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T3909Pulsatilla saponin D;白头翁皂苷DHederacolchiside A|||SB365;白头翁皂苷D|||Hederacolchiside A|||SB365
Pulsatilla saponin D (Hederacolchiside A) has exhibited potential beneficial effects as a chemopreventive agent for critical health conditions including cancer, and it inhibits cell growth via cell cycle arrest and apoptosis in various cancer cell types.
价 格:¥电议型 号:T3909产 地:中国大陆
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T39089Acid secretion-IN-1;Acid secretion-IN-1Acid secretion-IN-1
Acid secretion-IN-1, a polycyclic compound, is synthesized for its application as an IDO inhibitor in synthetic experiments.
价 格:¥电议型 号:T39089产 地:中国大陆
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T39088Mc-Dexamethasone;Mc-DexamethasoneMc-Dexamethasone
Mc-Dexamethasone is a drug-linker conjugate for ADC . Mc-Dexamethasone is made toxin Dexamethasone conjugated to the non-cleavable MC linker. Dexamethasone is a glucocorticoid receptor agonist.
价 格:¥电议型 号:T39088产 地:中国大陆
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T39087MC-VC-PAB-NH2;MC-VC-PAB-NH2MC-VC-PAB-NH2;MC-VC-PAB-NH2
MC-VC-PAB-NH2 is a cleavable linker vital in ADC synthesis. MC-VC-PAB-NH2 joins cytotoxic drugs to antibodies, enabling precise delivery to cells or proteins. The cleavable nature ensures controlled drug release, optimizing ADC effectiveness.
价 格:¥电议型 号:T39087产 地:中国大陆
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T39086MK-4688;MK-4688MK-4688
MK-4688 is an efficient inhibitor of the HDM2-p53 protein-protein interaction.
价 格:¥电议型 号:T39086产 地:中国大陆
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T39083Propargyl-PEG9-acid;Propargyl-PEG9-acidPropargyl-PEG9-acid;Propargyl-PEG9-acid
Propargyl-PEG9-acid is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T39083产 地:中国大陆
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T39082AL-611;AL-611AL-611
AL-611 is an HCV NS5B polymerase inhibitor ( EC 50 = 5 nM).
价 格:¥电议型 号:T39082产 地:中国大陆
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T39081A 410099.1, amine-Boc;A 410099.1, amine-BocA 410099.1, amine-Boc
A-410099.1, also known as amine-Boc, serves as a functionalized IAP ligand instrumental in the synthesis of PROTACs, including those targeting BTK (specifically PROTACs 4 and 5).
价 格:¥电议型 号:T39081产 地:中国大陆
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T39080Escin Ie;Escin IeEscin Ie
Escin Ie is a derivative of Aescine in Aesculi Semen extract.
价 格:¥电议型 号:T39080产 地:中国大陆
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T390810-Gingerol10-姜酚10-姜酚
10-Gingerol-induced apoptosis was accompanied by phosphorylation of the mitogen-activated protein kinase (MAPKs) family, p38 MAPK (p38), c-Jun N-terminal kinase (JNK), and extracellular signal-regulated kinase (ERK).
价 格:¥电议型 号:T3908产 地:中国大陆
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T39078CXCR7 antagonist-1;CXCR7拮抗剂1CXCR7 antagonist-1;CXCR7 antagonist-1
CXCR7 antagonist-1 is a specific antagonist of the binding of the SDF-1 chemokine or I-TAC to the chemokine receptor CXCR7. CXCR7 antagonist-1 prevents tumor cell proliferation and tumor formation and can be used in studies about inflammatory diseases.
价 格:¥电议型 号:T39078产 地:中国大陆
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T39076Benzyl-PEG8-THP;Benzyl-PEG8-THPBenzyl-PEG8-THP;Benzyl-PEG8-THP
Benzyl-PEG8-THP is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T39076产 地:中国大陆
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T39075Bis-PEG3-t-butyl esterBis-PEG3-t-butyl esterBis-PEG3-t-butyl ester
Bis-PEG3-t-butyl ester is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T39075产 地:中国大陆
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T39074(Rac)-Zevaquenabant;(Rac)-Zevaquenabant(Rac)-MRI-1867|||(Rac)-Zevaquenabant;(Rac)-MRI-1867|||(Rac)-Z
(Rac)-Zevaquenabant ((Rac)-MRI-1867, compound 6b) is a potent and selective antagonist of the cannabinoid receptor type 1 (CB1R) and inducible nitric oxide synthase (iNOS), exhibiting a binding affinity (Ki) of 5.7 nM specifically for CB1R. Due to its characteristics, (Rac)-Zevaquenabant holds promise as an investigative tool in liver fibrosis research.
价 格:¥电议型 号:T39074产 地:中国大陆
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T39073Amredobresib;AmredobresibAmredobresib
Amredobresib is a potent BET inhibitor that impedes the interaction between bromodomains and acetylated lysines on histone H3 and H4, thereby serving as crucial regulators of gene transcription. It proves valuable in the investigation of acute myeloid leukemia (AML) and cancer.
价 格:¥电议型 号:T39073产 地:中国大陆
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T39071Thailanstatin D;Thailanstatin DThailanstatin D
Thailanstatin D, an analogue of Thailanstatin A, inhibits AR-V7 gene splicing by disrupting the interaction between U2AF65 and SAP155, hindering their binding to the polypyrimidine tract situated between the branch point and the 3´ splice site. This compound displays potent tumor inhibitory properties in human castration-resistant prostate cancer (CRPC) xenografts, resulting in cellular apoptosis.
价 格:¥电议型 号:T39071产 地:中国大陆
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T390704-Succinimidyl-oxycarbonyl-α-(2-pyridyldithio)toluene;4-Succinimidyl-oxycarbonyl-α-(2-pyridyldithio)
4-Succinimidyl-oxycarbonyl-α-(2-pyridyldithio)toluene is a non-cleavable linker employed during the synthesis of antibody-drug conjugates (ADCs).
价 格:¥电议型 号:T39070产 地:中国大陆
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T3907Tenuigenin;远志皂苷元Senegenin|||Senegin;Senegenin|||Senegin|||远志皂苷元
Tenuigenin (Senegenin) is a natural product from Polygala tenuifolia used in Chinese medicine with antioxidative and anti-inflammatory activity.
价 格:¥电议型 号:T3907产 地:中国大陆
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T39068Fomivirsen sodium;Fomivirsen sodiumFomivirsen sodium
Fomivirsen sodium is an antisense 21 mer phosphorothioate oligonucleotide. Fomivirsen is an antiviral agent that is used cytomegalovirus retinitis (CMV) research, incluiding in AIDs. Fomivirsen sodium binds to and degrades the mRNAs encoding CMV immediate-early 2 protein (required for viral replication), thus providing bioactive effects for CMV retinitis by inhibition of virus proliferation.
价 格:¥电议型 号:T39068产 地:中国大陆
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T39067MAGE-3 (271-279);MAGE-3 (271-279)MAGE-3 (271-279)
MAGE-3 (271-279) is a peptide consisting of 271-279 amino acid residues that is derived from melanoma antigens encoded by the MAGE-3 gene. It is specifically recognized by cytolytic T lymphocytes (CTLs) and binds to the human leukocyte antigen (HLA)-A2 molecule. MAGE-3 is highly expressed in various human tumor types, such as malignant melanoma, but not in normal tissues, except for the testis and placenta.
价 格:¥电议型 号:T39067产 地:中国大陆