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T2162Maribavir;马立巴韦BW1263W94|||GW257406X|||Benzimidavir|||1263W94;BW1263W94|||GW257406X|||Benzimidavir|||
Maribavir (GW257406X) is an orally available benzimidazole riboside compound with activity against cytomegalovirus (CMV). Maribavir is a selective ATP competitor of the viral UL97 kinase, which is involved in viral nuclear maturation events, such as viral DNA assembly and movement of viral capsids from the nucleus of infected cells. Maribavir has activity against strains of CMV that are resistant to standard anti-CMV agents.
价 格:¥电议型 号:T2162产 地:中国大陆
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T2020RGW 611;化合物RGW 611RGW 611
RGW 611 is a morpholine derivative that enhances radiation and induces cell death in hypoxic V79-379A cells.
价 格:¥电议型 号:T2020产 地:中国大陆
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T1978GW627368;化合物GW 627368XGW 627368X;GW 627368X
GW627368 (GW 627368X)X is a novel, potent and selective antagonist of prostanoid EP4 receptor.
价 格:¥电议型 号:T1978产 地:中国大陆
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T1800GW788388;化合物GW 788388GW 788388;GW 788388
GW788388 is a potent and selective inhibitor of ALK5, also inhibits TGF-(beta) type II receptor and activin type II receptor activities.
价 格:¥电议型 号:T1800产 地:中国大陆
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T1781GW9508;化合物GW 9508GW 9508;GW 9508
GW9508(GW 9508) is a potent and selective agonist for FFA1 (GPR40), stimulates insulin secretion in a glucose-sensitive manner.
价 格:¥电议型 号:T1781产 地:中国大陆
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T16406Orvepitant maleate;化合物 T16406GW823296 maleate;GW823296 maleate
Orvepitant maleate is an effective, selective, and well-tolerated neurokinin-1 receptor (NK-1) antagonist (pKi: 10.2 for human neurokinin-1 receptor). Orvepitant maleate has the potential for depressive disorder and chronic refractory cough (CRC) treatment. Orvepitant maleate can across the blood-brain barrier.
价 格:¥电议型 号:T16406产 地:中国大陆
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T15689L-798106化合物 T15689CM9|||GW671021
L-798106 is a highly selective prostanoid EP3 receptor antagonist (Ki=0.3 nM). It also has micromolar activities at EP4, EP1, and EP2 receptors (Ki: 916 nM, >5000 nM, and >5000 nM at EP4, EP1, and EP2, respectively).
价 格:¥电议型 号:T15689产 地:中国大陆
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T15454GW843682X;化合物GW843682XGW843682;GW843682
GW843682X (GW843682) is a selective and ATP-competitive inhibitor of PLK1 and PLK3 (IC50s = 2.2 nM and 9.1 nM).
价 格:¥电议型 号:T15454产 地:中国大陆
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T15453GW7647化合物GW76472-[[4-[2-[[环己基氨基)羰基](4-环己基丁基)氨基]乙基]苯基]硫基]-2-甲基丙酸
GW7647 is a potent agonist of PPARα (EC50s: 6 nM, 1.1 μM, and 6.2 μM for human PPARα, PPARγ, and PPARδ, respectively).
价 格:¥电议型 号:T15453产 地:中国大陆
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T15452GW7604;化合物 T15452GW7604
GW7604 is an antiestrogen and it also is the metabolite of GW5638. GW5638 is an antagonist of high-affinity estrogen receptor (ER).
价 格:¥电议型 号:T15452产 地:中国大陆
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T15451GW-870086;化合物GW-870086GW-870086
GW-870086 is an effective anti-inflammatory agent. GW-870086 also plays a role in a glucocorticoid receptor agonist (pIC50: 10.1 in A549 cells expressing NF-κB).
价 格:¥电议型 号:T15451产 地:中国大陆
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T15450GW-803430;化合物 T15450GW-3430;GW-3430
GW-803430 is a potent and selective antagonist of melanin-concentrating hormone receptor 1 (MCH R1) (pIC50: 9.3). GW-803430 is orally active in an animal model of obesity.
价 格:¥电议型 号:T15450产 地:中国大陆
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T15449GW-406381化合物 T15449GW406381|||GW 406381
GW406381 is a highly selective inhibitor of cyclooxygenase-2 (COX-2). GW406381 also attenuates spontaneous ectopic discharge in the sural nerves of rats following chronic constriction injury.
价 格:¥电议型 号:T15449产 地:中国大陆
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T15448GW-1100;化合物 T15448GW-1100
GW-1100 is a selective antagonist of GPR40 (pIC50: 6.9). GW1100 also plays the role of a GPR40 inverse agonist.
价 格:¥电议型 号:T15448产 地:中国大陆
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T15214Emicerfont;化合物 T15214GW876008;GW876008
Emicerfont is an antagonist of the corticotropin-releasing factor type 1 receptor (IC50: 66 nM).
价 格:¥电议型 号:T15214产 地:中国大陆
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T14307Aplaviroc;阿拉韦洛GSK 873140|||ONO-4128|||GW 873140|||AK 602;GSK 873140|||ONO-4128|||GW 873140|||AK 602
Aplaviroc (AK 602) is a novel and highly potent CCR5 antagonist with antiviral activity that inhibits HIV-1Ba-L, HIV-1JRFL, and HIV-1MOKW and can be used in the study of human immunodeficiency virus infection.
价 格:¥电议型 号:T14307产 地:中国大陆
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T12970LSolabegron HCl;化合物 T12970LGW-427,353|||GW427353|||GW-427353|||GW 427,353|||GW427,353;GW-427,353|||GW
Solabegron (GW-427,353), is a selective agonist of β3 adrenergic receptors. In addition, Solabegron has been shown to produce visceral analgesia by releasing somatostatin from fat cells.
价 格:¥电议型 号:T12970L产 地:中国大陆
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T12850Dilmapimod;度马莫得SB-681323|||GW 681323;SB-681323|||GW 681323|||度马莫得
Dilmapimod (SB-681323) is a potent inhibitor of p38 MAPK ,it potentially suppresses inflammation in chronic obstructive pulmonary disease.
价 格:¥电议型 号:T12850产 地:中国大陆
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T12720Prinoxodan化合物 T12720RGW2938
Prinoxodan is an inhibitor of phosphodiesterase.
价 格:¥电议型 号:T12720产 地:中国大陆
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T12565PRX933 hydrochloride;化合物PRX933盐酸盐BVT-933 hydrochloride|||GW876167 hydrochloride;BVT-933 hydrochlorid
PRX933 hydrochloride (GW876167 hydrochloride) is an agonist of 5-HT2C receptor and can be used in studies about hypertension acute treatment.
价 格:¥电议型 号:T12565产 地:中国大陆