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  • T77697BML-278；化合物BML-278BML278|||BML 278；BML278|||BML 278

    BML-278 is a SIRT1 activator with an EC150 of 1 μM.BML-278 increases H3K9 methylation and inhibits H3K9 acetylation in parental and maternal prokaryotes, and can be used to improve early embryonic development.BML-278 induces cell cycle arrest in primary human mesenchymal stromal cells at the G1/S phase, and can be used to delay senescence.BML-278 reduces microtubule protein acetylation in U937 cells and increases mitochondrial density in mouse C2C12 myoblasts. BML-278 reduces microtubule protein

    价 格：￥电议型 号：T77697产 地：中国大陆

  • T755032-Hydroxyalbrassitriol；化合物 2-Hydroxyalbrassitriol2-Hydroxyalbrassitriol

    2-Hydroxyalbrassitriol (Compound 6) is an AChE inhibitor with an IC 50 of 35.97 μM [1] .

    价 格：￥电议型 号：T75503产 地：中国大陆

  • T73525ML202；化合物 ML202ML202

    ML202 is a highly specific allosteric activator of human pyruvate kinase M2 (hPK-M2), enhancing the cooperativity of phosphoenolpyruvate (PEP) binding, with negligible effect on adenosine diphosphate (ADP) binding.

    价 格：￥电议型 号：T73525产 地：中国大陆

  • T73523OUL245；化合物 OUL245OUL245

    OUL245, a 7-Hydroxy derivative, selectively inhibits PARP2 with an IC50 of 44 nM. Additionally, it exhibits inhibition against other PARP and TNKS enzymes, displaying IC50 values ranging from 2.9 to 8.8 μM.

    价 格：￥电议型 号：T73523产 地：中国大陆

  • T73496OUL232；化合物 OUL232OUL232

    OUL232 is a potent single ARTs PARP7, PARP10, PARP11, PARP12, PARP14 and PARP15 inhibitor for cancer and tumour research.

    价 格：￥电议型 号：T73496产 地：中国大陆

  • T73342Prenderol；化合物 Prenderol2,2-Diethyl-1,3-propanediol；2,2-Diethyl-1,3-propanediol

    Prenderol, a potent central-nervous-system (CNS) depressant, exhibits anticonvulsant activity.

    价 格：￥电议型 号：T73342产 地：中国大陆

  • T73264L2H2-6OTD；化合物 L2H2-6OTDL2H2-6OTD

    L2H2-6OTD, a telomeric inhibitor analogue characterized by containing one to four G-quadruplex binding loops, exhibits telomerase inhibitory activity with an IC 50 value of 15 nM.

    价 格：￥电议型 号：T73264产 地：中国大陆

  • T7214TEPP-46；化合物ML265ML265；ML265

    TEPP-46 (ML265) is a potent PKM2 activator (AC50 : 92 nM) showing little or no effect on PKM1, PKL and PKR,induces tetramerization and reduces tumor formation and size in a mouse xenograft model. .

    价 格：￥电议型 号：T7214产 地：中国大陆

  • T71772Bicifadine free base；化合物 Bicifadine free baseCL-220075|||Bicifadine free base|||CL220075|||Bicifadin

    Bicifadine, also known as DOV-220075, CL 220,075, is a SNDR inhibitor potentially for the treatment of lower back pain. Bicifadine has a non-opioid, non-NSAID mechanism for the treatment of pain, which should have less abuse potential than opioid drugs and less propensity to cause gastric ulcers than NSAID drugs. While the drug is purported to be a serotonin (SERT) and noradrenaline transporter (NET) inhibitor, it also has effects at the dopamine transporter (DAT), effectively making it a broad

    价 格：￥电议型 号：T71772产 地：中国大陆

  • T7175624(S),25-Epoxycholesterol；化合物 24(S),25-Epoxycholesterol24(S),25-Epoxycholesterol

    24(S),25-Epoxycholesterol is an oxysterol agonist of the liver X receptor.

    价 格：￥电议型 号：T71756产 地：中国大陆

  • T7148L2Josamycin propionate；化合物 T7148L2BRN 1677122|||BRN-1677122|||BRN1677122；BRN 1677122|||BRN-1677122|||B

    Josamycin propionate is a macrolide antibiotic.

    价 格：￥电议型 号：T7148L2产 地：中国大陆

  • T70786ML252；化合物 ML 252ML252

    ML252 is a selective potassium channel inhibitor, specifically targeting the KCNQ2 channel (Kv7.2) with an IC50 value of 69 nM. Additionally, ML252 demonstrates inhibitory activity against Cytochrome P450 isoforms, including IC50 values of 6.1 nM (CYP1A2), 18.9 nM (CYP2C9), 3.9 nM (CYP3A4), and 19.9 nM (CYP2D6).

    价 格：￥电议型 号：T70786产 地：中国大陆

  • T70632DFL23448；化合物 DFL23448DFL23448

    DFL23448 is a TRPM8-selective ion channel antagonist, modifying bladder function and reduces bladder overactivity in awake rats.

    价 格：￥电议型 号：T70632产 地：中国大陆

  • T6989SKL2001；化合物SKL2001SKL2001

    SKL2001, an agonist of the Wnt/β-catenin pathway, can disrupt the Axin/β-catenin interaction.

    价 格：￥电议型 号：T6989产 地：中国大陆

  • T6984SirReal2；化合物SirReal2SirReal2

    SirReal2 is a potent and selective Sirt2 inhibitor with IC50 of 140 nM.

    价 格：￥电议型 号：T6984产 地：中国大陆

  • T69304MRL20；化合物 MRL20MRL20

    MRL20 is a selective PPARγ modulator (SPPARγM) which displays robust anti-diabetic activity with an improved therapeutic window in comparison to a PPARγ full agonist in a rodent efficacy model.

    价 格：￥电议型 号：T69304产 地：中国大陆

  • T69163BML277 Acid；化合物 BML277 AcidBML277 Acid

    BML277 Acid is a metabolite of BML277 which is a selective checkpoint kinase 2 inhibitor.

    价 格：￥电议型 号：T69163产 地：中国大陆

  • T69149L2-b；化合物 L2-bL2-b

    L2-b is a bifunctional Aβ-interacting, metal-chelating molecule that modulates ROS production in, and improves survival of neuroblastoma cells incubated in the presence of Aβ along with Copper or Zinc. In cell-free aggregation studies, L2-b inhibits metal-induced Aβ aggregation, and also promotes the dissociation of Ab aggregates in homogenates of human AD brain samples.

    价 格：￥电议型 号：T69149产 地：中国大陆

  • T6894ML264；化合物ML264CID-51003603；CID-51003603

    ML264 (CID-51003603) is a selective kruppel-like factor 5 (KLF5) inhibitor, which potently Inhibits growth of Colorectal Cancer.

    价 格：￥电议型 号：T6894产 地：中国大陆

  • T6818DEL-22379；化合物DEL22379DEL22379；DEL22379

    DEL-22379 is a water-soluble ERK dimerization inhibitor with IC50 of ～0.5 μM.

    价 格：￥电议型 号：T6818产 地：中国大陆

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