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T8542BMS-345541 hydrochloride化合物BMS-345541 hydrochlorideN-(1,8-二甲基咪唑并[1,2-A]喹喔啉-4-基)-1,2-乙二胺盐酸盐
BMS-345541 hydrochloride is a selective IKK inhibitor (IKK2 and IKK1 with IC50 of 0.3 μM and 4 μM,respectively).
价 格:¥电议型 号:T8542产 地:中国大陆
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T8470BMS-1001;化合物BMS-1001BMS-1001
BMS-1001 is a potent inhibitor of PD-1/PD-L1 interaction(IC50 : 2.25 nM, in a homogenous time-resolved fluorescence binding assay).
价 格:¥电议型 号:T8470产 地:中国大陆
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T84297BMS-986365;化合物 BMS-986365BMS-986365
BMS-986365 is a ligand-directed androgen receptor degrader (AR LDD) that inhibits androgen-stimulated transcription of AR target genes and can be used to study prostate cancer.
价 格:¥电议型 号:T84297产 地:中国大陆
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T839096-hydroxy Buspirone;化合物 6-hydroxy BuspironeBMY 28674|||BMS-52821;BMY 28674|||BMS-52821
6-Hydroxy Buspirone, an active metabolite of the anxiolytic compound buspirone, is produced via the cytochrome P450 (CYP) isoform CYP3A4. This compound exhibits affinity for the serotonin (5-HT) receptor subtype 5-HT1A, demonstrating efficacy in the rat hippocampus and dorsal raphe with half-maximal effective concentrations (EC50s) of 4 and 1 ?M, respectively. Furthermore, 6-Hydroxy Buspirone acts as a potent antagonist against dopamine D2, D3, and D4 receptors with half-maximal inhibitory conce
价 格:¥电议型 号:T83909产 地:中国大陆
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T8384Gatifloxacin hydrochloride;加替沙星盐酸盐AM-1155 (hydrochloride)|||BMS-206584 (hydrochloride)|||PD135432 (h
Gatifloxacin hydrochloride (AM-1155 hydrochloride) is an antibiotic of the fourth-generation fluoroquinolone family, which can inhibit the bacterial enzyme DNA rotase and topoisomerase IV.
价 格:¥电议型 号:T8384产 地:中国大陆
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T8326BMS-2化合物BMS-21-(4-氟苯基)-N-[3-氟-4-(1H-吡咯并[2,3-B]吡啶-4-基氧基)苯基]-1,2-二氢-2-氧代-3-吡啶甲酰胺
BMS-2 is a Met/Flt-3/VEGFR2 tyrosine kinase inhibitor.
价 格:¥电议型 号:T8326产 地:中国大陆
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T82994Anzurstobart;化合物 AnzurstobartBMS-986351|||CC-95251;BMS-986351|||CC-95251
Anzurstobart (CC-95251; BMS-986351), a fully human monoclonal anti-SIRPα antibody with high affinity, inhibits CD47-SIRPα interaction. It potentiates macrophage-mediated phagocytosis of DLBCL cell lines in co-culture assays with Rituximab and shows promise in solid and hematologic malignancy research [1].
价 格:¥电议型 号:T82994产 地:中国大陆
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T82850BMS-332;化合物 BMS-332BMS-332
BMS-332 is a dual inhibitor of the lipid kinases DGKα and DGKζ, demonstrating half-maximal inhibitory concentrations (IC50) of 0.005 μM for DGKα and 0.001 μM for DGKζ [1].
价 格:¥电议型 号:T82850产 地:中国大陆
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T82849BMS-496;化合物 BMS-496BMS-496
BMS-496 is a dual DGKα/ζ lipid kinase inhibitor exhibiting IC50 values of 0.09 μM (DGKα) and 0.006 μM (DGKζ) [1].
价 格:¥电议型 号:T82849产 地:中国大陆
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T82848BMS-986172;化合物 BMS-986172BMS-986172
BMS-986172 is an orally active, highly selective inhibitor of MGAT2, demonstrating inhibitory concentrations (IC50) of 4.6 nM for human MGAT2 (hMGAT2) and 20 nM for mouse MGAT2 (mMGAT2). It exhibits a half-life (T1/2) greater than 120 minutes in vitro and is known to decrease food intake and body weight. This compound is considered promising for the research of metabolic disorders, including obesity and non-alcoholic steatohepatitis (NASH) [1].
价 格:¥电议型 号:T82848产 地:中国大陆
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T80600Peginterferon lambda-1a;化合物 Peginterferon lambda-1aBMS-914143;BMS-914143
Peginterferon lambda-1a (BMS-914143) is a monoclonal antibody that targets IFNLR1 and is composed of IFNL1 conjugated to pegol [1].
价 格:¥电议型 号:T80600产 地:中国大陆
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T78659Crexavibart;化合物 CrexavibartBMS-986413|||C-144-LS;BMS-986413|||C-144-LS
Crexavibart (BMS-986413; C-144-LS), an IgG1 λ2 antibody, specifically targets the receptor-binding domain of the SARS-CoV-2 spike (S) glycoprotein [1].
价 格:¥电议型 号:T78659产 地:中国大陆
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T7804LGarenoxacin mesylate;化合物 T7804LGarenoxacin mesilate|||BMS 284756|||BM-284756|||BMS284756;Garenoxacin
Garenoxacin mesylate, a novel oral des-fluoro quinolone, has potent antimicrobial activity against common respiratory pathogens, including resistant strains and Gram-negative and Gram-positive bacterial infections.
价 格:¥电议型 号:T7804L产 地:中国大陆
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T7804Garenoxacin mesylate hydrate;加雷沙星甲磺酸盐Garenoxacin mesylate [USAN]|||BMS284756 (Mesylate hydrate);Gare
Garenoxacin mesylate hydrate (Garenoxacin mesylate [USAN]) with potent antimicrobial activity, against common respiratory pathogens, including resistant strains.
价 格:¥电议型 号:T7804产 地:中国大陆
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T7787BMS817378化合物BMS817378[3-[[4-((2-氨基-3-氯吡啶-4-基)氧基)-3-氟苯基]氨基甲酰基]-5-(4-氟苯基)-4-氧代-4H-吡啶-1-基]甲基磷酸二氢酯
BMS817378 is a potent and selective inhibitor of MET(IC50 : 1.7 nM).
价 格:¥电议型 号:T7787产 地:中国大陆
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T77761BMS-502;化合物 BMS-502BMS-502
BMS-502 is a potent dual inhibitor of diacylglycerol kinase (DGK) α and ζ that induces immune responses in human and mouse T cells and blocks intracellular checkpoint signaling in T cells. BMS-502 stimulates immune responses in a dose-dependent manner and can be used to study immune-related diseases.
价 格:¥电议型 号:T77761产 地:中国大陆
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T77760BMS-684;化合物BMS-684BMS-684
BMS-684 is a selective and potent DGKα inhibitor (IC50: 15 nM) with potential antitumor activity.BMS-684 inhibits DGKα kinase, DGKβ, and DGKγ.BMS-684 activates T-cells, which may prevent and treat immune-related diseases.
价 格:¥电议型 号:T77760产 地:中国大陆
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T77367Urelumab;乌瑞芦单抗BMS-663513|||BMS-66513;BMS-663513|||BMS-66513
Urelumab(BMS-66513) is a humanized IgG4 monoclonal antibody, often used as a CD137 agonist.Urelumab has potential antitumor activity, potentiating tumor cell killing by T-cells and natural killer cells, and enhancing the cytotoxicity of Rituximab.Urelumab has been used in the study of solid tumor-related diseases such as diffuse large B-cell lymphoma (DLBCL) and follicular lymphoma (FL). Urelumab can be used to study diseases associated with solid tumors such as diffuse large B-cell lymphoma (DL
价 格:¥电议型 号:T77367产 地:中国大陆
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T76830Teneliximab;化合物TeneliximabChi220|||Anti-Human CD40 Recombinant Antibody|||BMS 224819;Chi220|||Anti-H
Teneliximab (Chi220) is a chimeric monoclonal antibody and a tumor necrosis factor receptor superfamily member 5 (CD40) inhibitor that blocks CD40-CD40L interactions.Teneliximab exerts partial agonist activity through CD40 and peripheral B-cell depletion, and may be used to study organ transplant rejection and rheumatoid arthritis.
价 格:¥电议型 号:T76830产 地:中国大陆
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T76794Ulocuplumab;乌洛鲁单抗BMS 936564|||MDX 1338;BMS 936564|||MDX 1338
Ulocuplumab (BMS-936564) is a fully human anti-CXCR4 IgG4 antibody.Ulocplumab exhibits antitumor activity in acute myeloid leukemia (AML), non-Hodgkin´s lymphoma (NHL), and multiple myeloma transplantation models.Ulocplumab inhibits the migration of chronic lymphocytic leukemia (CLL) cells under CXCR4 activation, induces apoptosis, and inhibits the growth and migration of cancer cells. Ulocplumab inhibits CXCL12-mediated chronic lymphocytic leukemia (CLL) cell migration in response to CXCR
价 格:¥电议型 号:T76794产 地:中国大陆