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T16573Pratosartan;化合物 T16573KT 3671|||FW 7203|||KD 3-671;KT 3671|||FW 7203|||KD 3-671
Pratosartan is a selective antagonist of angiotensin II receptor.
价 格:¥电议型 号:T16573产 地:中国大陆
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T1657Varenicline Tartrate;酒石酸伐尼克兰Champix tartrate|||Chantix tartrate|||CP 526555-18;Champix tartrate|||酒石
Varenicline Tartrate (CP 526555-18) is a benzazepine derivative that functions as an ALPHA4/BETA2 NICOTINIC RECEPTOR partial agonist. It is used for SMOKING CESSATION.
价 格:¥电议型 号:T1657产 地:中国大陆
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T16470Penthiopyrad;吡噻菌胺Vertisan|||MTF-753;Vertisan|||MTF-753
Penthiopyrad (MTF-753) shows a broad spectrum of antifungal activity and suppresses fungal respiration. Penthiopyrad can be used in studies about foliar and soil-borne plant diseases.
价 格:¥电议型 号:T16470产 地:中国大陆
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T1628Rivastigmine tartrate;酒石酸卡巴拉汀SDZ-ENA 713|||ENA 713;SDZ-ENA 713|||ENA 713|||酒石酸卡巴拉汀
Rivastigmine tartrate (SDZ-ENA 713) is a carbamate-derived reversible CHOLINESTERASE INHIBITOR that is selective for the CENTRAL NERVOUS SYSTEM and is used for the treatment of DEMENTIA in ALZHEIMER DISEASE and PARKINSON DISEASE.
价 格:¥电议型 号:T1628产 地:中国大陆
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T16162Mutated EGFR-IN-1;AZD9291中间体1Osimertinib analog;Osimertinib analog|||AZD9291中间体1
Mutated EGFR-IN-1 (Osimertinib analog) is a useful intermediate for the inhibitors design for mutated EGFR, such as L858R EGFR, Exonl9 deletion activating mutant, and T790M resistance mutant.
价 格:¥电议型 号:T16162产 地:中国大陆
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T1615LIrbesartan HCl;化合物 T1615LIrbesartan hydrochloride|||BMS186295|||BMS 186295|||BMS-186295;Irbesartan h
Irbesartan is an angiotensin II receptor antagonist used mainly for the treatment of hypertension. It selectively and competitively blocks the binding of angiotensin II to the angiotensin I receptor.
价 格:¥电议型 号:T1615L产 地:中国大陆
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T1615Irbesartan;厄贝沙坦SR-47436|||BMS-186295;厄贝沙坦|||SR-47436|||BMS-186295
Irbesartan (SR-47436) is an Angiotensin 2 Receptor Blocker. The mechanism of action of irbesartan is as an Angiotensin 2 Receptor Antagonist.
价 格:¥电议型 号:T1615产 地:中国大陆
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T16143MRTX-1257;化合物MRTX-1257MRTX-1257
MRTX-1257 is a selective, irreversible, and covalent inhibitor of KRAS G12C. It has an IC50 of 900 pM for KRAS dependent ERK phosphorylation in H358 cells. MRTX1257 demonstrated 31% bioavailability in the mouse, with free fraction exposures well above the cellular potency In a PK/PD experiment, 77% target engagement.
价 格:¥电议型 号:T16143产 地:中国大陆
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T16142MRT199665;化合物 T16142MRT199665
MRT199665 is an effective and ATP-competitive, selective MARK/SIK/AMPK inhibitor (IC50s of 2/2/3/2 nM, 10/10 nM, and 110/12/43 nM for MARK1/MARK2/MARK3/MARK14, AMPKα1/AMPKα2, and SIK1/SIK2/SIK3, respectively). MRT199665 suppresses the phosphorylation of SIK substrate CRTC3 at S370. MRT199665 induces apoptosis in MEF2C-activated human acute myeloid leukemia (AML) cells.
价 格:¥电议型 号:T16142产 地:中国大陆
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T16141MRT00033659;化合物 T16141MRT00033659
MRT00033659 is an effective broad-spectrum kinase inhibitor of CK1 (IC50=0.9 μM for CK1δ) and CHK1 (IC50=0.23 μM). MRT00033659 is a pyrazolo-pyridine analogue. It also induces p53 pathway activation and E2F-1 destabilization.
价 格:¥电议型 号:T16141产 地:中国大陆
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T16034Meclinertant;化合物 T16034SR 48692;SR 48692
Meclinertant is an effective, selective, nonpeptide, and orally active neurotensin receptor 1 (NTS1) antagonist. Meclinertant competitively antagonizes neurotensin-induced intracellular Ca2+ mobilization (pA2 : 8.13), in human colon carcinoma (HT-29) cells. Meclinertant has anxiolytic, anti-addictive, and memory-impairing effects.
价 格:¥电议型 号:T16034产 地:中国大陆
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T1596Chlormadinone acetate;醋酸氯地孕酮Gestafortin;Gestafortin|||醋酸氯地孕酮
Chlormadinone acetate (Gestafortin) is an orally active synthetic progestational hormone used often in combinations as an oral contraceptive.
价 格:¥电议型 号:T1596产 地:中国大陆
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T1570Telmisartan;替米沙坦BIBR 277;BIBR 277|||替米沙坦
Telmisartan (BIBR 277) is an Angiotensin 2 Receptor Blocker. The mechanism of action of telmisartan is as an Angiotensin 2 Receptor Antagonist.
价 格:¥电议型 号:T1570产 地:中国大陆
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T1558Resveratrol;白藜芦醇trans-Resveratrol|||SRT 501;白藜芦醇|||trans-Resveratrol|||SRT 501
Resveratrol (SRT 501) is a polyphenolic natural product, a plant antitoxin with antioxidant and chemopreventive activities. Resveratrol has a wide range of targets including COX, SIRT, LOC, etc. Resveratrol induces autophagy and apoptosis.
价 格:¥电议型 号:T1558产 地:中国大陆
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T15428Uprosertib hydrochloride;化合物 T15428GSK2141795 (hydrochloride);GSK2141795 (hydrochloride)
Uprosertib hydrochloride is a potent and selective inhibitor of pan-Akt (IC50: 180/328/38 nM for Akt1/Akt2/Akt3, respectively).
价 格:¥电议型 号:T15428产 地:中国大陆
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T15377Ravoxertinib hydrochloride化合物 T15377GDC-0994 (hydrochloride)
Ravoxertinib hydrochloride is an orally bioavailable and selective inhibitor for ERK kinase activity (IC50: 6.1 nM and 3.1 nM for ERK1 and ERK2, respectively).
价 格:¥电议型 号:T15377产 地:中国大陆
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T15329Fmoc-PEG3-Ala-Ala-Asn(Trt)-PAB;化合物 T15329Fmoc-PEG3-Ala-Ala-Asn(Trt)-PAB
Fmoc-PEG3-Ala-Ala-Asn(Trt)-PAB is a cleavable three-unit polyethylene glycol (PEG) linker employed in the synthesis of antibody-drug conjugates (ADCs)[1].
价 格:¥电议型 号:T15329产 地:中国大陆
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T15264Exicorilant;化合物 T15264CORT 125281;CORT 125281
Exicorilant is a selective and oral active glucocorticoid receptor (GR) antagonist (Ki: 7 nM) and it also has the potential to overcome adiposity, glucose intolerance, and dyslipidemia.
价 格:¥电议型 号:T15264产 地:中国大陆
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T15262Vactosertib Hydrochloride化合物 T15262TEW-7197 Hydrochloride|||EW-7197 Hydrochloride
Vactosertib Hydrochloride is an orally active and ATP-competitive ALK5 inhibitor (IC50: 12.9 nM). It has potently antimetastatic activity and anticancer effect. Vactosertib Hydrochloride also inhibits ALK2 and ALK4 (IC50: 17.3 nM).
价 格:¥电议型 号:T15262产 地:中国大陆
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T1525Ritonavir;利托那韦RTV|||Abbott 84538|||A 84538|||ABT 538;RTV|||利托那韦|||Abbott 84538|||A 84538|||ABT 538
Ritonavir (ABT 538) is a peptidomimetic agent that inhibits both HIV-1 and HIV-2 proteases. Ritonavir is highly inhibited by serum proteins but boosts the effect of other HIV proteases by blocking their degradation by cytochrome P450.
价 格:¥电议型 号:T1525产 地:中国大陆