with IC50s of 7 nM, 28 nM for the wild type EGFR kinase and double mutant EGFR kinase (L858R/T790M). EGFR-IN-9 has antitumor activity.
价 格:¥电议型 号:T11163产 地:中国大陆
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T11159EGFR-IN-2;化合物 T11159EGFR-IN-2
EGFR-IN-2 is a non-covalent, mutation-selective and irreversible second-generation EGFR inhibitor.
价 格:¥电议型 号:T11159产 地:中国大陆
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T11157LEGFR-IN-1 hydrochloride;EGFR-IN-1盐酸盐EGFR-IN-1 hydrochloride
EGFR-IN-1 hydrochloride is an irreversible and specific inhibitor of L858R/T790M mutant EGFR with 100-fold selectivity over wild-type EGFR. EGFR-IN-1 hydrochloride exhibits potent antitumor and antiproliferative activity in H1975 cells and the mutant HCC827 cells with IC50s of 4 and 28 nM, respectively.
价 格:¥电议型 号:T11157L产 地:中国大陆
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T11156LNazartinib mesylate;化合物 T11156LEGF816 (mesylate);EGF816 (mesylate)
Nazartinib mesylate is a novel, covalent mutant-selective inhibitor of EGFR (Ki and Kinact: 31 nM and 0.222/min on EGFR(L858R/790M) mutant).
价 格:¥电议型 号:T11156L产 地:中国大陆
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T11154LEG01377 2HCl;EG01377二盐酸盐EG01377 2HCl(2227996-00-9 Free base);EG01377 2HCl(2227996-00-9 Free base)
EG01377 2HCl is a potent, bioavailable and selective inhibitor of neuropilin-1 (NRP1) with a Kd value of 1.32 μM and an IC50 value of 609 nM for both EG01377 2HCl against NRP1-a1 and NRP1-b1.EG01377 exhibits anti-angiogenic, antimigratory and antitumor activities.
价 格:¥电议型 号:T11154L产 地:中国大陆
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T11153EG00229;化合物 T11153EG00229
EG00229 is a neuropilin 1 (NRP1) receptor antagonist that selectively inhibits the binding of VEGF-A to the NRP1 b1 domain, achieving this inhibition with an IC50 value of 3 μM. It does not affect the binding of VEGF-A to other receptors, such as VEGFR-1 and VEGFR-2.
价 格:¥电议型 号:T11153产 地:中国大陆
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T11149Ecopladib;化合物EcopladibPLA 725;PLA 725
Ecopladib (PLA 725) is a sub-micromolar inhibitor of cytosolic phospholipase A2α (cPLA2α), with IC50s of 0.15 μM and 0.11 μM in the GLU micelle and rat whole blood assays, respectively.
价 格:¥电议型 号:T11149产 地:中国大陆
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T11148Ecastolol;依卡洛尔Ecastolol
Ecastolol has anti-angina activity and is an adrenergic receptor antagonist.
价 格:¥电议型 号:T11148产 地:中国大陆
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T11146EC359;化合物EC359EC-359;EC-359
EC359 is a potent and selective inhibitor of leukemia inhibitory factor receptor (LIFR), a potent inhibitor with anticancer activity, blocks LIF/LIFR interaction, and can be used in the study of leukemia and endometrial cancer.
价 格:¥电议型 号:T11146产 地:中国大陆
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T11139(E/Z)-BCI;化合物(E/Z)-BCINSC 150117;NSC 150117
(E/Z)-BCI (NSC-150117), a dual-specificity phosphatase 6 (DUSP6) inhibitor with anti-inflammatory properties, reduces LPS-induced inflammatory mediators and ROS production in macrophage cells by activating the Nrf2 signaling axis and inhibiting the NF-κB pathway.
价 格:¥电议型 号:T11139产 地:中国大陆
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T11138LLHF-535;化合物LHF-535LHF-535
LHF-535 is an antiviral compound. It has EC50s of <1 μM, <1 μM, <1 μM, and 1-10 μM for Lassa, Machupo, Junin, and VSVg virus, respectively.
价 格:¥电议型 号:T11138L产 地:中国大陆
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T11129LDuvelisib (R enantiomer) hydrochloride;杜韦利西布R对映体盐酸盐IPI-145 R enantiomer HCl|||Duvelisib (R enantiome
Duvelisib (R enantiomer) hydrochloride (INK1197 R enantiomer HCl) is a PI3K inhibitor. Duvelisib (R enantiomer) hydrochloride is the less active enantiomer of Duvelisib.
价 格:¥电议型 号:T11129L产 地:中国大陆