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T64258gamma-secretase modulator 5;化合物 gamma-secretase modulator 5gamma-secretase modulator 5
gamma-secretase modulator 5 (compound 22d) is a gamma-secretase modulator (GSMs) that crosses the blood-brain barrier and exhibits an inhibitory effect on the production of the aggregated amyloid β peptide Aβ42 (IC50: 60 nM). gamma-secretase modulator 5 can be used in the study of Alzheimer´s disease. The gamma-secretase modulator 5 can be used to study Alzheimer´s disease.
价 格:¥电议型 号:T64258产 地:中国大陆
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T64257FXIa-IN-8;化合物 FXIa-IN-8FXIa-IN-8
FXIa-IN-8 is a potent and selective inhibitor of FXIa (IC50: 14.2 nM). FXIa-IN-8 exhibits anti-thrombotic effects and does not increase the risk of bleeding or significant toxicity sup>[1].
价 格:¥电议型 号:T64257产 地:中国大陆
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T64256Emapticap pegol;化合物 Emapticap pegolEmapticap pegol
Emapticap pegol is a pro-inflammatory chemokine C-C motif ligand 2 (CCL2) inhibitor. emapticap pegol is also a 40-nucleotide oligonucleotide aptamer that exhibits different forms of Spiegelmers (L-RNA aptamers) in human (NOX-E36) and mouse (mNOX-E36).
价 格:¥电议型 号:T64256产 地:中国大陆
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T64255EGFR-IN-48;化合物 EGFR-IN-48EGFR-IN-48
EGFR-IN-48 is a potent, orally active EGFR inhibitor that acts on EGFRd19/TM/CS (IC50: 0.193 nM), EGFRLR/TM/CS (IC50: 0.251 nM), EGFRWT (IC50: 10.4 nM). EGFR-IN-48 is also able to inhibit EGFR-IN-48 also inhibits the proliferation of BaF3EGFR del19/T790M/C797S cells (IC50: 1.526 nM) and PC-9EGFR del19/T790M/C797S cells (IC50: 66.7 nM).
价 格:¥电议型 号:T64255产 地:中国大陆
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T64254EGFR/HER2-IN-5;化合物 EGFR/HER2-IN-5EGFR/HER2-IN-5
EGFR/HER2-IN-5 is an irreversible, orally active dual inhibitor of EGFR activity (IC50: 0.6 nM). EGFR/HER2-IN-4 shows potent EGFR kinase inhibitory activity against L858R and T790M mutations. EGFR/HER2-IN-4 exhibits significant anti-tumour effects in vivo and can be used to study lung cancer.
价 格:¥电议型 号:T64254产 地:中国大陆
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T64253EGFR/HER2-IN-4;化合物 EGFR/HER2-IN-4EGFR/HER2-IN-4
EGFR/HER2-IN-4 is an irreversible, orally active dual inhibitor of EGFR activity (IC50: 0.6 nM). EGFR/HER2-IN-4 shows potent EGFR kinase inhibitory activity against L858R and T790M mutations. EGFR/HER2-IN-4 exhibits significant anti-tumour effects in vivo and can be used to study lung cancer.
价 格:¥电议型 号:T64253产 地:中国大陆
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T64252Efpeglenatide;化合物 EfpeglenatideEfpeglenatide
Efpeglenatide is a long-acting agonist of the glucagon-like peptide (GLP-1) receptor. efpeglenatide improves insulin sensitivity and slows weight loss in mice models of diabetes and obesity. efpeglenatide has been used in studies of type II diabetes.
价 格:¥电议型 号:T64252产 地:中国大陆
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T64251Diguanosine 5′-triphosphate lithium;化合物 Diguanosine 5′-triphosphate lithiumDiguanosine 5′-triphospha
Diguanosine 5′-triphosphate (Gp3G) lithium is a dinucleoside triphosphate and a virus-specific oligonucleotide.Diguanosine 5′-triphosphate lithium is required for the synthesis of RNA during transcription.
价 格:¥电议型 号:T64251产 地:中国大陆
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T64250Desirudin;化合物 DesirudinDesirudin
Desirudin (CGP 39393) is a thrombin inhibitor that inhibits thrombosis and venous stasis thrombosis.Desirudin can be used to study thrombocytopenia or platelet dysfunction associated with thrombocytopenia.
价 格:¥电议型 号:T64250产 地:中国大陆
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T6425BTZ043 Racemate;化合物BTZ043 RacemateBTZ044|||BTZ10526038|||Benzothiazinone 10526038;BTZ044|||BTZ105260
BTZ043 Racemate (Benzothiazinone 10526038) is a decaprenylphosphoryl-β-D-ribose 2´-epimerase (DprE1) inhibitor, used as a new antimycobacterial agent.
价 格:¥电议型 号:T6425产 地:中国大陆
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T64249CYP11B1-IN-2;化合物 CYP11B1-IN-2CYP11B1-IN-2
CYP11B1-IN-2 (compound 7aa) is a selective, orally active inhibitor of CYP11B1 that acts on human CYP11B1 (IC50: 9 nM) and rat CYP11B1 (IC50: 25 nM). CYP11B1-IN-2 can be used to study diseases caused by cortisol overload.
价 格:¥电议型 号:T64249产 地:中国大陆
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T64248Cyclic-di-GMP sodium;化合物 Cyclic-di-GMP sodiumCyclic-di-GMP sodium
Cyclic di-GMP sodium (c-di-GMP sodium) is a STING activator and a ubiquitous second messenger that regulates biofilm formation, motility and virulence of various bacteria.
价 格:¥电议型 号:T64248产 地:中国大陆
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T64247CREB-IN-1 TFA;化合物 CREB-IN-1 TFACREB-IN-1 TFA
CREB-IN-1 TFA is a potent, orally active CREB inhibitor with an IC50 value of 0.18 μM. CREB-IN-1 TFA exhibits inhibitory effects on the growth of breast cancer cells.
价 格:¥电议型 号:T64247产 地:中国大陆
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T64246Cinchonine monohydrochloride hydrate;化合物 Cinchonine monohydrochloride hydrateCinchonine monohydrochl
Cinchonine ((8R,9S)-Cinchonine) monohydrochloride hydrate is a natural and potent antimalarial agent and an inhibitor of human platelet aggregation. apoptosis in human hepatocellular carcinoma cells and inhibits adipogenesis.
价 格:¥电议型 号:T64246产 地:中国大陆
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T64245CDK8-IN-9;化合物 CDK8-IN-9CDK8-IN-9
CDK8-IN-9 (compound 22) is a potent inhibitor of type II CDK8 (IC50: 48.6 nM) and has shown inhibitory effects on tumour growth. CDK8-IN-9 can be used to study colorectal cancer.
价 格:¥电议型 号:T64245产 地:中国大陆
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T64244CDK4/6-IN-10;化合物 CDK4/6-IN-10CDK4/6-IN-10
CDK4/6-IN-10 is a selective, potent, orally active inhibitor of CDK4 (IC50: 22 nM) and CDK6 (IC50: 10 nM) with antitumour effects. CDK4/6-IN-10 has potential for studies in multiple myeloma (MM).
价 格:¥电议型 号:T64244产 地:中国大陆
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T64242CCR1 antagonist 11 hydrochloride;化合物 CCR1 antagonist 11 hydrochlorideCCR1 antagonist 11 hydrochlorid
CCR1 antagonist 11 hydrochloride (A1B1) is an orally active CCR1 antagonist that acts on hCCR1 (IC50: 0/.03 μM), mCCR1 (IC50: 0.58 μM), rCCR1 (IC50: 0.32 μM). 11 hydrochloride can be used to study rheumatoid arthritis and other related inflammatory diseases.
价 格:¥电议型 号:T64242产 地:中国大陆
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T64241Brinzolamide hydrochloride;化合物 Brinzolamide hydrochlorideBrinzolamide hydrochloride
Brinzolamide (AL-4862) hydrochloride is a selective inhibitor (IC50: 3.2 nM) of carbonic anhydrase II. Brinzolamide hydrochloride inhibits ciliary CA-II and reduces atrial fluid secretion, thereby reducing intraocular pressure (IOP). Brinzolamide hydrochloride can be used to study glaucoma disease.
价 格:¥电议型 号:T64241产 地:中国大陆
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T6424Bromfenac Sodium;溴芬酸钠AHR 10282B|||Bronuck|||AHR 10282R;AHR 10282B|||Bronuck|||AHR 10282R|||溴芬酸钠
Bromfenac Sodium (AHR 10282R) is a nonsteroidal anti-inflammatory drug (NSAID), which has anti-inflammatory activity and may block prostaglandin synthesis by inhibiting cyclooxygenase 1 and 2.
价 格:¥电议型 号:T6424产 地:中国大陆
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T64239Belatacept;化合物 BelataceptBelatacept
Belatacept (BMS 224818) is a selective blocker of T-cell costimulation. Belatacept binds CD 80/86 ligands and thus exhibits an inhibitory effect on CD-28-mediated T-cell costimulation. Belatacept can be used to study organ transplantation immunosuppression.
价 格:¥电议型 号:T64239产 地:中国大陆