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T40675CP-610431;CP-610431CP-610431
CP-610431 is a reversible, ATP-uncompetitive inhibitor of acetyl-CoA carboxylase (ACC), exhibiting isozyme nonselectivity. It inhibits both ACC1 and ACC2 with IC50 values of approximately 50 nM. CP-610431 offers potential application in metabolic syndrome research.
价 格:¥电议型 号:T40675产 地:中国大陆
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T40674Ioxaglic acid;碘克沙酸P-286;碘克沙酸|||P-286
Ioxaglic acid (P-286) is a negatively charged contrast agent commonly utilized as an inverse indicator for glycosaminoglycan (GAG) in computed tomography (CT). This compound is valuable for imaging human osteoarthritic cartilage, enabling the quantitative assessment of glycosaminoglycan content.
价 格:¥电议型 号:T40674产 地:中国大陆
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T40673Benzyl-PEG1-Ms;Benzyl-PEG1-MsBenzyl-PEG1-Ms;Benzyl-PEG1-Ms
Benzyl-PEG1-Ms is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T40673产 地:中国大陆
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T406717-Deaza-7-propargylamino-dGTP;7-Deaza-7-propargylamino-dGTP7-Deaza-7-propargylamino-dGTP
7-Deaza-7-propargylamino-dGTP is an analogue of dGTP, specifically designed for the purpose of gene sequencing.
价 格:¥电议型 号:T40671产 地:中国大陆
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T406707-Deaza-7-propargylamino-dATP;7-Deaza-7-propargylamino-dATP7-Deaza-7-propargylamino-dATP
7-Deaza-7-propargylamino-dATP is a deoxyadenosine triphosphate (dATP) analog utilized in the field of gene sequencing.
价 格:¥电议型 号:T40670产 地:中国大陆
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T4067VLX1570;化合物VLX1570VLX1570
VLX1570 is a competitive inhibitor of proteasome DUB activity with IC50 ranging from 4.2 uM to 8.6 uM. It has potent inhibition for USP14.
价 格:¥电议型 号:T4067产 地:中国大陆
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T40508LTRV120056 acetate;化合物TRV120056 acetateTRV120056 acetate (40678-47-5 Free base);TRV120056 acetate (40
TRV120056 acetate is a Gq-biased agonist with 10-fold greater molecular efficiency on AT1R-Gq fusion proteins than AT1R-βarr2 fusion proteins.
价 格:¥电议型 号:T40508L产 地:中国大陆
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T40067SENP1-IN-4SENP1-IN-4SENP1-IN-4
SENP1-IN-4, a distinct inhibitor of the deSUMOylation protease 1 (SENP1), is designed to enhance tumor radiosensitivity.
价 格:¥电议型 号:T40067产 地:中国大陆
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T3978Linerixibat;化合物GSK2330672GSK2330672|||Iinerixibat;GSK2330672|||Iinerixibat
Linerixibat (GSK2330672) is a highly effective, nonabsorbable ASBT inhibitor (IC50: 42 ± 3 nM). It can lower glucose in an animal model of type 2 diabetes and shows excellent developability properties.
价 格:¥电议型 号:T3978产 地:中国大陆
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T39633Navocaftor;NavocaftorGLPG 3067|||ABBV-3067;GLPG 3067|||ABBV-3067
Navocaftor, as a cystic fibrosis transmembrane regulator ( CFTR ), is a protein modulator (US 20200377491 Al, example 1).
价 格:¥电议型 号:T39633产 地:中国大陆
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T39498Tofersen;TofersenBIIB067|||ISIS-SOD1Rx;BIIB067|||ISIS-SOD1Rx
Tofersen (BIIB067) is an antisense oligonucleotide utilized to inhibit the synthesis of superoxide dismutase 1 (SOD1) protein by facilitating the degradation of SOD1 mRNA via the RNase H-dependent mechanism. This compound holds potential for amyotrophic lateral sclerosis (ALS) research.
价 格:¥电议型 号:T39498产 地:中国大陆
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T39067MAGE-3 (271-279);MAGE-3 (271-279)MAGE-3 (271-279)
MAGE-3 (271-279) is a peptide consisting of 271-279 amino acid residues that is derived from melanoma antigens encoded by the MAGE-3 gene. It is specifically recognized by cytolytic T lymphocytes (CTLs) and binds to the human leukocyte antigen (HLA)-A2 molecule. MAGE-3 is highly expressed in various human tumor types, such as malignant melanoma, but not in normal tissues, except for the testis and placenta.
价 格:¥电议型 号:T39067产 地:中国大陆
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T38369CAY10678化合物 CAY10678CAY-10678|||CAY10678
CAY10678 is an mPGES-1 inhibitor that inhibits PD-1.CAY10678 reduces collagen deposition and T-cell depletion, and may be used to study melanoma.CASHIPS
价 格:¥电议型 号:T38369产 地:中国大陆
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T380675,6-dehydro Arachidonic Acid;5,6-dehydro Arachidonic Acid5,6-dehydro Arachidonic Acid
5,6-dehydro Arachidonic acid is an analog of arachidonic acid with an acetylene in the 5,6 position. It inhibits 5-LO in rat basophilic leukemia cells, with a Ki value of 15 μM. In guinea pig leukocytes, 5-LO is inhibited by 5,6-dehydro arachidonic acid with an IC50 value of 10 μM.
价 格:¥电议型 号:T38067产 地:中国大陆
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T370679-hydroxy Stearic Acid;9-羟基十八酸9-hydroxy Stearic Acid
9-hydroxy Stearic Acid is a hydroxy fatty acid that is the active metabolite of 9-PAHSA. 9-hydroxy Stearic Acid is formed from 9-PAHSA through carboxyl ester lipase in the liver and pancreas. The 9-hydroxy Stearic Acid (5 μM) was stearic acid, which inhibited the expression of histone deacetylase 1 (HDAC1) in the lysate of HT-29 colon cancer cells. 3. When the concentration was 100 μM.1, the proliferation of HT-29 cells was inhibited and cell cycle arrest was induced in G0/ g1 phase.
价 格:¥电议型 号:T37067产 地:中国大陆
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T3663Eliglustat;依利格鲁司特GENZ-112638|||Genz 99067;GENZ-112638|||Genz 99067|||依利格鲁司特
Eliglustat (Genz 99067) is an oral inhibitor of glucosylceramide synthase which is used in the therapy of type 1 Gaucher disease.
价 格:¥电议型 号:T3663产 地:中国大陆
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T36067Bongkrekic acid;米酵菌酸Bongkrek Acid;Bongkrek Acid
Bongkrekic acid (Bongkrekic Acid (ammonium salt)) is a mitochondrial toxin secreted by Burkholderia gladioli that inhibits adenine nucleotide translocase (ANT).Bongkrekic acid Bongkrekic acid Bongkrekic acid induces extracellular traps in neutrophils through signaling mediated by p38, ERK, PAD4, and P2X1.
价 格:¥电议型 号:T36067产 地:中国大陆
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T35897ASK120067;ASK120067ASK120067
ASK120067 is a potent and orally active inhibitor of EGFRT790M (IC50:0.3 nM) with selectivity over EGFRWT (IC50:6.0 nM). ASK120067 is a third-generation EGFR-TKI for the research of non-small cell lung cancer (NSCLC)[1].
价 格:¥电议型 号:T35897产 地:中国大陆
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T35819CAY10677CAY10677CAY10677|||CAY-10677
CAY10677 has a wide range of applications in life science related research.
价 格:¥电议型 号:T35819产 地:中国大陆