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产品数:86101
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TN1362AfzelinPTEN,MMAC1,Afzelin,Phosphatase and tensin homolog,inhibit,Autophagy,Inhibitor,Bacterial,Mitoc
Afzelin has several cellular activities such as DNA-protective, antibacterial, antioxidant, and anti-inflammatory as well as UV-absorbing activity and may protect human skin from UVB-induced damage by a combination of UV-absorbing and cellular activities. Afzelin attenuates the mitochondrial damage, enhances mitochondrial biogenesis and decreases the level of mitophagy-related proteins, parkin and PTEN-induced putative kinase 1.
价 格:¥电议型 号:TN1362产 地:中国大陆
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TP1328TB500cell differentiation,keratinocyte migration,TB500,collagen deposition,TB 500,TB-500,thymosin β
TB-500 is a synthesised peptide, essentially a short-chain version of the naturally occurring Thymosin Beta-4.
价 格:¥电议型 号:TP1328产 地:中国大陆
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T6S1665IrisflorentinNOS,Irisflorentin,inhibit,Inhibitor,iNOS,Nitric oxide synthases,macrophages,inflammator
1. Irisflorentin blocks apoptosis pathways, by exerting its effects by promoting rpn-3 expression to enhance the activity of proteasomes and down-regulating egl-1 expression. 2. Irisflorentin has anti-inflammatory mechanism in LPS-activated RAW 264.7 macrophages, by reducing the transcriptional and translational levels of inducible nitric oxide synthase (iNOS) as well as the production of NO.
价 格:¥电议型 号:T6S1665产 地:中国大陆
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T125975-HT2 antagonist 15HT2 antagonist 1,5 HT2 antagonist 1,5-HT-2 antagonist 1
5-HT2 antagonist 1 is a potent 5-HT2 receptor antagonist, has weak α1 adrenoceptor blocking activity.
价 格:¥电议型 号:T12597产 地:中国大陆
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T7493AG-13958Vascular endothelial growth factor receptor,AG 013958,AG 13958,inhibit,VEGFR,AG13958,AG-1395
AG-13958 (AG-013958), a potent VEGFR tyrosine kinase inhibitor, for the treatment of age-related macular degeneration.
价 格:¥电议型 号:T7493产 地:中国大陆
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T39762AHR antagonist 5 free baseAHR antagonist 5 free base
AHR antagonist 5 free base is an orally active antagonist of AHR with IC50s of ~35-150 nM in human and rodent cell lines.
价 格:¥电议型 号:T39762产 地:中国大陆
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T6510GDC-0349Mammalian target of Rapamycin,GDC0349,GDC 0349,mTOR,inhibit,Autophagy,GDC-0349,Inhibitor
GDC-0349 is a potent and selective ATP-competitive inhibitor of mTOR with Ki of 3.8 nM, 790-fold inhibitory effect against PI3Kα and other 266 kinases. Phase 1.
价 格:¥电议型 号:T6510产 地:中国大陆
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TQ0239PF-06291874inhibit,Inhibitor,glucagon,bioavailability,Glucagon Receptor,PF 06291874,Glucagon recepto
PF-06291874 (Glucagon receptor antagonists-4) is a highly effective and orally active antagonist of the glucagon receptor.
价 格:¥电议型 号:TQ0239产 地:中国大陆
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T6954PRIMA-1NSC 281668,PRIMA1,Autophagy,Apoptosis,PRIMA-1,inhibit,NSC281668,MDM-2/p53,Ferroptosis,Inhibit
PRIMA-1 is a mutant p53 reactivator. It induces apoptosis and inhibits growth of human tumors with mutant p53.
价 格:¥电议型 号:T6954产 地:中国大陆
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T9902AtezolizumabAtezolizumab,Inhibitor,MPDL3280A,inhibit,Apoptosis,Autophagy
Atezolizumab anti-PD-L1) is a fully humanized IgG1 monoclonal antibody that blocks the interaction of PD-L1 with both PD-1 and B7.1 but not the interaction of PD-L2 with PD-1.
价 格:¥电议型 号:T9902产 地:中国大陆
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T8198VisnaginCYP1A1,inhibit,HepG2,vascular,acute,vasodilator,Visnagin,muscles,Inhibitor,pancreatitis,smoo
Visnagin has acute hypotensive, anti-inflammatory, and neuroprotective effects, it protects against doxorubicin-induced cardiomyopathy through modulation of mitochondrial malate dehydrogenase.
价 格:¥电议型 号:T8198产 地:中国大陆
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T6797TelaglenastatGlutaminase,antiproliferative,HCC-1806,TNBC,Telaglenastat,breast,Inhibitor,Autophagy,sp
CB-839(IC50 of 24 nM), an effective, specific, and oral inhibitor, which is bioavailable glutaminase, for recombinant human GAC.
价 格:¥电议型 号:T6797产 地:中国大陆
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T7894Tazarotenic acidretinoid action,inhibit,retinoic acid receptor,AGN190299,Drug Metabolite,warty dyske
AGN-190299 is a retinoid prodrug which is converted to its active form
价 格:¥电议型 号:T7894产 地:中国大陆
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T7190ActeinJNK,Akt,Actein,Apoptosis,PKB,Autophagy,Inhibitor,inhibit,Protein kinase B
Actein has a stimulatory effect on osteoblastic bone formation or has potential activity against osteoporosis, it also can prevent oxidative damage to osteoblasts in osteoporotic patients. Actein´s ability to pathways involved in lipid disorders and carcinogenesis may make it a new agent for preventing and treating these major disorders, it has been shown to inhibit the proliferation of human breast cancer cells, by altering the activity of the ER IP3 receptor and Na,K-ATPase, inducing cal
价 格:¥电议型 号:T7190产 地:中国大陆
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T2454DacinostatLAQ-824,Dacinostat,Histone deacetylases,inhibit,Autophagy,HDAC,Inhibitor,LAQ 824
LAQ824 (Dacinostat) is a novel HDAC inhibitor with IC50 of 32 nM and is an activator of the p21 promoter.
价 格:¥电议型 号:T2454产 地:中国大陆
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T8820BML-284 hydrochlorideBML284 hydrochloride,AGS,TCF,N-cadherin,Wnt,BML284,cardiac defect,MNK45,BML 284
BML-284 HCL is a potent, selective Wnt canonical signaling activator and tubulin polymerization inhibitor.
价 格:¥电议型 号:T8820产 地:中国大陆
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T7144BTSfibers,muscle,Myosin,subfragment,inhibit,BTS,Inhibitor,skeletal,Ca2+,actin,ATPase
BTS is a potent inhibitor of Ca2+-stimulated myosin S1 ATPase (IC50 : 5 μM) .
价 格:¥电议型 号:T7144产 地:中国大陆
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T7799BMP signaling agonist sb4Inhibitor,SMAD,bmp,cell,inhibit,BMP signaling agonist sb4,BRE-luc,BMP signa
SB 4 is an agonist of benzoxazole bone morphogenetic protein (BMP) signaling (EC50 :74 nM)
价 格:¥电议型 号:T7799产 地:中国大陆
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T6798TretazicarTretazicar,NQO1,DNA Alkylator/Crosslinker,rat,bifunctional,Inhibitor,inhibit,agent,cross-l
CB1954(Tretazicar), an anticancer prodrug, is activated by NAD(P)H quinone oxidoreductase 2. It is converted in the presence of the enzyme NQO2 and co-substrate caricotamide ( EP-0152R) (EP) into a potent cytotoxic bifunctional alkylating agent.
价 格:¥电议型 号:T6798产 地:中国大陆