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T62356Mardepodect hydrochloride;Mardepodect 盐酸盐PF-2545920 HCl|||Mardepodect HCl|||MP-10 HCl|||PF-02545920
Mardepodect hydrochloride (Mardepodect HCl) is an orally active, selective and potent inhibitor of PDE10A that crosses the blood-brain barrier (IC50: 0.37 nM).Mardepodect hydrochloride up-regulates the expression of proteins encoding specific growth and transcription factors, cell signalling molecules and cell surface proteins. Mardepodect hydrochloride upregulates genes encoding specific growth factors, transcription factors, cell signalling molecules, and cell surface proteins, while downregul
价 格:¥电议型 号:T62356产 地:中国大陆
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T6121Tepotinib;特泊替尼EMD-1214063|||MSC2156119;特泊替尼|||EMD-1214063|||MSC2156119
Tepotinib (EMD-1214063) is an inhibitor of MET tyrosine kinase with potential antineoplastic activity.
价 格:¥电议型 号:T6121产 地:中国大陆
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T6075Epothilone B;帕妥匹隆Patupilone|||EPO 906;帕妥匹隆|||Patupilone|||EPO 906
Epothilone B (EPO 906) is a compound isolated from the myxobacterium Sorangium cellulosum. Similar to paclitaxel, patupilone induces microtubule polymerization and stabilizes microtubules against depolymerization conditions. In addition to promoting tubulin polymerization and stabilization of microtubules, this agent is cytotoxic for cells overexpressing P-glycoprotein, a characteristic that distinguishes it from the taxanes. Patupilone may cause complete cell-cycle arrest.
价 格:¥电议型 号:T6075产 地:中国大陆
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T6042[11C]MP 10;化合物PF-2545920Mardepodect|||PF-2545920;Mardepodect|||PF-2545920
[11C]MP 10 (PF-2545920), a specific and effective PDE10A inhibitor (IC50=0.37 nM), is with more than1000-fold specificity activity over the PDE.
价 格:¥电议型 号:T6042产 地:中国大陆
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T60263Povafonidine;化合物 PovafonidinePovafonidine
Povafonidine (PGE-6201204) is a potent alpha-2 adrenoreceptor agonist. Povafonidine can constrict blood vessels and reduce mucosal congestion which can be used for nasal congestion research [1].
价 格:¥电议型 号:T60263产 地:中国大陆
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T5333Rimeporide hydrochloride;盐酸RimeporideEMD-87580 hydrochloride;盐酸Rimeporide|||EMD-87580 hydrochloride
Rimeporide hydrochloride (EMD-87580 hydrochloride) is a potent and selective Sodium hydrogen exchange 1 (NHE-1) inhibitor.
价 格:¥电议型 号:T5333产 地:中国大陆
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T5319Rimeporide;化合物RimeporideEMD-87580;EMD-87580
Rimeporide (EMD-87580) (EMD-87580) is a potent and selective Sodium hydrogen exchange 1 (NHE-1) inhibitor.
价 格:¥电议型 号:T5319产 地:中国大陆
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T4S1999Valepotriate;戊曲酯/缬草素Valtrate;戊曲酯/缬草素|||Valtrate
Valepotriate (Valtrate) fraction can have sedative effects and affect behavioral parameters related to recognition memory. Valepotriates, a new class of cytotoxic and antitumor agents, they are very potent cytotoxic agents for the HTC hepatoma cells. Valepotriates may have a potential anxiolytic effect on the psychic symptoms of anxiety.
价 格:¥电议型 号:T4S1999产 地:中国大陆
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T4567Sulfaphenazole磺胺苯吡唑Plisulfan|||Raziosulfa|||Depocid|||磺胺苯吡唑|||Depotsulfonamide
Sulfaphenazole (Plisulfan) is an inhibitor of CYP2C9 (Ki: 0.3 μM) that demonstrates at least 100-fold selectivity over other CYP450 isoforms (Ki: 63/29 μM for CYP2C8/CYP2C18, respectively, and no activity at CYP1A1, CYP1A2, CYP3A4, CYP2C19). At 10 μM, sulfaphenazole has been shown to inhibit endothelium-derived hyperpolarizing factor synthase, a CYP450 isozyme in the porcine coronary artery homologous to CYP2C8/9 that generates reactive oxygen species in coronary endothelial cells and modulates
价 格:¥电议型 号:T4567产 地:中国大陆
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T4501Ceftizoxime头孢唑肟头孢唑肟|||Epocelin
Ceftizoxime (Epocelin) is a cephalosporin-based, potent antibacterial agent which can be administered intravenously or by suppository. It is highly resistant to a broad spectrum of beta-lactamases and is active against a wide range of both aerobic and anaerobic gram-positive and gram-negative organisms.
价 格:¥电议型 号:T4501产 地:中国大陆
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T4374Edoxudine;乙去氧尿啶Aedurid|||EUDR|||Epoxudine;依度尿苷|||Aedurid|||EUDR|||Epoxudine|||乙去氧尿啶
Edoxudine (Epoxudine), an antiviral drug, is an analogue of thymidine and shows effectiveness against the herpes simplex virus. Edoxudine is used as a 5-fluorouracil (FU) modulator. Edoxudine may be used to enhance the therapeutic index of 5-FU by reducing the catabolism, prolonging the plasma and intratumoral concentrations of 5-FU, and offering protection to normal organs by increasing the endogenous uridine levels. It can also enhance the antitumour action of 5-FU.
价 格:¥电议型 号:T4374产 地:中国大陆
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T4071Repotrectinib;化合物TPX0005TPX-0005|||TPX 0005|||TPX0005;TPX-0005|||TPX 0005|||TPX0005
Repotrectinib (TPX-0005) is a potent ALK/ROS1/TRK inhibitor, with IC50 of 1.01 nM, 5.3 nM, 1.08 nM and 1.26 nM for WT ALK, SRC, ALK L1196M and ALK G1202R, respectively.
价 格:¥电议型 号:T4071产 地:中国大陆
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T40174PolyvinylimidazolePolyvinylimidazoleVimdemer|||Polyvinylimidazole
Polyvinylimidazole (Vimdemer) is a weak basic polyelectrolyte commonly utilized as a model for studying adsorption properties on various minerals.
价 格:¥电议型 号:T40174产 地:中国大陆
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T40105Pomalidomide-PEG3-C2-NH2 hydrochloride;Pomalidomide-PEG3-C2-NH2 hydrochloridePomalidomide-PEG3-C2-NH
Pomalidomide-PEG3-C2-NH2 hydrochloride, also known as Cereblon Ligand-Linker Conjugate 5, is a chemically synthesized E3 ligase ligand-linker conjugate. This compound incorporates a cereblon ligand based on Pomalidomide and a linker commonly employed in PROTAC technology.
价 格:¥电议型 号:T40105产 地:中国大陆
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T40085Pomalidomide-amino-PEG5-NH2 hydrochloride;Pomalidomide-amino-PEG5-NH2 hydrochloridePomalidomide-amin
Pomalidomide-amino-PEG5-NH2 hydrochloride is a chemical compound that has been synthesized as an E3 ligase ligand-linker conjugate. This compound combines a Pomalidomide-based cereblon ligand with a linker commonly used in PROTAC technology.
价 格:¥电议型 号:T40085产 地:中国大陆
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T40015Pomalidomide-PEG2-NH2 hydrochloride;化合物Pomalidomide-PEG2-NH2 hydrochloridePomalidomide-PEG2-NH2 hydr
Pomalidomide-PEG2-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based CRBN ligand and linker used in PROTAC technology.
价 格:¥电议型 号:T40015产 地:中国大陆
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T40004Pomalidomide-C7-NH2 hydrochloride;化合物Pomalidomide-C7-NH2 hydrochloridePomalidomide-C7-NH2 hydrochlor
Pomalidomide-C7-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based CRBN ligand and linker used in PROTAC technology.
价 格:¥电议型 号:T40004产 地:中国大陆
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T40002Pomalidomide-C3-NH2 hydrochloride;化合物Pomalidomide-C3-NH2 hydrochloridePomalidomide-C3-NH2 hydrochlor
Pomalidomide-C3-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based CRBN ligand and linker used in PROTAC technology.
价 格:¥电议型 号:T40002产 地:中国大陆
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T3S2016Epoxylathyrol;环氧续随子醇Epoxylathyrol
Epoxylathyrol derivatives have modulation of ABCB1-mediated multidrug resistance in human colon adenocarcinoma and mouse T-Lymphoma cells.
价 格:¥电议型 号:T3S2016产 地:中国大陆
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T39953Pomalidomide-amino-PEG3-NH2 hydrochloride;Pomalidomide-amino-PEG3-NH2 hydrochloridePomalidomide-amin
Pomalidomide-amino-PEG3-NH2 hydrochloride is a synthetic conjugate compound incorporating the cereblon ligand from Pomalidomide and a linker commonly utilized in PROTAC technology. This compound functions as an E3 ligase ligand-linker conjugate in biochemical reactions.
价 格:¥电议型 号:T39953产 地:中国大陆