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  • T38714Boc-NH-PPG2；Boc-NH-PPG2Boc-NH-PPG2；Boc-NH-PPG2

    Boc-NH-PPG2 is a alkyl/ether-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

    价 格：￥电议型 号：T38714产 地：中国大陆

  • T38622Bcl-xL antagonist 2；Bcl-xL拮抗剂2Bcl-xL antagonist 2

    Bcl-xL antagonist 2 is an effective and selective antagonist of Bcl-xL with an IC50 of 91 nM and a Ki of 65 nM. Bcl-xL antagonist 2 induces apoptosis in cancer cells and can be used in studies about chronic lymphocytic leukemia and non-Hodgkin’s lymphoma.

    价 格：￥电议型 号：T38622产 地：中国大陆

  • T38159STING Agonist 12b；STING Agonist 12bSTING Agonist 12b

    STING agonist 12b is an agonist of stimulator of interferon genes (STING).1It binds to STING (Kd= 26.4 μM) and induces interferon reporter gene expression in cells expressing human or mouse STING (EC50s = 7.45 and 10.23 μM, respectively). STING agonist 12b (40 μM) induces expression of TNF-a, IL-6, IP-10, and IL-1b in THP-1 cells.

    价 格：￥电议型 号：T38159产 地：中国大陆

  • T38093NT1-O12B；NT1-O12BNT1-O12B；NT1-O12B

    NT1-O12B, an endogenous neurotransmitter-derived lipidoid (NT-lipidoid), serves as a highly efficient carrier for enhancing the transportation of various blood-brain barrier (BBB)-impermeable cargos to the brain. Incorporating NT1-O12B into BBB-impermeable lipid nanoparticles (LNPs) enables these LNPs to effectively traverse the BBB. In addition to enabling cargo passage through the BBB, NT-lipidoid formulations facilitate efficient delivery of the cargo into neuronal cells for purposes such as

    价 格：￥电议型 号：T38093产 地：中国大陆

  • T37793A2B receptor antagonist 2；化合物A2B receptor antagonist 2A2B receptor antagonist 2；A2B receptor antagon

    A2B receptor antagonist 2 is an antagonist of adenosine receptor A2B (Ki = 2.30 μM for rA1, 6.8 μM for rA2A, 3.44 μM for hA2B).

    价 格：￥电议型 号：T37793产 地：中国大陆

  • T3708BP-1-102；化合物BP-1-102BP-1-102

    BP-1-102 is an orally active, effective and specific STAT3 inhibitor. BP-1-102 binds Stat3 (Kd: 504 nM), then blocks Stat3-phosphotyrosine (pTyr) peptide interactions and Stat3 activation (4-6.8 μM), and selectively inhibits migration, survival, growth, and invasion of Stat3-dependent tumor cells. The BP-1-102-mediated inhibition of aberrantly active Stat3 in tumor cells suppresses the expression of c-Myc, Bcl-xL, Cyclin D1, Survivin, and VEGF.

    价 格：￥电议型 号：T3708产 地：中国大陆

  • T36801Binucleine 2Binucleine 2Binucleine 2

    Binucleine 2 is an isoform-specific and ATP-competitive inhibitor of Drosophila Aurora B kinase (Ki = 0.36 μM), a kinase involved in cell division. It is specific for Drosophila Aurora B kinase, inhibiting it in a dose-dependent manner, with minimal inhibition of human or X. laevis Aurora B kinases at concentrations up to 100 μM. Binucleine 2 induces mitotic and cytokinesis defects in Drosophila Kc167 cells. It prevents Drosophila S2 cells from assembling a contractile ring during cell division

    价 格：￥电议型 号：T36801产 地：中国大陆

  • T36706Bottromycin A2；Bottromycin A2Bottromycin A2

    Bottromycin A2is an antibiotic originally isolated fromStreptomyces.1It blocks the binding of aminoacyl-tRNA to the A site of the 50S ribosome, inhibiting protein synthesis.2Bottromycin A2is active against clinical isolates of methicillin-resistantStaphylococcus aureus(MRSA) and vancomycin-resistantEnterococciwith MIC values of 1 and 0.5 μg/ml, respectively.

    价 格：￥电议型 号：T36706产 地：中国大陆

  • T36577K-Biotin-W-Histone H2B (108-125) (trifluoroacetate salt)；K-Biotin-W-Histone H2B (108-125) (trifluoro

    Histone H2B (108-125) is a peptide fragment of histone H2B that corresponds to amino acid residues 109-126 of the human histone H2B sequence. It contains an N-terminal biotinylated lysine followed by a tryptophan linker. Histone H2B can be modified by addition of an O-linked N-acetylglucosamine (GlcNAc) moiety to the serine residue at position 112, which promotes monoubiquitination of the lysine at position 120.1 Both of these modifications are associated with active transcription. Histone H2B a

    价 格：￥电议型 号：T36577产 地：中国大陆

  • T36095Histone H2BK12ac (1-22)-GGK-biotin amide (trifluoroacetate salt)；Histone H2BK12ac (1-22)-GGK-biotin

    Histone H2BK12ac (1-22)-GGK-biotin amide (trifluoroacetate salt) can be used in related research in the field of life sciences, and its product number is T36095.

    价 格：￥电议型 号：T36095产 地：中国大陆

  • T3599BFH772化合物BFH772BFH-722

    BFH772, a structure analogue of BAW2881, is a potent and selective VEGF inhibitor. BFH772 is highly effective at targeting VEGFR2 kinase with an IC50 value of 3 nM. BFH772 inhibits the ligand induced autophosphorylation of RET, PDGFR, and KIT kinases, with IC50 values ranging between 30 and 160 nM.

    价 格：￥电议型 号：T3599产 地：中国大陆

  • T35924Tat-NR2Baa；Tat-NR2BaaTat-NR2Baa；Tat-NR2Baa

    Tat-NR2BAA is an inactive control peptide of Tat-NR2B9c. It shares a similar sequence with Tat-NR2B9c, but possesses a double-point mutation in the COOH terminal tSXV motif. This mutation renders Tat-NR2BAA unable to bind PSD-95. Tat-NR2B9c, on the other hand, is a membrane-permeable peptide that interferes with PSD-95/NMDAR binding. This interference leads to the decoupling of NR2B- and/or NR2A-type NMDARs from PSD-95[1][2].

    价 格：￥电议型 号：T35924产 地：中国大陆

  • T35868BCAT-IN-2；BCAT 抑制剂2BCAT-IN-2

    BCAT-IN-2 is an orally active and selective inhibitor of mitochondrial branched-chain aminotransferase (BCATm), inhibits BCATm and BCATc, and is used in obesity and dyslipidemia.

    价 格：￥电议型 号：T35868产 地：中国大陆

  • T35476BSJ-04-132；BSJ-04-132BSJ-04-132

    Selective Cdk4 degrader. Degrades Cdk4 in Molt-4 cells, with no effect on Cdk6 levels. Displays cereblon-dependent degradation.

    价 格：￥电议型 号：T35476产 地：中国大陆

  • T3518GSK269962A；化合物GSK269962AGSK269962B|||GSK 269962|||GSK269962A HCl；GSK269962B|||GSK 269962|||GSK269962

    GSK269962A (GSK269962A HCl) is a selective ROCK(Rho-associated protein kinase) inhibitor with IC50 values of 1.6 and 4 nM for ROCK1 and ROCK2, respectively.

    价 格：￥电议型 号：T3518产 地：中国大陆

  • T34722Streptothricin E；化合物 T34722BRN 4286375；BRN 4286375

    Streptothricin E is a biochemical.

    价 格：￥电议型 号：T34722产 地：中国大陆

  • T34278Redaporfin化合物 T34278F 2BMet|||F2BMet|||F-2BMet|||LUZ11|||LUZ 11|||LUZ-11

    Redaporfin, also known as F-2BMet or LUZ-11, is a photosensitizer for Photodynamic Therapy (PDT) of cancer. Redaporfin showed a high efficacy in the treatment of male BALB/c mice with subcutaneously implanted colon (CT26) tumours. Vascular-PDT with 1.5 mg/kg redaporfin and a light dose of 74 J/cm? led to the complete tumour regression in 83% of the mice.

    价 格：￥电议型 号：T34278产 地：中国大陆

  • T32062Heptenophos；化合物 T32062BRN 1978448|||BRN1978448|||BRN-1978448；BRN 1978448|||BRN1978448|||BRN-1978448

    Heptenophos is a biochemical.

    价 格：￥电议型 号：T32062产 地：中国大陆

  • T31887Fungiqual；化合物 T31887Heliofor P|||Mikephor BN|||Tinopal 2BF|||Tinopal 2B|||Kayaphor BSN；Heliofor P|||

    Fungiqual is a bioactive chemical.

    价 格：￥电议型 号：T31887产 地：中国大陆

  • T31292Decalin；化合物 T31292bicyclo[4.4.0]decane|||decahydronaphthalene；bicyclo[4.4.0]decane|||decahydronaphth

    Decalin (decahydronaphthalene, also known as bicyclo[4.4.0]decane), a bicyclic organic compound, is an industrial solvent. A colorless liquid with an aromatic odor, it is used as a solvent for many resins or fuel additives. It is the saturated analog of naphthalene and can be prepared from it by hydrogenation in the presence of a catalyst. Decahydronaphthalene easily forms explosive organic peroxides upon storage in the presence of air.

    价 格：￥电议型 号：T31292产 地：中国大陆

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