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T76890Petosemtamab派森妥单抗MCLA 158
Petosemtamab (MCLA 158) is a highly potent monoclonal antibody against EGFR (Kd: 0.22 nM) and LGR5 (Kd: 0.86 nM). Petosemtamab promotes EGFR signaling disruption and receptor breakdown in LGR5+ cancer cells. Petosemtamab can be used in the study of solid tumors such as head and neck squamous cell carcinoma (HNSCC) and metastatic colorectal cancer (CRC).
价 格:¥电议型 号:T76890产 地:中国大陆
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T76158Phosphate acetyltransferase;化合物 Phosphate acetyltransferasePhosphate acetyltransferase
Phosphate acetyltransferase, a transferase enzyme utilized in biochemical research, catalyzes the reversible acetylation of CoA from acetyl-P, yielding acetyl-CoA and inorganic phosphate. This process is integral to acetate assimilation/dissimilation reactions [1].
价 格:¥电议型 号:T76158产 地:中国大陆
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T75158Olpasiran;化合物 OlpasiranOlpasiran
Olpasiran is a small interfering RNA that reduces lipoprotein(a) synthesis in the liver.
价 格:¥电议型 号:T75158产 地:中国大陆
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T74158Aβ Fibrillization modulator 1;化合物 Aβ Fibrillization modulator 1Aβ Fibrillization modulator 1
Aβ Fibrillization Modulator 1 stabilizes amyloid-beta (Aβ) monomers, preventing their aggregation into fibrils.
价 格:¥电议型 号:T74158产 地:中国大陆
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T7370Talarozole;他拉罗唑R115866;R115866|||他拉罗唑
Talarozole (R115866) is an oral systemic all-trans retinoic acid metabolism blocking agent (RAMBA). Talarozole inhibits both CYP26A1 and CYP26B1 with IC50s of 5.4 and 0.46 nM, respectively.Talarozole for the treatment of acne, psoriasis and other keratinization disorders.
价 格:¥电议型 号:T7370产 地:中国大陆
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T71589AS15;化合物 AS15AS15
AS15 is a novel covalent nanomolar inhibitor of protein disulfide isomerase (PDI).
价 格:¥电议型 号:T71589产 地:中国大陆
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T71588Batanopride HCl;化合物 Batanopride HClBatanopride HCl
Batanopride is a antiemetic 5-HT3 receptor antagonist.
价 格:¥电议型 号:T71588产 地:中国大陆
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T71587Fluoxetine succinate ester;化合物 Fluoxetine succinate esterFluoxetine succinate ester
Fluoxetine succinate ester is an antidepressant of the selective serotonin reuptake inhibitor (SSRI) class. It is used for the treatment of major depressive disorder, obsessive–compulsive disorder, bulimia nervosa, panic disorder, and premenstrual dysphoric disorder.
价 格:¥电议型 号:T71587产 地:中国大陆
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T71586Z-VAE(OMe)-fmk;化合物 Z-VAE(OMe)-fmkZ-VAE(OMe)-fmk
Z-VAE(OMe)-fmk is a cell-permeable and irreversible UCHL1 inhibitor. The inhibitor approaches the active-site cleft from the opposite side of the crossover loop as compared to the direction of approach of ubiquitin´s C-terminal tail, thereby occupying the P1´ (leaving group) site, a binding site perhaps used by the unknown C-terminal extension of ubiquitin in the actual in vivo substrate(s) of UCHL1.
价 格:¥电议型 号:T71586产 地:中国大陆
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T71585DB03417;化合物 DB03417DB03417
DB03417 is a compound listed in web page: https://go.drugbank.com/drugs/DB03417. DB03417 is a potential tryptase inhibitor.
价 格:¥电议型 号:T71585产 地:中国大陆
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T71584Microtubule Inhibitor 185322;化合物 Microtubule Inhibitor 185322Microtubule Inhibitor 185322
Microtubule inhibitor 185322 is an inhibitor of microtubule assembly, inducung mitotic arrest and apoptosis of MM cells.
价 格:¥电议型 号:T71584产 地:中国大陆
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T71583Amlodipine hydrochloride, (R)-;化合物 Amlodipine hydrochloride, (R)-Amlodipine hydrochloride, (R)-
Amlodipine hydrochloride, (R)-, is a medication used to lower blood pressure and prevent chest pain. It belongs to a group of medications known as dihydropyridine-type calcium channel blockers. By widening of blood vessels it lowers blood pressure. In angina, amlodipine increases blood flow to the heart muscle to relieve pain due to angina.
价 格:¥电议型 号:T71583产 地:中国大陆
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T71582Niguldipine Free Base;化合物 Niguldipine Free BaseNiguldipine Free Base
Niguldipine Free Base is a calcium channel blocker and a?-adrenergic receptor antagonist and a clinical modulator of multidrug resistance.
价 格:¥电议型 号:T71582产 地:中国大陆
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T71581SGX393;化合物 SGX393SGX393
SGX393 is an inhibitor of the CML mutant Bcr-AblT315I, thereby preempting in vitro resistance when combined with nilotinib or dasatinib.
价 格:¥电议型 号:T71581产 地:中国大陆
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T71580EBV activator C60;化合物 EBV activator C60EBV activator C60
EBV activator C60 is an EBV activator, and a well-performing EBV lytic cycle inducer.
价 格:¥电议型 号:T71580产 地:中国大陆
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T7158Ombitasvir;奥比他韦ABT-267;奥比他韦|||ABT-267
Ombitasvir (ABT-267) is an orally bioavailable and potent inhibitor of the hepatitis C virus (HCV) non-structural protein 5A (NS5A).with EC50s of 0.82 to 19.3 pM against HCV genotypes 1 to 5, and 366 pM against genotype 6a
价 格:¥电议型 号:T7158产 地:中国大陆
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T71577KOS-1584;化合物 KOS-1584KOS-1584
KOS-1584 is a second-generation epothilone with potential antineoplastic activity. Epothilone KOS-1584 binds to tubulin and induces microtubule polymerization and stabilizes microtubules against depolymerization, which may result in the inhibition of cell division, the induction of G2/M arrest, and apoptosis. Compared to first-generation epothilones, this agent exhibits greater safety and efficacy with an enhanced pharmaceutical profile, including enhanced water solubility and tumor penetration,
价 格:¥电议型 号:T71577产 地:中国大陆
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T71158Org 31806;化合物 Org 31806Org 31806
Org 31806 is a progestational hormone antagonist.
价 格:¥电议型 号:T71158产 地:中国大陆
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T70928CB-1158-analog;化合物 CB-1158-analogCB-1158-analog
CB-1158-analog, also known as Numidargistat-analog and INCB01158-analog, is a potent and orally active arginase inhibitor with IC50=89 nM) . CB-1158 blocked myeloid cell-mediated suppression of T cell proliferation in vitro and reduced tumor growth in multiple mouse models of cancer, as a single agent and in combination with checkpoint blockade, adoptive T cell therapy, adoptive NK cell therapy, and the chemotherapy agent gemcitabine. CB-1158 increased tumor-infiltrating CD8+ T cells and NK cell
价 格:¥电议型 号:T70928产 地:中国大陆
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T70081Pd 158771;化合物 Pd 158771Pd 158771
Pd 158771 is a D2 and 5-HT1A agonist.
价 格:¥电议型 号:T70081产 地:中国大陆