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T4584BMS-813160;化合物BMS813160BMS 813160;BMS 813160
BMS-813160 is the first dual CCR2/CCR5 antagonist to enter Clinical development for cardiovascular.
价 格:¥电议型 号:T4584产 地:中国大陆
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T4583PFI-2 hydrochloride;化合物(R)-PFI-2 hydrochloride(R)-PFI-2 hydrochloride|||PFI-2 HCl;(R)-PFI-2 hydrochl
PFI-2 hydrochloride ((R)-PFI-2 hydrochloride) is a potent, highly selective, and cell-active inhibitor of the methyltransferase activity of SETD7 (IC50: 2 nM), 500 fold active than (S)-PFI-2.
价 格:¥电议型 号:T4583产 地:中国大陆
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T4582xanthanol;占吨氢醇NSC 4038;NSC 4038|||占吨氢醇
Xanthanol(NSC 4038) is used to test the levels of urea in the bloodstream.
价 格:¥电议型 号:T4582产 地:中国大陆
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T45804-Octyl itaconate4-辛基衣康酸4-辛基衣康酸|||衣康酸盐
4-Octyl Itaconate is a cell-permeable derivative of Itaconate, an anti-inflammatory metabolite. 4-Octyl Itaconate activates Nrf2 via alkylation of KEAP1 and also inhibits phosphorylation of STING. 4-Octyl Itaconate is an anti-inflammatory metabolite.
价 格:¥电议型 号:T4580产 地:中国大陆
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T4558Trioxsalen三甲沙林三甲沙林|||Trimethylpsoralen|||Trioxysalen|||Trisoralen
Trioxsalen (Trioxysalen) is a furanocoumarin and a psoralen derivative, in conjunction with UV-A for phototherapy treatment of vitiligo and hand eczema. After photoactivation it creates interstrand cross-links in DNA, which can cause programmed cell death.
价 格:¥电议型 号:T4558产 地:中国大陆
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T4258TLR7 agonist 2;化合物TLR7-agonist-1TLR7-agonist-1|||TLR7-IN-1;TLR7-agonist-1|||TLR7-IN-1
TLR7 agonist 2 (TLR7-IN-1) is a specific and effective Toll-like Receptor 7 (TLR7) agonist (LEC=0.4 μM).
价 格:¥电议型 号:T4258产 地:中国大陆
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T4230PF-3758309 hydrochloride;化合物PF-3758309 hydrochloridePF-03758309 hydrochloride;PF-03758309 hydrochlor
PF-3758309 hydrochloride (PF-03758309 hydrochloride) , is a PAK4 inhibitor, is also a n orally bioavailable small-molecule inhibitor of p21-activated kinase 4 (PAK4) with potential antineoplastic activity. PF-3758309 hydrochloride binds to PAK4, inhibiting PAK4 activity and cancer cell growth. PAK4, a serine/threonine kinase belonging to the p21-activated kinase (PAK) family, is often upregulated in a variety of cancer cell types and plays an important role in cancer cell motility, proliferation
价 格:¥电议型 号:T4230产 地:中国大陆
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T4199Desmethyl-VS-5584;化合物Desmethyl-VS-5584Desmethyl-VS-5584
Desmethyl-VS-5584 is a dimethyl analog of VS-5584, which is a novel and highly selective PI3K/mTOR kinase inhibitor for the treatment of cancer.
价 格:¥电议型 号:T4199产 地:中国大陆
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T413582-Hydroxybenzylamine;2-羟基苄胺2-Hydroxybenzylamine
2-Hydroxybenzylamine, a potent small molecule scavenger of IsoLGs, sequesters the reactive species as inert adducts. 2-Hydroxybenzylamine may be used to decrease early recurrence of atrial fibrillation and other atrial arrhythmias following atrial fibrillation ablation by decreasing IsoLG adducts with native biomolecules.
价 格:¥电议型 号:T41358产 地:中国大陆
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T41165ETP 45835 dihydrochloride;ETP 45835 dihydrochlorideETP 45835 dihydrochloride
ETP 45835 dihydrochloride is a Mnk2 and Mnk1 inhibitor (IC50 values are 575 and 646 nM respectively). Exhibits selectivity against a panel of 24 protein Ki nases, including those upstream of Mnk1/2.
价 格:¥电议型 号:T41165产 地:中国大陆
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T41158MS 39N;MS 39NMS 39N
MS 39N is a negative control for MS 39. Binds EGFR without inducing degradation.
价 格:¥电议型 号:T41158产 地:中国大陆
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T41058Nelonemdaz potassiumNelonemdaz potassiumNeu2000potassium|||Salfaprodil
Nelonemdaz potassium (also known as Salfaprodil) is a potent NR2B-selective and uncompetitive antagonist of N-methyl-D-aspartate (NMDA). This compound exhibits remarkable neuroprotection against cell death induced by both NMDA and free radicals, in addition to its role as a free radical scavenger.
价 格:¥电议型 号:T41058产 地:中国大陆
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T40958Milategrast;MilategrastE6007;E6007
Milategrast is a chemical compound that functions as a potent cell adhesion inhibitor and cell infiltration inhibitor. In vitro studies have demonstrated its ability to effectively inhibit the adhesion of Jurkat cells to human fibronectin, with an IC50 value of less than 5 μM.
价 格:¥电议型 号:T40958产 地:中国大陆
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T40869Moxonidine hydrochloride;盐酸莫索尼定BDF5895hydrochloride;BDF5895hydrochloride|||盐酸莫索尼定
Moxonidine Hydrochloride serves as a selective agonist for the imidazoline receptor subtype 1 and functions as an antihypertensive agent. It primarily acts within the central nervous system and demonstrates a significant preference for I1 imidazoline receptors over α2-adrenoceptors, with a 40-fold higher affinity. This compound effectively reduces stimulated norepinephrine overflow, indicating its potent efficacy. Despite similar agents like AGN192403 targeting the same receptor, moxonidine&acut
价 格:¥电议型 号:T40869产 地:中国大陆
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T40858NH2-PEG2-C6-Cl;化合物NH2-PEG2-C6-ClNH2-PEG2-C6-Cl;NH2-PEG2-C6-Cl
NH2-PEG2-C6-Cl is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T40858产 地:中国大陆
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T40758Hydrastinine;HydrastinineHydrastinine
Hydrastinine, a key alkaloid component found in Hydrastis canadensis (goldenseal), serves as an effective hemostatic agent.
价 格:¥电议型 号:T40758产 地:中国大陆
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T40738CAY10580;CAY10580CAY10580;CAY10580
CAY10580 is a potent and selective prostaglandin EP 4 receptor agonist ( K i =35 nM).
价 格:¥电议型 号:T40738产 地:中国大陆
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T40658[D-Asn5]-Oxytocin;[D-Asn5]-Oxytocin[D-Asn5]-Oxytocin;[D-Asn5]-Oxytocin
[D-Asn5]-Oxytocin exhibits minimal specific oxytocic and vasodepressor effects. Comparative cumulative dose-response investigations reveal that [D-Asn5]-Oxytocin demonstrates a similar intrinsic activity to oxytocin in terms of oxytocic activity.
价 格:¥电议型 号:T40658产 地:中国大陆