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产品数:86101
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T6971Ro 5126766MAPKK,CH 5126766,MEK,Ro 5126766,Raf kinases,Raf,Mitogen-activated protein kinase kinase,in
RO5126766 (CH5126766) is a dual RAF/MEK inhibitor with IC50 of 8.2 nM, 19 nM, 56 nM, and 160 nM for BRAF V600E, BRAF, CRAF, and MEK1, respectively. Phase 1.
价 格:¥电议型 号:T6971产 地:中国大陆
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T9142MRT68921 dihydrochlorideinhibit,MRT 68921,ULK,MRT-68921 dihydrochloride,Inhibitor,MRT68921,Unc-51 li
MRT68921 dihydrochloride is a potent ULK1 and ULK2 inhibitor (IC50 of 2.9 nM and 1.1 nM, respectively).
价 格:¥电议型 号:T9142产 地:中国大陆
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TJS03417-Amino-4-(trifluoromethyl)coumarinCoumarin151,7Amino4(trifluoromethyl)coumarin,Coumarin-151,7 Amino
7-Amino-4-(trifluoromethyl)coumarin is a 5-Hydroxytryptamine Receptor Subtype 1E (HTR1E) antagonist. 7-Amino-4-(trifluoromethyl)coumarin is a Galanin Receptor 2 (GALR2) antagonist. 7-Amino-4-(trifluoromethyl)coumarin is a galanin receptor 2 (GalR2) antagonist. 7-Amino-4-(trifluoromethyl)coumarin is a HSD17B4, hydroxysteroid (17-beta) dehydrogenase 4 inhibitor with the activity value of 21 uM.
价 格:¥电议型 号:TJS0341产 地:中国大陆
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T7512BMS-191011Potassium Channel,rodent models of stroke,Panc-1,neuroprotective activity,inhibit,IGR39,BM
BMS-191011 is an activator of large-conductance calcium-activated potassium (BKCa) channels ,effective in stroke models
价 格:¥电议型 号:T7512产 地:中国大陆
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TN5137TetramethylkaempferolTetramethylkaempferol
Tetramethylkaempferol is a PPARγ agonist, it can improve insulin sensitivity by increasing the levels of adiponectin, an important adipocytokine associated with insulin sensitivity in adipose tissue. Tetramethylkaempferol can concentration-dependently enhance the accumulation of triglyceride, a marker of adipogenesis.
价 格:¥电议型 号:TN5137产 地:中国大陆
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TN67511-HEXACOSANOL1HEXACOSANOL,1 HEXACOSANOL
Hexacosanol activates AMPK and hepatic autophagy and inhibits SREBP2, resulting in hypocholesterolemic activities and improvement of hepatic steatosis.
价 格:¥电议型 号:TN6751产 地:中国大陆
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T95141-Dodecanol1-Dodecanol,1Dodecanol,1 Dodecanol,inhibit,Endogenous Metabolite,Inhibitor
1-Dodecanol is an endogenous metabolite and a saturated fatty alcohol from coconut oil fatty acids. It has a floral odor and is used in detergents, Lepidopteran pheromone/sex attractant, lubricating oils, pesticides and pharmaceuticals.
价 格:¥电议型 号:T9514产 地:中国大陆
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T9512Linoleyl alcoholFatty,Linoleyl alcohol,Alcohol,lipoxygenase,inhibit,Inhibitor
Linoleyl alcohol, fatty alcohol, is a structural analog of Linoleic acid with no a-carboxyl group[1].
价 格:¥电议型 号:T9512产 地:中国大陆
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T8551NitrobenzylthioinosineAdenosine Receptor,Inhibitor,adenosine,neuroprotective,P1 receptor,BBB,inhibit
Nitrobenzylthioinosine is an inhibitor of ENT1 transporter that binds to ENT1 transporter with high affinity.
价 格:¥电议型 号:T8551产 地:中国大陆
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T10268AGX51ubiquitin,AGX 51,Inhibitor,AGX51,anti-tumor,TNBC,AGX-51,inhibit
AGX51 is an antagonist of inhibitor of DNA binding (ID) proteins. AGX51 treatment lead to pan-Id degradation, cell cycle arrest, and cell death.
价 格:¥电议型 号:T10268产 地:中国大陆
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T8951JTP 0819958 - HOIPIN-1JTP 0819958 HOIPIN1,JTP 0819958 HOIPIN 1
JTP-0819958 is a selective linear ubiquitin chain assembly complex (LUBAC) inhibitor with an IC50 of 2.8 μM[1]. JTP-0819958 suppress LUBAC-mediated NF-kB activation in vitro[2].
价 格:¥电议型 号:T8951产 地:中国大陆
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T6840LFRAX486 HCL(1232030-35-1 free base)FRAX486 HCL(1232030351 free base),FRAX486 HCL(1232030 35 1 free b
FRAX486 HCL is a potent p21-activated kinase (PAK) inhibitor with IC50 values of 14, 33, 39 and 575 nM for PAK1, PAK2, PAK3 and PAK4 respectively.
价 格:¥电议型 号:T6840L产 地:中国大陆
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T7951TBK1/IKKε-IN-5I kappa B kinase,Inhibitor,inhibit,IKK,IκB kinase,TBK1/IKKε IN 5,TBK-1/IKKε-IN-5,TBK1/
TBK1/IKKε-IN-5 is a dual TBK1 and IKKε inhibitor(IC50 of 1 nM and 5.6 nM, respectively).
价 格:¥电议型 号:T7951产 地:中国大陆
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T9636DalpiciclibMCF7,BT-474/T,Cyclin dependent kinase,Eca 109,MCF7/TR,and KYSE-510 ESCC,SHR6390,Inhibitor
Dalpiciclib is a highly selective, orally bioavailable, and comparable potency inhibitor of CDK4 and CKD6 with IC50s of 12.4?nM and 9.9?nM, respectively. Dalpiciclib exerts potent antitumor activity in esophageal squamous cell carcinoma by inhibiting phosphorylated tumor suppressor retinoblastoma protein (Rb) and inducing G1 cell cycle arrest.
价 格:¥电议型 号:T9636产 地:中国大陆
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T23549YM 511YM 511
YM 511 is a highly specific non-steroidal aromatase inhibitor. YM 511 inhibits aromatase activities in microsomes from rat ovary and human placenta competitively (IC50s of 0.4 and 0.12 nM, respectively). YM 511 slightly inhibits production of other steroid hormones. YM 511 has the potential for suppressing estrogen-dependent action research without affecting serum levels of other steroid hormones.
价 格:¥电议型 号:T23549产 地:中国大陆
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T95101,2-Distearoyl-sn-glycero-3-phosphorylcholineinhibit,lipid,liposomes,1,2Distearoylsnglycero3phosphor
L-ALPHA-PHOSPHATIDYLCHOLINE, DISTEAROYL is a cylindrical-shaped lipid used to synthesize liposomes. L-ALPHA-PHOSPHATIDYLCHOLINE, DISTEAROYL is the lipid component in the lipid nanoparticle (LNP) system.
价 格:¥电议型 号:T9510产 地:中国大陆
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T26646AQW051
AQW051 is an orally active alpha-7 nicotinic acetylcholine receptor (α7-nAChR) specific activator that interacts with recombinant human α7-nAChR expression (pKD value 7.56). Alpha7-nachr is considered an attractive target for the treatment of cognitive impairments associated with neurological disorders, so VQW-051 is often used in studies of anxiety disorders and acute anxiety.
价 格:¥电议型 号:T26646产 地:中国大陆
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T8519Raphin1 acetateRaphin1,Phosphatase,Raphin-1 acetate,Raphin-1,Raphin1 acetate,Raphin 1,inhibit,Inhibi
Raphin1 acetate is a selective and orally bioavailable regulatory phosphatase PPP1R15B (R15B) inhibitor.
价 格:¥电议型 号:T8519产 地:中国大陆
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T8676FOY 251SARS-CoV,inhibit,proteinase,Threonine proteases,metabolism,Serine endopeptidases,FOY 251,obes
FOY 251 is a proteinase inhibitor, and is an anti-proteolytic active metabolite camostate.
价 格:¥电议型 号:T8676产 地:中国大陆