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T35900JAK2-IN-7;化合物JAK2-IN-7JAK2-IN-7;JAK2-IN-7
JAK2-IN-7, a selective inhibitor targeting Janus Kinase 2 (JAK2), exhibits inhibitory concentrations (IC50) of 3 nM for JAK2, 11.7 nM for SET-2 cells, and 41 nM for Ba/F3 V617F cells, indicative of its potency and selectivity. This compound demonstrates more than 14-fold selectivity against JAK1, JAK3, and FLT3, underlining its specificity. JAK2-IN-7 effectively induces cell cycle arrest at the G0/G1 phase and promotes apoptosis in tumor cells, manifesting significant antitumor activities [1].
价 格:¥电议型 号:T35900产 地:中国大陆
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T35829CC-90005;CC-90005CC-90005
CC-90005 is a potent, selective and orally active inhibitor of protein kinase C-θ (PKC-θ), with an IC50 of 8 nM. CC-90005 shows selectivity for PKC-θ over PKC-δ (IC50=4440 nM). CC-90005 can inhibit T cell activation by IL-2 expression[1].
价 格:¥电议型 号:T35829产 地:中国大陆
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T35740FR900098 (sodium salt)FR900098 (sodium salt)FR900098 (sodium salt)|||FR-900098 (sodium salt)
FR900098 is a derivative of fosmidomycin that has antimalarial activity (IC50s = 170, 170, and 90 nM for HB3, A2, and Dd2 P. falciparum strains, respectively). FR900098 inhibits DOXP reductoisomerase, a key enzyme in the non-mevalonate pathway of isoprenoid biosynthesis, in vitro in a dose-dependent manner. FR900098 (>10 mg/kg, i.p.) eradicated P. vinckei parasites within four days in mice.
价 格:¥电议型 号:T35740产 地:中国大陆
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T34900Tolypomycin R;化合物 T34900B-2847-R;B-2847-R
Tolypomycin R is a rifamycin derivative.
价 格:¥电议型 号:T34900产 地:中国大陆
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T34573SCH-900271;化合物SCH-900271SCH 900271;SCH 900271
SCH-900271 is a potent nicotinic acid receptor for the treatment of dyslipidaemia and is commonly used in the study of mixed hyperlipidaemia and primary hypercholesterolaemia.
价 格:¥电议型 号:T34573产 地:中国大陆
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T3454VER-49009;化合物VER-49009CCT 129397;CCT 129397
VER-49009 (CCT 129397) is a potent Hsp90 inhibitor(IC50 of 25 nM and Kd of 78 nM).
价 格:¥电议型 号:T3454产 地:中国大陆
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T33900PD 160336;化合物 T33900PD160336|||PD-160336;PD160336|||PD-160336
PD 160336 is a biochemical.
价 格:¥电议型 号:T33900产 地:中国大陆
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T33757NSC659000;化合物 T33757NSC-659000|||NSC 659000;NSC-659000|||NSC 659000
NSC659000 is a potential antifungal drug.
价 格:¥电议型 号:T33757产 地:中国大陆
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T32900Saccharopine;化合物 T32900L-Saccharopine|||accharopin;L-Saccharopine|||accharopin
L-Saccharopine is a product of the breakdown of essential amino acid Lysine.
价 格:¥电议型 号:T32900产 地:中国大陆
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T32607Lavendomycin;化合物 T32607Antibiotic FR 900201|||FR-900201|||FR 900201|||FR900201;Antibiotic FR 900201|
Lavendomycin can be extracted from Streptomyces lavendulae and has active against Gram-positive bacteria.
价 格:¥电议型 号:T32607产 地:中国大陆
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T32464L 685487;化合物 T3246413-Desmethyl FR 900520|||L685487|||L-685487;13-Desmethyl FR 900520|||L685487|||L-
L 685487 is produced by microbial transformation of FR 900520.
价 格:¥电议型 号:T32464产 地:中国大陆
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T31908gamma-tert-Butyl methotrexate;化合物 T31908gamma-Tbmtx|||NSC378900|||NSC-378900|||NSC 378900;gamma-Tbmt
gamma-tert-Butyl methotrexate is a bioactive chemical.
价 格:¥电议型 号:T31908产 地:中国大陆
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T31900GA3-AM;化合物 T31900GA3-AM
GA3-AM is a cell permeable chemical dimerizer.
价 格:¥电议型 号:T31900产 地:中国大陆
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T31725Etozolin;化合物 T31725GO 687|||W-2900A|||W2900A|||GO-687|||W 2900A;GO 687|||W-2900A|||W2900A|||GO-687||
Ezozolin (Diulozin, W-2900A) is a diuretic used for the treatment of edema and hypertension.
价 格:¥电议型 号:T31725产 地:中国大陆
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T30964Clamoxyquin hydrochloride;化合物 T30964Clamoxyquin HCl|||Clamoxyquin dihydrochloride|||CN-17,900-2B|||C
Clamoxyquin hydrochloride is an anti ameba and antidiarrheal drug. It has been used as a veterinary drug to treat salmon infected with brain armyworm.
价 格:¥电议型 号:T30964产 地:中国大陆
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T30900Chlorphenoctium amsonate;化合物 T30900Chlorphenoctium amsonate
Chlorphenoctium amsonate is a biochemical.
价 格:¥电议型 号:T30900产 地:中国大陆
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T30760CB 30900;化合物 T30760CB30900|||CB-30900;CB30900|||CB-30900
CB30900 is a novel and effective thymidylate synthase inhibitor.
价 格:¥电议型 号:T30760产 地:中国大陆
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T30640Butyrylcholine;化合物 T30640BA 51 090059|||BA-51-090059|||BA 51090059|||BA 51-090059;BA 51 090059|||BA-
Butyrylcholine is a novel colonic ion transport regulator produced by colonic epithelial cells that stimulates nicotine and muscarinic receptors.
价 格:¥电议型 号:T30640产 地:中国大陆
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T30516BMS-347070;化合物 T30516SCHEMBL6882900|||BMS 347070|||0CKM4H090C|||UNII-0CKM4H090C;SCHEMBL6882900|||BMS
BMS-347070 is a COX-2 inhibitor.
价 格:¥电议型 号:T30516产 地:中国大陆
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T30498BMS-187308;化合物 T30498BMS187308|||UNII-7K0YU35900|||BMS 187308;BMS187308|||UNII-7K0YU35900|||BMS 1873
BMS-187308 is an endothelin-A (ETA) selective antagonist.
价 格:¥电议型 号:T30498产 地:中国大陆