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T61416Antileishmanial agent-9；化合物 Antileishmanial agent-9Antileishmanial agent-9
Antileishmanial agent-9 (compound 16c) exhibits potent and selective activity against Leishmania donovani (L. donovani) with an IC50 value of 4.01 μM. In addition, this compound demonstrates relatively low cytotoxicity in L-6 cells, with an IC50 value of 40.1 μM [1].
价 格：￥电议型 号：T61416产 地：中国大陆
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T61391Antileishmanial agent-3；化合物 Antileishmanial agent-3Antileishmanial agent-3
Antileishmanial agent-3 (Compound 13) effectively inhibits the growth of Leishmania major [1].
价 格：￥电议型 号：T61391产 地：中国大陆
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T61100Antileishmanial agent-4；化合物 Antileishmanial agent-4Antileishmanial agent-4
Antileishmanial agent-4, a ribonucleoside analogue, functions as an antileishmanial agent [1].
价 格：￥电议型 号：T61100产 地：中国大陆
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T61002hMAO-B-IN-3；化合物 hMAO-B-IN-3hMAO-B-IN-3
hMAO-B-IN-3 (Compound 15) is a potent hMAO-B inhibitor (IC 50 = 47.4 nM) with favourable drug-like properties and a broad safety window. Therefore, hMAO-B-IN-3 is a suitable candidate for lead optimization and multitarget-directed ligands development [1].
价 格：￥电议型 号：T61002产 地：中国大陆
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T60678hMAO-B-IN-2；化合物 hMAO-B-IN-2hMAO-B-IN-2
hMAO-B-IN-2 (compound 6j) is an orally active, potent, selective and BBB penetrated and competitive reversible inhibitor of hMAO-B (IC 50 = 4 nM) that can be used for the research of alzheimer’s disease. hMAO-B-IN-2 exhibits good neuroprotective effects and low toxicity in SH-SY5Y cell [1].
价 格：￥电议型 号：T60678产 地：中国大陆
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T60658hMAO-B/MB-COMT-IN-2；化合物 hMAO-B/MB-COMT-IN-2hMAO-B/MB-COMT-IN-2
hMAO-B/MB-COMT-IN-2 is a dual inhibitor of MAO-B/MB-COMT with IC 50s of 4.27 μΜ and 2.69 μΜ for hMAO-B and MB-COMT, respectively. hMAO-B/MB-COMT-IN-2 protects cells from oxidative damage that can be used in the neurodegeneration disease research, for example, Parkinson’s Disease (PD) [1].
价 格：￥电议型 号：T60658产 地：中国大陆
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T60638Antileishmanial agent-8；化合物 Antileishmanial agent-8Antileishmanial agent-8
Antileishmanial agent-8 (compound 18) shows potent and selective activity against Leishmania donovani ( L. donovani ) (IC50 = 5.64 μM) with relatively low cytotoxicity in L-6 cells (IC 50 =73.9 μM) [1].
价 格：￥电议型 号：T60638产 地：中国大陆
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T60489hMAO-B/MB-COMT-IN-1；化合物 hMAO-B/MB-COMT-IN-1hMAO-B/MB-COMT-IN-1
hMAO-B/MB-COMT-IN-1 is a dual MAO-B/MB-COMT inhibitor with IC50s of 2.5 μΜ for hMAO-B and 3.84 μΜ for MB-COMT. hMAO-B/MB-COMT-IN-1 protects cells from oxidative damage that can be used in neurodegeneration disease research, for example, Parkinson’s Disease (PD) [1].
价 格：￥电议型 号：T60489产 地：中国大陆
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T60395Nrf2-ARE/hMAO-B/QR2 modulator 1；化合物 Nrf2-ARE/hMAO-B/QR2 modulator 1Nrf2-ARE/hMAO-B/QR2 modulator 1
Nrf2-ARE/hMAO-B/QR2 modulator 1 is a new resveratrol-based multitarget-directed ligands (MTDLs) that showed a well-balanced MTDL profile: cellular activation of the NRF2-ARE pathway (CD = 9.83 μM), selective inhibition of both hMAO-B and QR2 (IC50s = 8.05 and 0.57 μM), and the best ability to promote hippocampal neurogenesis. Nrf2-ARE/hMAO-B/QR2 modulator 1 exerts neuroprotective and antioxidant actions in both acute and chronic Alzheimer models using hippocampal tissues.
价 格：￥电议型 号：T60395产 地：中国大陆
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T60196IHMT-PI3Kδ-372 S-isomer；化合物T60196IHMT-PI3Kδ-372 S-isomer
IHMT-PI3Kδ-372 S-isomer is a potent and selective PI3Kδ inhibitor with an IC50 of 14 nM. IHMT-PI3Kδ-372 S-isomer shows high selectivity over other class I PI3Ks (56?83 fold) and other protein kinases. IHMT-PI3Kδ-372 can be uesd for chronic obstructive pulmonary disease (COPD) research.
价 格：￥电议型 号：T60196产 地：中国大陆
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T4550Ajmaline阿义马林Cardiorythmine|||Raugalline|||阿义吗啉|||阿义马林|||Tachmalin|||(+)-Ajmaline
Ajmaline (Cardiorythmine) is a class Ia anti-arrhythmic compound that is widely used for the diagnosis of Brugada syndrome and the acute treatment of atrial or ventricular tachycardia. Ajmaline inhibits cardiac Kv1.5 and Kv4.3 channels at therapeutic concentrations.
价 格：￥电议型 号：T4550产 地：中国大陆
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T4543Telithromycin；泰利霉素HMR3647|||Ketek|||RU66647；HMR3647|||泰利霉素|||Ketek|||RU66647
Telithromycin (HMR3647) is a ketolide antibiotic to treat community acquired pneumonia of mild to moderate severity. Antibacterial Telithromycin prevents bacteria from growing, by interfering with their protein synthesis. Telithromycin binds to the subunit 50S of the bacterial ribosome, and blocks the progression of the growing polypeptide chain. Telithromycin has over 10 times higher affinity to the subunit 50S than erythromycin. In addition, telithromycin strongly bind simultaneously to two do
价 格：￥电议型 号：T4543产 地：中国大陆
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T4268CHMFL-BMX-078；化合物CHMFL-BMX-078CHMFL-BMX-078
CHMFL-BMX-078 is a highly potent and selective type II irreversible BMX kinase inhibitor with an IC50 of 11 nM.
价 格：￥电议型 号：T4268产 地：中国大陆
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T41291MS-PPOH；化合物MS-PPOHMS-PPOH
MS-PPOH is a potent and selective inhibitor of cytochrome P450 (CYP) epoxygenase. MS-PPOH inhibits CYP2C8 and CYP2C9 with IC50s of 15 and 11 ?M, respectively
价 格：￥电议型 号：T41291产 地：中国大陆
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T40384Mca-Ala-Pro-Lys(Dnp)-OH；Mca-Ala-Pro-Lys(Dnp)-OHMca-Ala-Pro-Lys(Dnp)-OH
Mca-Ala-Pro-Lys(Dnp)-OH, a specific quenched fluorogenic substrate for ACE2, enables the detection of ACE2 activity in various tissues including urinary, heart, and lung.
价 格：￥电议型 号：T40384产 地：中国大陆
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T40257Mc-Gly-Gly-Phe-Gly-PAB-OH；Mc-Gly-Gly-Phe-Gly-PAB-OHMc-GGFG-PAB-OH|||Mc-Gly-Gly-Phe-Gly-PAB-OH；Mc-GGF
Mc-Gly-Gly-Phe-Gly-PAB-OH, also known as Mc-GGFG-PAB-OH, serves as a cleavable ADC linker exclusively employed in the synthesis of antibody-drug conjugates (ADCs).
价 格：￥电议型 号：T40257产 地：中国大陆
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T4025HMN-154；化合物HMN154HMN154；HMN154
HMN-154 is a novel benzenesulfonamide anticancer compound. It is able to interact with NF-YB and interrupt the binding of NF-Y heterotrimer to DNA.
价 格：￥电议型 号：T4025产 地：中国大陆
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T40117Antileishmanial agent-1；Antileishmanial agent-1Antileishmanial agent-1
Antileishmanial agent-1 demonstrates activity against both L. amazonensis promastigotes (IC 50 = 15.52 μM) and intracellular amastigotes (IC 50 = 4.10 μM).
价 格：￥电议型 号：T40117产 地：中国大陆
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T40048MC-AAA-NHCH2OCH2COOH；MC-AAA-NHCH2OCH2COOHMC-AAA-NHCH2OCH2COOH；MC-AAA-NHCH2OCH2COOH
MC-AAA-NHCH2OCH2COOH (compound 20) is a cleavable antibody-drug conjugate (ADC) linker. Its primary application lies in the synthesis of ADCs.
价 格：￥电议型 号：T40048产 地：中国大陆
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T3S0462Rehmapicroside；地黄苦苷Rehmapicroside
Rehmapicroside is a natural product of Rehmannia, Scrophulariaceae. The catalog number is T3S0462 and the CAS number is 104056-82-8. Rehmapicroside can be used as a reference standard.
价 格：￥电议型 号：T3S0462产 地：中国大陆
