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  • T68385Zenidolol;化合物 ZenidololICI-118551;ICI-118551

    Zenidolol (ICI-118551), a selective β2 adrenergic receptor antagonist, demonstrates inhibition of β2-, β1-, and β3-adrenergic receptors with K i values of 0.7, 49.5, and 611 nM, respectively. It is employed as an ocular hypotensive agent in ophthalmic disease research.

    价 格:¥电议型 号:T68385产 地:中国大陆

  • T68185U 66985;化合物 U 66985U 66985

    U 66985 is a Platelet-activating factor (PAF) receptor antagonist that inhibit the electrophysiological effects of PAF.

    价 格:¥电议型 号:T68185产 地:中国大陆

  • T6749A-1331852;化合物A1331852A-1331852

    A-1331852 is a potent and selectiveBCL-XL inhibitor and may be useful in the treatment of cancer, immune and autoimmune diseases.

    价 格:¥电议型 号:T6749产 地:中国大陆

  • T66185Fmoc-Lys(Tfa)-OH;化合物 Fmoc-Lys(Tfa)-OHFmoc-Lys(Tfa)-OH

    Fmoc-Lys(Tfa)-OH is a useful organic compound for research related to life sciences. The catalog number is T66185 and the CAS number is 76265-69-5.

    价 格:¥电议型 号:T66185产 地:中国大陆

  • T65185(R)-2-(1-(((9H-Fluoren-9-yl)methoxy)carbonyl)pyrrolidin-2-yl)acetic acid;化合物 (R)-2-(1-(((9H-Fluoren-

    (R)-2-(1-(((9H-Fluoren-9-yl)methoxy)carbonyl)pyrrolidin-2-yl)acetic acid is a useful organic compound for research related to life sciences. The catalog number is T65185 and the CAS number is 193693-61-7.

    价 格:¥电议型 号:T65185产 地:中国大陆

  • T64185TAM&Met-IN-1;化合物 TAM&Met-IN-1TAM&Met-IN-1

    TAM&Met-IN-1 is a potent inhibitor of TAM and c-Met, acting on AXL (IC50: 6.1 nM), MER (IC50: 13.2 nM) and TYRO3 (IC50: 21.6 nM). TAM&Met-IN-1 can be used in anticancer studies.

    价 格:¥电议型 号:T64185产 地:中国大陆

  • T64000MRTX-EX185;化合物 MRTX-EX185MRTX-EX185

    MRTX-EX185 is an effective inhibitor of GDP-loaded KRAS and KRAS (G12D) with an IC50=90 nM for KRAS (G12D). MRTX-EX185 is also capable of binding GDP-loaded HRAS.

    价 格:¥电议型 号:T64000产 地:中国大陆

  • T63930DI-1859;化合物 DI-1859DI-1859

    DI-1859 is a selective, potent and covalent inhibitor of DCN1. At low nanomolar concentrations, DI-1859 inhibits the neddylation of cullin 3 in cells. DI-1859 induces a significant increase in NRF2 protein, a CRL3 substrate, in mouse liver and effectively protects mice from acetaminophen-induced liver injury.

    价 格:¥电议型 号:T63930产 地:中国大陆

  • T6375Alibendol阿利苯多cebera|||EB 1856|||阿利苯多

    Alibendol (cebera) is a choleretic, antispasmodic, and cholekinetic.

    价 格:¥电议型 号:T6375产 地:中国大陆

  • T63185EGFR-IN-47;化合物 EGFR-IN-47EGFR-IN-47

    EGFR-IN-47 is a potent, orally active inhibitor of EGFRL858R/T790M/C797S (IC50: 0.01 μM). EGFR-IN-47 is capable of blocking the cell cycle and inducing apoptosis. EGFR-IN-47 has potential for NSCLC studies.

    价 格:¥电议型 号:T63185产 地:中国大陆

  • T62851SLF1081851 TFA;化合物 SLF1081851 TFASLF1081851 TFA

    SLF1081851 (TFA) is a Spns2 inhibitor with an IC50 value of 1.93 μM for inhibition of S1P release.SLF1081851 (TFA) plays a key role in development and the immune system.

    价 格:¥电议型 号:T62851产 地:中国大陆

  • T62185GABA-AT-IN-1;化合物 GABA-AT-IN-1GABA-AT-IN-1

    GABA-AT-IN-1 (Compound 6) is an inhibitor of γ-aminobutyric acid transaminase (GABA-AT) that crosses the blood-brain barrier.

    价 格:¥电议型 号:T62185产 地:中国大陆

  • T61859MK-28;化合物 MK-28MK-28

    MK-28 is a selective PERK agonist that reduces toxicity and prolongs survival in a Huntington´s disease model.MK-28 has a significant killing effect on MK28 gastric cancer cells.

    价 格:¥电议型 号:T61859产 地:中国大陆

  • T61858HDAC8-IN-3;化合物 HDAC8-IN-3HDAC8-IN-3

    HDAC8-IN-3 (compound P19) is a highly potent inhibitor of HDAC8, displaying an IC50 value of 9.3 μM and producing thermal stabilization. Moreover, HDAC8-IN-3 exhibits cytotoxicity and induces apoptosis specifically in leukemic cell lines [1].

    价 格:¥电议型 号:T61858产 地:中国大陆

  • T61857DNA-PK-IN-4;化合物 DNA-PK-IN-4DNA-PK-IN-4

    DNA-PK-IN-4 (WO2021209055A1, compound 27), an imidazolinone derivative compound, is a highly effective inhibitor of DNA-PK, specifically targeting DNA-PKcs activity. By inhibiting DNA-PKcs, the compound significantly impairs tumor DNA repair mechanisms and triggers apoptosis in cells. With its potential application in cancer research, DNA-PK-IN-4 holds promise for further investigation [1].

    价 格:¥电议型 号:T61857产 地:中国大陆

  • T61856Antiviral agent 10;化合物 Antiviral agent 10Antiviral agent 10

    Antiviral agent 10 effectively inhibits the respiratory syncytial virus (RSV) [1], serving as a potent anti-viral compound.

    价 格:¥电议型 号:T61856产 地:中国大陆

  • T61855Antistaphylococcal agent 1;化合物 Antistaphylococcal agent 1Antistaphylococcal agent 1

    Antistaphylococcal agent 1 is an antistaphylococcal therapeutic agent.

    价 格:¥电议型 号:T61855产 地:中国大陆

  • T61853Antimycobacterial agent-1;化合物 Antimycobacterial agent-1Antimycobacterial agent-1

    Antimycobacterial agent-1 (compound 33) demonstrates potent antimycobacterial activity against Mycobacterium tuberculosis H37Ra, with a minimal inhibitory concentration (MIC) value of 1 μg/ml. Notably, antimycobacterial agent-1 exhibits low cytotoxicity in normal cells, as evidenced by an IC50 value of 143.2 μg/ml in Vero cells [1].

    价 格:¥电议型 号:T61853产 地:中国大陆

  • T61852hCAIX-IN-8;化合物 hCAIX-IN-8hCAIX-IN-8

    hCAIX-IN-8 (compound 7i) is a highly potent and selective inhibitor of hCAIX, demonstrating potent inhibitory activity against CAIX with an IC50 value of 0.024 μM. It also exhibits inhibitory activity against CAII and CAVA with IC50 values of 1.99 μM and 1.10 μM, respectively. Furthermore, hCAIX-IN-8 exhibits anti-proliferative effects and low toxicity. It effectively reduces the occurrence of epithelial-to-mesenchymal transitions and promotes apoptosis. Additionally, hCAIX-IN-8 effectively inhi

    价 格:¥电议型 号:T61852产 地:中国大陆

  • T61851PTP1B-IN-3 diammonium;化合物 PTP1B-IN-3 diammoniumPTP1B-IN-3 diammonium

    PTP1B-IN-3 diammonium is a highly effective and orally bioavailable inhibitor of the protein tyrosine phosphatase 1B (PTP1B) enzyme, with an IC50 value of 120 nM for both PTP1B and TCPTP. This compound exhibits potent antidiabetic and anticancer properties, as supported by extensive research [1] [2].

    价 格:¥电议型 号:T61851产 地:中国大陆

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