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T80100Ovotransferrin (328-332);化合物 Ovotransferrin (328-332)Ovotransferrin (328-332)
Ovotransferrin (328-332), with an IC50 of 20 μM, exhibits protective activity against hypertension by inhibiting the Angiotensin-Converting Enzyme (ACE) and also displays anti-Cholinesterase (ChE) activity, suggesting a potential role in the treatment of Alzheimer´s disease [1] [2].
价 格:¥电议型 号:T80100产 地:中国大陆
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T8010Dibutyl sebacate;癸二酸二丁酯Dibutyl decanedioate;Dibutyl decanedioate|||癸二酸二丁酯
Dibutyl sebacate (Dibutyl decanedioate) is an organic chemical which is mainly used as a plasticizer in the production of plastics.
价 格:¥电议型 号:T8010产 地:中国大陆
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T80010(25S)-Antcin B;化合物 (25S)-Antcin B(25S)-Antcin B
Antcin-B exhibits a high-affinity inhibition of 3CLPro, which is potentially significant in SARS-CoV-2 research [1].
价 格:¥电议型 号:T80010产 地:中国大陆
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T79010Lp-PLA2-IN-12;化合物 Lp-PLA2-IN-12Lp-PLA2-IN-12
Lp-PLA2-IN-12 (compound 19), an Lp-PLA2 inhibitor, is utilized in researching neurodegenerative diseases including Alzheimer´s disease (AD), glaucoma, age-related macular degeneration (AMD), and cardiovascular conditions such as atherosclerosis [1].
价 格:¥电议型 号:T79010产 地:中国大陆
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T78982BK60106;化合物 BK60106BK60106
BK60106, a CD99 inhibitor, selectively targets and binds to the extracellular domain of CD99, effectively inducing apoptosis in Ewing sarcoma (ES) cells with minimal associated DNA damage [1].
价 格:¥电议型 号:T78982产 地:中国大陆
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T78657Azilsartan mepixetil potassium;化合物 Azilsartan mepixetil potassiumQR-01019K;QR-01019K
Azilsartan medoxomil potassium (QR-01019K), an angiotensin II receptor antagonist, exhibits a potent and sustained antihypertensive effect, along with a more pronounced and enduring reduction in heart rate, and a high safety profile. It shows promise for investigation in the management of hypertension, chronic heart failure, and diabetic nephropathy[1].
价 格:¥电议型 号:T78657产 地:中国大陆
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T78127Tisolagiline;化合物 TisolagilineKDS2010;KDS2010
Tisolagiline (KDS2010), a reversible MAO-B inhibitor, is utilized in Parkinson´s disease research [1].
价 格:¥电议型 号:T78127产 地:中国大陆
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T78010L-GO-203 TFA;化合物 L-GO-203 TFAL-GO-203 TFA
L-GO-203 TFA is a potent inhibitor of the MUC1-C oncoprotein, serving as an anticancer peptide that targets intracellular proteins [1].
价 格:¥电议型 号:T78010产 地:中国大陆
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T77010Fiztasovimab;化合物 FiztasovimabFiztasovimab
Fiztasovimab (NPC-21; EV2038), a fully human IgG1λ monoclonal antibody (mAb), targets human cytomegalovirus (hCMV). It exerts its neutralizing activity through binding to the antigenic domain 1 of glycoprotein B on the hCMV envelope, effectively inhibiting cell-to-cell transmission of hCMV [1].
价 格:¥电议型 号:T77010产 地:中国大陆
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T76747Fletikumab;夫来库单抗Anti-IL-20|||NN-8226|||NNC 0109-0012;Anti-IL-20|||NN-8226|||NNC 0109-0012
Fletikumab (NNC0109-0012) is a monoclonal antibody against IL-20 that is often used as an IL-20 inhibitor.Fletikumab is used in the study of rheumatoid arthritis and psoriasis.
价 格:¥电议型 号:T76747产 地:中国大陆
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T76242MMI-0100;化合物 MMI-0100MMI-0100
MMI-0100, a cell-permeant peptide inhibitor of mitogen-activated protein kinase activated protein kinase II (MK2), effectively reduces intimal hyperplasia ex vivo and in vivo. It specifically suppresses IL-6 expression while not affecting IL-8 expression and mitigates fibrotic processes, including vein graft disease [1].
价 格:¥电议型 号:T76242产 地:中国大陆
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T76072LCCZ01048 TFA;化合物 CCZ01048 TFACCZ01048 TFA
CCZ01048 TFA, an α-MSH analogue, demonstrates a strong binding affinity for the melanocortin 1 receptor (MC1R), displaying a K i value of 0.31 nM. It exhibits rapid internalization into B16F10 melanoma cells and maintains high in vivo stability. CCZ01048 TFA holds potential as an effective agent for PET imaging of malignant melanoma [1].
价 格:¥电议型 号:T76072L产 地:中国大陆
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T76072CCZ01048;化合物 CCZ01048CCZ01048
CCZ01048, an analogue of α-melanocyte-stimulating hormone (α-MSH), demonstrates a high binding affinity for the melanocortin 1 receptor (MC1R), with a Ki of 0.31 nM. It rapidly internalizes into B16F10 melanoma cells and exhibits notable in vivo stability, making it a promising candidate for PET imaging of malignant melanoma [1].
价 格:¥电议型 号:T76072产 地:中国大陆
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T76010N-CBZ-Phe-Arg-AMC TFA;化合物 N-CBZ-Phe-Arg-AMC TFAN-CBZ-Phe-Arg-AMC TFA
N-CBZ-Phe-Arg-AMC (Z-FR-AMC) TFA serves as a substrate for cathepsin, facilitating the evaluation of lysosomal cathepsin enzyme activity [1] [2].
价 格:¥电议型 号:T76010产 地:中国大陆
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T75010TD1092;化合物 TD1092TD1092
TD1092, a pan-IAP degrader, effectively degrades cIAP1, cIAP2, and XIAP, catalyzing the activation of Caspase 3/7 and fostering apoptosis in cancer cells through IAP degradation. It also obstructs the TNFα-mediated NF-κB pathway, diminishing the phosphorylation of IKK, IkBα, p65, and p38, and operates as a PROTAC. This compound is utilized in cancer research [1].
价 格:¥电议型 号:T75010产 地:中国大陆
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T74874CpG ODN 10101;化合物 CpG ODN 10101ODN 10101;ODN 10101
CpG ODN 10101 (CPG 10101) is a novel potent and selective Toll-like receptor 9 (TLR9)-containing oligodeoxynucleotide agonist with antiviral activity for the treatment of chronic infections.
价 格:¥电议型 号:T74874产 地:中国大陆
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T74010(Rac)-Mono(3,5,5-trimethylhexyl) phthalate;化合物 (Rac)-Mono(3,5,5-trimethylhexyl) phthalate(Rac)-Mono(
(Rac)-Mono(3,5,5-trimethylhexyl) phthalate, a significant metabolite of widely utilized phthalate plasticizers, exhibits an immuno-suppressive effect [1].
价 格:¥电议型 号:T74010产 地:中国大陆
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T73512ZC0109;化合物 ZC0109ZC0109
ZC0109, a dual inhibitor targeting IDO1 and Thioredoxin Reductase 1 (TrxR1) with IC50 values of 50 nM and 3.0 μM respectively, effectively promotes ROS accumulation and arrests the cell cycle at the G1/S phase, culminating in apoptosis of cancer cells.
价 格:¥电议型 号:T73512产 地:中国大陆
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T73214RX 801077;化合物 RX 8010772 BFI free base;2 BFI free base
RX 801077 (2 BFI free base), a selective imidazoline I2 receptor (I2R) agonist, exhibits a K i value of 70.1 nM, demonstrating anti-inflammatory and neuroprotective properties. This compound holds research potential for traumatic brain injury (TBI).
价 格:¥电议型 号:T73214产 地:中国大陆
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T72010Dibenzosuberenol;化合物 DibenzosuberenolDibenzosuberenol
Dibenzosuberenol is a reactant involved in oxidation with tert-butylhydroperoxide in water for synthesis of carboxylic acids and ketones; Synthesis of tachykinin neurokinin-1 receptor antagonists; Pauson-Khand reaction mechanism studies; Mapping the active site of aziridination catalysts.
价 格:¥电议型 号:T72010产 地:中国大陆