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TP1956LPKC ζ pseudosubstrate acetatePKC ζ pseudosubstrate acetate
PKC ζ pseudosubstrate acetate is an inhibitor of protein kinase C (PKC) ζ; attached to cell permeabilisation Antennapedia domain vector peptide. Consists of amino acids 113 - 129 of PKC ζ pseudosubstrate domain linked by a disulphide bridge to the Antennapedia domain vector peptide. The Antennapedia peptide is actively taken up by intact cells, at 4 or 37°C, ensuring rapid and effective uptake of the inhibitor peptide. Once inside the cell, the disulphide bonds are subjected to reduction in the
价 格:¥电议型 号:TP1956L产 地:中国大陆
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T12758Ro 25-6981Ro 256981,Ro 25 6981
Ro 25-6981 is a potent and selective activity-dependent NMDA receptors blocker containing the NR2B subunit with IC50s of 0.009 and 52 μM for cloned receptor subunit combinations NR1C/NR2B and NR1C/NR2A respectively. Ro 25-6981 can be used in studies about Parkinson´s disease.
价 格:¥电议型 号:T12758产 地:中国大陆
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T8567amflutizoleamflutizole
Amflutizole used for the treatment of gout, and is a Xanthine oxidase inhibitor
价 格:¥电议型 号:T8567产 地:中国大陆
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T6S2356Corynolineinhibit,Corynoline,Inhibitor,Cholinesterase (ChE),Keap1-Nrf2
1. Corynoline is an acetylcholinesterase inhibitor.
价 格:¥电议型 号:T6S2356产 地:中国大陆
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T16856SB228357SB-228357,SB228357
SB228357 is a potent and selective antagonist of the 5-HT receptor with pKis of 6.9, 8.0, and 9.0 for 5-HT2A, 5-HT2B, and 5-HT2C, respectively.
价 格:¥电议型 号:T16856产 地:中国大陆
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T9256N-Cyclohexyl-4-[1-(1-piperazinyl)-2,6-naphthyridin-3-yl]-2-pyridinamineNCyclohexyl4[1(1piperazinyl)2
N-Cyclohexyl-4-[1-(1-piperazinyl)-2,6-naphthyridin-3-yl]-2-pyridinamine is a novel 2,6-naphthyridine identified by high throughput screen (HTS) as a dual protein kinase C/D (PKC/PKD) inhibitor[1].
价 格:¥电议型 号:T9256产 地:中国大陆
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T34656SKLB 1028
SKLB1028 is a new type of oral multikinase inhibitor of EGFR, FLT3, and Abl. It shows excellent activity in FLT3-driven AML models and considerable potency in CML models containing Abl mutants.
价 格:¥电议型 号:T34656产 地:中国大陆
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TP1074LNeuropeptide FF acetate(99566-27-5 free base)Neuropeptide FF acetate(99566275 free base),Neuropeptid
NPFF acetate is an octapeptide belonging to the RF amide family. NPFF interacts with G-protein-coupled receptors NPFF (1) and NPFF (2).
价 格:¥电议型 号:TP1074L产 地:中国大陆
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T22192BMS 195614
BMS 195614 is a selective RARα antagonist. BMS 195614 can bind to the RARα subunit.
价 格:¥电议型 号:T22192产 地:中国大陆
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T9560MAO-B-IN-2MAO B IN 2,MAOBIN2
MAO-B-IN-2 is a selective and competitive inhibitor of MAO-B and BChE with IC 50 values of 0.51 and 7.00 μM, respectively. MAO-B-IN-2 attenuates H2O2-induced cellular damage via good ROS scavenging property.
价 格:¥电议型 号:T9560产 地:中国大陆
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TN2256Taccalonolide Binhibit,Taccalonolide B,Microtubule/Tubulin,Inhibitor
Taccalonolide B is effective in vitro against cell lines that overexpress P-glycoprotein (Pgp) and multidrug-resistance protein (MRP7). Taccalonolide B inhibits growth of SK-OV-3 cells with an IC50 of 208 nM.
价 格:¥电议型 号:TN2256产 地:中国大陆
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T8656CAY10404Bcl-XL,CAY10404,cancer,COX,anti-inflammatory,Bcl-2,Apoptosis,Akt,H-1703,Cyclooxygenase,NSCLC
CAY10404 is a potent and highly selective inhibitor of COX-2 and COX-1. It is also a potent inhibitor of PKB/Akt and MAPK signalling pathways and induces apoptosis in NSCLC cells, with analgesic, anti-inflammatory and anti-cancer activities.
价 格:¥电议型 号:T8656产 地:中国大陆
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T8559GALNON TFA(475115-35-6(free base))GALNON TFA(475115356(free base)),GALNON TFA(475115 35 6(free base)
Galnon is a novel non-peptide galanin receptor agonist (GAL1 and GAL2 with Ki of 11.7 and 34.1 μM respectively).
价 格:¥电议型 号:T8559产 地:中国大陆
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TP1600LIα52 acetate(137756-45-7 free base)Iα52 acetate(137756457 free base),Iα52 acetate(137756 45 7 free b
Iα52 acetate is a naturally processed peptide encompassed the residues 52-68 of the murine I-Eα chain and may contribute to selection of immature T cells.
价 格:¥电议型 号:TP1600L产 地:中国大陆
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T9565OSBPL7-IN-1OSBPL7,orally active,ABCA1,OSBPL7 IN 1,Inhibitor,OSBPL-7-IN-1,OSBPL7IN1,inhibit
OSBPL7-IN-1 is an orally active inhibitor of oxysterol binding protein like 7 (OSBPL7). OSBPL7-IN-1 promotes an increase of ABCA1 at the plasma membrane without affecting mRNA expression[1].
价 格:¥电议型 号:T9565产 地:中国大陆
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T6856Halofuginoneosteoarthritis,collagen-1,Na+ channels,Calcium Channel,Na channels,Transforming growth f
Halofuginone, the competitive inhibitor of prolyl-tRNA synthetase(Ki=18.3 nM), could also down-regulate Smad3 and blocked TGF-β signaling at 10 ng/ml in the mammal.
价 格:¥电议型 号:T6856产 地:中国大陆
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T23509VU 0285683VU 0285683
VU 0285683 is a specific negative allosteric modulator of mGluR5 with a high affinity for the MPEP binding site. VU 0285683 shows anxiolytic-like activity.
价 格:¥电议型 号:T23509产 地:中国大陆
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T7795RIPA-56RIPA-56,inhibit,Receptor-interacting protein kinases,RIP kinase,RIPK,Inhibitor,RIPA 56,RIPA56
RIPA-56 is an inhibitor of RIP1
价 格:¥电议型 号:T7795产 地:中国大陆
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TP1866Lβ-amyloid 1-11 acetate(190436-05-6 free base)βamyloid 111 acetate(190436056 free base),β amyloid 1 1
β-amyloid 1-11 acetate is a fragment of Amyloid-β peptide, maybe used in the research of neurological disease.
价 格:¥电议型 号:TP1866L产 地:中国大陆