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T11059DM4-SMe;化合物 T11059DM4-SMe
DM4-SMe is a cytotoxic part of antibody-drug conjugates (ADCs) and a metabolite of antibody-maytansin conjugates (AMCs) and tubulin inhibitors, which can also be stabilized by disulfide bonds or thioether The bond binds to the antibody. The IC50 of DM4-SMe on KB cells was 0.026 nM.
价 格:¥电议型 号:T11059产 地:中国大陆
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T11055DL-TBOA化合物 T11055DL TBOA|||DLTBOA
DL-TBOA inhibited [14C] glutamate uptake in COS-1 cells expressing human EAAT1 and EAAT2, with Ki values of 42 μM and 5.7 μM, respectively. DL-TBOA blocks EAAT4 and EAAT5 in a competitive manner, with Ki values of 4.4 μM and 3.2 μM, respectively. DL-TBOA is an effective non-transportable excitatory amino acid transporter inhibitor with IC50 of 70 μM, 6 μM and 6 μM for excitatory amino acid transporter 1 (EAAT1, EAAT2 and EAAT3), respectively.
价 格:¥电议型 号:T11055产 地:中国大陆
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T11052LDisitertide acetate;地司特泰醋酸盐P144 acetate|||Disitertide acetate(272105-42-7 Free base);P144 acetate|||
Disitertide acetate (P144 acetate) is a peptidic transforming growth factor-beta 1 (TGF-β1) inhibitor specifically designed to block the interaction with its receptor. Disitertide acetate is also a PI3K inhibitor and an apoptosis inducer.
价 格:¥电议型 号:T11052L产 地:中国大陆
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T11050Dipyrocetyl;地匹乙酯Dipyrocetyl
Dipyrocetyl has anti-inflammatory and analgesic effects.
价 格:¥电议型 号:T11050产 地:中国大陆
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T11049Diprotin A TFA化合物 T11049Ile-Pro-Pro (TFA)
Diprotin A (TFA) is an inhibitor of dipeptidyl peptidase IV (DPP-IV).
价 格:¥电议型 号:T11049产 地:中国大陆
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T11048LDIPQUO hydrochloride;化合物DIPQUO盐酸盐DIPQUO hydrochloride(1269365-82-3 Free base);DIPQUO hydrochloride(1
DIPQUO hydrochloride is an activator of the bone marker alkaline phosphatase (ALP), with an EC50 of 6.27 μM in C2C12 cells. DIPQUO hydrochloride promotes mouse and human osteoblast differentiation via activation of p38 MAPK-β.
价 格:¥电议型 号:T11048L产 地:中国大陆
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T11039Didesethyl chloroquine;二去乙基氯喹Bisdesethylchloroquine;Bisdesethylchloroquine
Didesethyl chloroquine (Bisdesethylchloroquine) is an effective myocardial inhibitor. Didesethyl chloroquine (Bisdesethylchloroquine) is the main metabolite of the antimalarial drug chloroquine.
价 格:¥电议型 号:T11039产 地:中国大陆
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T11031hDHODH-IN-7;化合物hDHODH-IN-7DHODH-IN-9;DHODH-IN-9
hDHODH-IN-7 (DHODH-IN-9) is a nitrogen-containing analog and is a human dihydrorotatory dehydrogenase inhibitor. hDHODH-IN-7 and pMIC50 of 7.4 have antiviral effects.
价 格:¥电议型 号:T11031产 地:中国大陆
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T11029hDHODH-IN-5;化合物hDHODH-IN-5DHODH-IN-7;DHODH-IN-7
hDHODH-IN-5 is an inhibitor of human dihydroorotate dehydrogenase (hDHODH, IC50 = 0.91 μM).
价 格:¥电议型 号:T11029产 地:中国大陆
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T11019DHODH-IN-1;化合物DHODH-IN-1DHODH-IN-1
DHODH-IN-1 is a potent dihydroorotate dehydrogenase (DHODH) inhibitor with IC50 of 25 nM. DHODH-IN-1 is an inhibitor of the pyrimidine biosynthetic pathway.
价 格:¥电议型 号:T11019产 地:中国大陆
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T11013L2Levorotation nimorazole phosphate ester TFA;左旋尼莫唑磷酸酯TFALevorotation nimorazole phosphate ester TFA
Levorotation nimorazole phosphate ester TFA is an anti-anaerobic and anti-parasitic agent.
价 格:¥电议型 号:T11013L2产 地:中国大陆
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T11013L1Dextrorotation nimorazole phosphate ester TFA;右旋尼莫唑磷酸酯TFADextrorotation nimorazole phosphate ester T
Dextrorotation nimorazole phosphate ester TFA is an anti-anaerobic and anti-parasitic agent.
价 格:¥电议型 号:T11013L1产 地:中国大陆
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T11009Destruxin B;黑僵菌素 BDestruxin B
Destruxin B is a cyclic peptide with insecticidal and anticancer activity isolated from the insect pathogenic fungus Metarhizium isopliae. Destruxin B induces apoptosis of human non-small cell lung cancer cells through the Bcl-2 family-dependent mitochondrial pathway. Destruxin B through caspase-mediated apoptosis can significantly activate caspase-3 in vitro and in vivo, reducing the proliferation of tumor cells.
价 格:¥电议型 号:T11009产 地:中国大陆
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T11007LLevofloxacin Hydrochloride Impurity A;左氧氟沙星杂质A(盐酸盐)Levofloxacin Hydrochloride Impurity A(117707-40-1
Levofloxacin Hydrochloride Impurity A I, one of the quinolones, has a broad spectrum of antibacterial action.
价 格:¥电议型 号:T11007L产 地:中国大陆
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T11001LDesethyl chloroquine diphosphate;化合物 T11001LDesethyl chloroquine diphosphate
Desethyl chloroquine diphosphate is the main deethyl metabolite of chloroquine. Chloroquine diphosphate is an inhibitor of autophagy and toll-like receptors (TLRs). Chloroquine diphosphate has anti-plasma activity.
价 格:¥电议型 号:T11001L产 地:中国大陆
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T10999Desbutyl Lumefantrine;化合物 T10999Desbutyl-benflumetol;Desbutyl-benflumetol
Desbutyl Lumefantrine is a metabolite of lumefantrine with antimalarial activity.
价 格:¥电议型 号:T10999产 地:中国大陆
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T10994LDeltasonamide 2 hydrochloride;化合物 T10994LDeltasonamide 2 hydrochloride (2088485-34-9 free base);Delt
Deltasonamide 2 hydrochloride is a competitive high-affinity PDEδ inhibitor with a Kd of approximately 385 pM.
价 格:¥电议型 号:T10994L产 地:中国大陆
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T10989Dehydroaripiprazole;化合物DehydroaripiprazoleOPC-14857|||DM-14857;OPC-14857|||DM-14857
Dehydroaripiprazole (DM-14857) is the active metabolite of aripiprazole. Aripiprazole is an antipsychotic drug, which is metabolized by CYP3A4 and CYP2D6 and mainly forms dehydroaripiprazole. Dehydroaripiprazole has antipsychotic activity equivalent to aripiprazole.
价 格:¥电议型 号:T10989产 地:中国大陆
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T10988LDegarelix acetate(214766-78-6 free base);化合物Degarelix acetateDegarelix acetate(214766-78-6 free base
Degarelix acetate is a competitive and reversible antagonist of gonadotropin-releasing hormone receptor (GnRHR) .
价 格:¥电议型 号:T10988L产 地:中国大陆
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T10983LDDP-38003 dihydrochloride;DDP-38003盐酸盐DDP-38003 dihydrochloride
DDP-38003 dihydrochloride is an orally available histone lysine-specific demethylase 1A (KDM1A/LSD1) inhibitor (IC50: 84 nM).
价 格:¥电议型 号:T10983L产 地:中国大陆