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T62950IRAK4-IN-18；化合物 IRAK4-IN-18IRAK4-IN-18
IRAK4-IN-18 is a potent inhibitor of interleukin 1 receptor-associated kinase 4 (IRAK4) (IC50: 15 nM). IRAK4-IN-18 inhibits LPS-induced IL23 production in THP and DC cells and blocks the development of arthritis in rats, a model of arthritis. IRAK4-IN-18 can be used to study arthritic diseases.
价 格：￥电议型 号：T62950产 地：中国大陆
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T6295Dabigatran；达比加群BIBR 953|||BIBR 953ZW；BIBR 953|||BIBR 953ZW|||达比加群
Dabigatran (BIBR 953ZW) is a THROMBIN inhibitor which acts by binding and blocking thrombogenic activity and the prevention of thrombus formation. It is used to reduce the risk of stroke and systemic EMBOLISM in patients with nonvalvular atrial fibrillation.
价 格：￥电议型 号：T6295产 地：中国大陆
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T62949(1R,3S)-THCCA-Asn；化合物 (1R,3S)-THCCA-Asn(1R,3S)-THCCA-Asn
(1R,3S)-THCCA-Asn (4j) is a selective inhibitor of thrombin (IC50: 0.07-0.14 μM) with anti-thrombotic effects.
价 格：￥电议型 号：T62949产 地：中国大陆
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T62948PI3Kβ-IN-1；化合物 PI3Kβ-IN-1PI3Kβ-IN-1
PI3Kβ-IN-1 is a selective, orally active PI3Kβ inhibitor (IC50: 2 nM).
价 格：￥电议型 号：T62948产 地：中国大陆
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T62947Lp-PLA2-IN-11；化合物 Lp-PLA2-IN-11Lp-PLA2-IN-11
Lp-PLA2-IN-11 is a potent inhibitor of lipoprotein-associated phospholipase A2 (Lp-PLA2). Lp-PLA2-IN-11 has the potential to be investigated in diseases associated with Lp-PLA2 activity (e.g. atherosclerosis, Alzheimer´s disease).
价 格：￥电议型 号：T62947产 地：中国大陆
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T62946Dopamine D3 receptor antagonist-2；化合物 Dopamine D3 receptor antagonist-2Dopamine D3 receptor antagoni
Dopamine D3 receptor antagonist-2 is a dopamine D3 receptor selective (Ki=2.16 nM) or multi-targeting dual ligand that shows potential effects in CNS disorders.
价 格：￥电议型 号：T62946产 地：中国大陆
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T62945Aurora A/PKC-IN-1；化合物 Aurora A/PKC-IN-1Aurora A/PKC-IN-1
Aurora A/PKC-IN-1 (Compound 2e) is a potent dual inhibitor of Aurora A (AurA) and PKC (α, β1, β2, θ), acting on AurA (IC50: 6.9 nM) and PKCα (IC50: 16.9 nM). Aurora A/PKC-IN-1 showed anti-proliferative and anti-metastatic effects on breast cancer cells.
价 格：￥电议型 号：T62945产 地：中国大陆
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T62944CCR8 antagonist 2；化合物 CCR8 antagonist 2CCR8 antagonist 2
CCR8 antagonist 2 is a potent antagonist of CCR8 that inhibits the activity of CCR8 (C-C Motif chemokine receptor 8), which is predominantly expressed on Treg and Th2 cells, and not on Th1 cells. CCR8 antagonist 2 can be used for the treatment of CCR8-mediated diseases (e.g. cancer and/or neuropathic pain).
价 格：￥电议型 号：T62944产 地：中国大陆
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T62943ZLWT-37；化合物 ZLWT-37ZLWT-37
ZLWT-37 is a potent, orally active inhibitor of CDKs, acting on CDK9 (IC50: 0.002 μM) and CDK2 (IC50: 0.054 μM). ZLWT-37 is capable of blocking the cell cycle of HCT116 cells in G2/M phase and apoptosis.
价 格：￥电议型 号：T62943产 地：中国大陆
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T62942Moricizine Hydrochloride；化合物 Moricizine HydrochlorideMoricizine Hydrochloride
Moricizine Hydrochloride (EN 313) is an orally active class I antiarrhythmic agent that reduces the maximum rate of phase 0 depolarisation; increases the repolarisation rate of phases 2 and 3, reduces the duration of action potentials and reduces the effective non-response period.
价 格：￥电议型 号：T62942产 地：中国大陆
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T62941Bcl-2/Mcl-1-IN-3；化合物 Bcl-2/Mcl-1-IN-3Bcl-2/Mcl-1-IN-3
Bcl-2/Mcl-1-IN-3 is a Bcl-2/Mcl-1 inhibitor that acts on Mcl-1 (Ki: 0.14 μM) and Bcl-2 (Ki: 0.23 μM) and can be used in cancer research.
价 格：￥电议型 号：T62941产 地：中国大陆
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T6294NVP-BSK805 2HCl (1092499-93-8(free base))；化合物NVP-BSK805 2HClNVP-BSK805 dihydrochloride|||BSK 805|||N
NVP-BSK805 2HCl (1092499-93-8(free base)) (BSK 805)(IC50=0.5 nM), a specific and effective ATP-competitive JAK2 inhibitor, is more than 20-fold specificity over JAK1, JAK3 and TYK2.
价 格：￥电议型 号：T6294产 地：中国大陆
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T62939SHR2415；化合物 SHR2415SHR2415
SHR2415 is a selective, potent, orally active inhibitor of ERK1/2. SHR2415 inhibits ERK1 (IC50: 2.8 nM) and ERK2 (IC50: 5.9 nM). SHR2415 exhibits high potency in Colo205 cells (IC50: 44.6 nM). SHR2415 can be used in cancer research.
价 格：￥电议型 号：T62939产 地：中国大陆
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T62938GNE-617 hydrochloride；化合物 GNE-617 hydrochlorideGNE-617 hydrochloride
GNE-617 hydrochloride is a specific inhibitor of NAMPT and inhibits NAMPT activity (IC50: 5 nM).
价 格：￥电议型 号：T62938产 地：中国大陆
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T62937MAGLi 432；化合物 MAGLi 432MAGLi 432
MAGLi 432 is a potent, highly selective, non-covalent, reversible (MAGL) inhibitor that binds with high affinity to the MAGL active site, with IC50 values of 4.2 nM (human enzyme) and 3.1 nM (mouse enzyme), MAGLi 432 can be used to study neurological disorders such as chronic inflammation, multiple sclerosis, blood-brain barrier dysfunction, Alzheimer´s disease and Parkinson´s disease.
价 格：￥电议型 号：T62937产 地：中国大陆
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T62936Antimalarial agent 8；化合物 Antimalarial agent 8Antimalarial agent 8
Antimalarial agent 8 (Compound 7e) is a novel, orally active antimalarial agent that is effective against P. falciparum in vitro and effective orally in an in vivo mouse model of malaria (40 mg/kg).
价 格：￥电议型 号：T62936产 地：中国大陆
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T62935Anticancer agent 26；化合物 Anticancer agent 26Anticancer agent 26
Anticancer agent 26 is a promising candidate for cancer therapy and deserves further development.
价 格：￥电议型 号：T62935产 地：中国大陆
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T62934ZLHQ-5f；化合物 ZLHQ-5fZLHQ-5f
ZLHQ-5f is a dual inhibitor of CDK2 and Topo I, acting on CDK2/CycA2 (IC50: 0.145 μM). ZLHQ-5f has a good safety profile by blocking the cell cycle of HCT116 cells in S phase and inducing apoptosis.
价 格：￥电议型 号：T62934产 地：中国大陆
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T62933ERK1/2 inhibitor 7；化合物 ERK1/2 inhibitor 7ERK1/2 inhibitor 7
ERK1/2 inhibitor 7 is a potent inhibitor of ERK, acting on ERK2 (IC50: 0.94 nM).
价 格：￥电议型 号：T62933产 地：中国大陆
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T62932NS2B/NS3-IN-2；化合物 NS2B/NS3-IN-2NS2B/NS3-IN-2
NS2B/NS3-IN-2 is a potent, covalent inhibitor of dengue virus (DENV) NS2B/NS3 (IC50: 6.0 nM, Ki: 0.66 μM). NS2B/NS3-IN-2 significantly increases cell viability and is not cytotoxic.
价 格：￥电议型 号：T62932产 地：中国大陆
