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  • T62145PXYD3；化合物 PXYD3PXYD3

    PXYD3 is a ribosomal protein S1 (RpsA) antagonist that acts on RpsA-CTD (Kd: 5.66 μM) and RpsA-CTD Δ438A (Kd: 6.91 μM). RpsA plays an important role in the translocation of Mycobacterium tuberculosis (Mtb).

    价 格：￥电议型 号：T62145产 地：中国大陆

  • T62144HBV-IN-13；化合物 HBV-IN-13HBV-IN-13

    HBV-IN-12 is a potent inhibitor of hepatitis B surface antigen (HBsAg).

    价 格：￥电议型 号：T62144产 地：中国大陆

  • T62143LP-922761 hydrate；化合物 LP-922761 hydrateLP-922761 hydrate

    LP-922761 hydrate is a selective, potent, orally active AAK1 inhibitor with IC50 values of 4.8 nM and 7.6 nM in enzyme and cellular assays, respectively. LP-922761 hydrate inhibits BMP-2 inducible protein kinase (BIKE) (IC50: 24 nM). 922761 hydrate has no significant effect on cellular GAK, opioids, adrenergic α2 or GABAa receptors.

    价 格：￥电议型 号：T62143产 地：中国大陆

  • T62142COX-2-IN-17；化合物 COX-2-IN-17COX-2-IN-17

    COX-2-IN-17 is a potent, blood-brain barrier permeable COX-2 (cyclooxygenase-2) inhibitor (IC50: 0.02 μM) with anti-inflammatory and analgesic activity.

    价 格：￥电议型 号：T62142产 地：中国大陆

  • T62141RBP4 ligand-1；化合物 RBP4 ligand-1RBP4 ligand-1

    RBP4 ligand-1 is a non-retinoid ligand for retinol-binding protein 4 (RBP4). hRBP4SPAIC50 and RBP4-TTR FRET IC50 values were 0.23±0.11 and 0.13±0.12 μM for the radioligand binding assay and FRET assay, respectively. 0.12 μM.

    价 格：￥电议型 号：T62141产 地：中国大陆

  • T62140HF50731；化合物 HF50731HF50731

    HF50731 is a potent antagonist of CXCR4. HF50731 has a strong binding affinity for CXCR4 (IC50: 19.8 nM). HF50731 utilizes the CXCR4 co-receptor and effectively inhibits calcium mobilization (IC50: 119.2 nM), cell migration (IC50: 621.4 nM) and HIV-1 infection (IC50: 1.5 nM). IC50: 1.5 nM).

    价 格：￥电议型 号：T62140产 地：中国大陆

  • T6214Emtricitabine恩曲他滨恩曲他滨|||FTC|||Emtriva|||BW1592

    Emtricitabine (FTC) (FTC), a nucleoside reverse transcriptase inhibitor, exhibits inhibition activity against human immunodeficiency virus (HIV) and hepatitis B virus.

    价 格：￥电议型 号：T6214产 地：中国大陆

  • T62139NDT-30805；化合物 NDT-30805NDT-30805

    NDT-30805 is a triazolopyridine derivative that inhibits the release of IL-1β from PBMC (IC50: 0.013 μM).NDT-30805 is also a selective inhibitor of the NLRP3 inflammasome.NDT-30805 can be used to study inflammation and immunity.

    价 格：￥电议型 号：T62139产 地：中国大陆

  • T62138Renin inhibitor-1；化合物 Renin inhibitor-1Renin inhibitor-1

    Renin inhibitor-1 (compound 26) is a potent, orally active renin inhibitor capable of acting on rh-renin (IC50: 0.9 nM) and hPRA (IC50: 1.8 nM). renal disease.

    价 格：￥电议型 号：T62138产 地：中国大陆

  • T62137ANKRD22-IN-1；化合物 ANKRD22-IN-1ANKRD22-IN-1

    ANKRD22-IN-1 is a potent inhibitor of ANKRD22, which promotes the expansion of gastrointestinal mucosal epithelial stem cells and thus indirectly activates the Wnt classical pathway, which is beneficial for the recovery of damaged gastrointestinal mucosal tissue in vivo.

    价 格：￥电议型 号：T62137产 地：中国大陆

  • T62135Tubulin polymerization-IN-25；化合物 Tubulin polymerization-IN-25Tubulin polymerization-IN-25

    Tubulin polymerization-IN-25 is a selective, dual tubulin polymerization (IC50: 1.11 μM) and farnesyl transferase (FTase) (IC50: 0.39 μM) inhibitor. polymerization-IN-25 exhibits cytotoxicity against cancer cells and blocks cell proliferation.

    价 格：￥电议型 号：T62135产 地：中国大陆

  • T62134A1/A3 AR antagonist 1；化合物 A1/A3 AR antagonist 1A1/A3 AR antagonist 1

    A1/A3 AR antagonist 1 (Compound 10) is a potent, dual adenosine 1 (A1) and adenosine 3 (A3) receptor antagonist that acts on human A1 (Ki: 37.6 nM), human A3 (Ki: 25.4 nM) and rat A1 (Ki: 1.47 nM). 1 Can be used to study renal failure, inflammatory lung disease and Alzheimer´s disease.

    价 格：￥电议型 号：T62134产 地：中国大陆

  • T62133TRPC5 modulator-1；化合物 TRPC5 modulator-1TRPC5 modulator-1

    TRPC5 modulator-1 (Compound 9) is a TRPC5 modulator (IC50<1 nM) that can be used to study neuropsychiatric disorders.

    价 格：￥电议型 号：T62133产 地：中国大陆

  • T62132S-777469；化合物 S-777469S-777469

    S-777469 is a selective, orally active agonist of the cannabinoid type 2 receptor (CB2) (Ki: 36 nM). s-777469 significantly inhibited compound 48/80-induced scratching behaviour in mice in a dose-dependent manner. s-777469 excites CB2, inhibits pruritic signalling and shows an anti-pruritic effect.

    价 格：￥电议型 号：T62132产 地：中国大陆

  • T62131α-Synuclein inhibitor 5；化合物 α-Synuclein inhibitor 5α-Synuclein inhibitor 5

    α-Synuclein inhibitor 5 is a potent inhibitor of α-Synuclein (α-Syn) aggregation across the blood-brain barrier (IC50: 1.22 μM), with 94.3% inhibition at 30 μM.

    价 格：￥电议型 号：T62131产 地：中国大陆

  • T62130IDO-IN-16；化合物 IDO-IN-16IDO-IN-16

    IDO-IN-16 (compound 5) is an IDO inhibitor (IC50: 36 nM).

    价 格：￥电议型 号：T62130产 地：中国大陆

  • T62129HIV-1 inhibitor-16；化合物 HIV-1 inhibitor-16HIV-1 inhibitor-16

    HIV-1 inhibitor-16 (compound 7a) is a potent HIV-1 inhibitor with an EC50 of 1.3 nM against wild-type HIV-1. HIV-1 inhibitor-16 also showed some inhibitory activity against HIV-1 K103N, E138K, Y181C and L100I strains with EC50s of 5.4 nM, 9.2 nM, 22 nM and 35 nM, respectively. HIV-1 inhibitor-16 showed good solubility and hepatic microsomal stability and did not exhibit significant CYP enzyme inhibitory activity or acute toxicity.

    价 格：￥电议型 号：T62129产 地：中国大陆

  • T62128AMG8788；化合物 AMG8788AMG8788

    AMG8788 is a selective, potent and orally active TRPM8 antagonist (IC50: 63.2 nM).

    价 格：￥电议型 号：T62128产 地：中国大陆

  • T62127AMPA-IN-1；化合物 AMPA-IN-1AMPA-IN-1

    AMPA-IN-1 is a potent inhibitor of AMPA receptors, a widely expressed receptor in the brain with a central role in the regulation of rapid excitatory synaptic transmission and synaptic plasticity. 14).

    价 格：￥电议型 号：T62127产 地：中国大陆

  • T62126(Rac)-NMDAR antagonist 1；化合物 (Rac)-NMDAR antagonist 1(Rac)-NMDAR antagonist 1

    (Rac)-NMDAR antagonist 1 is a racemate of NMDAR antagonist 1. NMDAR antagonist 1 is a potent, orally active, NR2B-selective NMDAR antagonist.

    价 格：￥电议型 号：T62126产 地：中国大陆

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