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产品数:86101
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TN1067GalloylpaeoniflorinNuclear factor-kappaB,inhibit,Inhibitor,Galloylpaeoniflorin,NF-κB,Nuclear factor-
Galloylpaeoniflorin may be developed as a cytoprotector against ROS-mediated oxidative stress. Galloylpaeoniflorin is also an inhibtior of NF-κB and DNA cleavage.
价 格:¥电议型 号:TN1067产 地:中国大陆
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T9689M4205factor,M-4205,receptor,M4205,cell,CD117,growth,inhibit,mast/stem,mutations,SCFR,c-Kit,M 4205,In
M4205 is an inhibitor of c-Kit exhibiting high activity on c-Kit mutations in exons 11, 13, 17.
价 格:¥电议型 号:T9689产 地:中国大陆
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T8872(Rac)-JBJ-04-125-02Allosteric,anti-proliferation,HER1,inhibit,ErbB-1,(Rac)JBJ0412502,Inhibitor,racem
JBJ-04-125-02 is effective as a single agent in both in vitro and in vivo models of EGFR-mutant lung cancer.
价 格:¥电议型 号:T8872产 地:中国大陆
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T9195SHR0302Th17,SHR-0302,B-cell,Inhibitor,inhibit,arthritis,collagen,migration,hepatic,SHR0302,JAK1,phos
SHR0302 is a JAK inhibitor that binds JAK1 with stronger affinity than others (Selectivity for JAK1 is more than 10 times for JAK2, 77 times for JAK3, 420 times for Tyk2).
价 格:¥电议型 号:T9195产 地:中国大陆
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T33817OrellanineOrellanine
Orellanine is a nephrotoxic compound extracted from the mushroom Cortinarius orellanus. Orellanine strongly inhibits the synthesis of macromolecules (Proteins, RNA and DNA) in Madin-Darby canine kidney cells and in rat liver mitochondria.
价 格:¥电议型 号:T33817产 地:中国大陆
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T9370dCBP-1Inhibitor,p300,multiple,CRBN,myeloma,cell,degrader,PROTACs,MYC,CBP,inhibit,dCBP 1,dCBP1,hetero
dCBP-1 is a chemical degrader of p300/CBP. dCBP-1 hijacks the E3 ubiquitin ligase CRBN for selective degradation of p300/CBP. Degradation of p300/CBP by dCBP-1 leads to effective multiple myeloma cell killing.
价 格:¥电议型 号:T9370产 地:中国大陆
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T9135EpirosmanolEpirosmanol,inhibit,melanoma cells,scavenging activity,melanin,Inhibitor,antioxidant,dite
Epirosmanol belongs to the class of organic compounds known as diterpene lactones. These are diterpenoids containing a lactone moiety. Epirosmanol is an extremely weak basic (essentially neutral) compound (based on its pKa).
价 格:¥电议型 号:T9135产 地:中国大陆
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TP1328TB500cell differentiation,keratinocyte migration,TB500,collagen deposition,TB 500,TB-500,thymosin β
TB-500 is a synthesised peptide, essentially a short-chain version of the naturally occurring Thymosin Beta-4.
价 格:¥电议型 号:TP1328产 地:中国大陆
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TN2258Tartrazineinhibit,Inhibitor,Acid Yellow-23,Tartrazine,Acid Yellow23
Tartrazine is a food additive that belongs to a class of artificial dyes and contains an azo group; it has significant genotoxic effect , may be harmful to health and its prolonged use could trigger carcinogenesis.
价 格:¥电议型 号:TN2258产 地:中国大陆
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T0161Pantoprazole Sodium HydrateSKF96022 sodium,Inhibitor,stability,orally,Pantoprazole Sodium Hydrate,A4
Pantoprazole is a proton pump inhibitor drug, used for short-term treatment of erosion and ulceration of the esophagus caused by gastroesophageal reflux disease.
价 格:¥电议型 号:T0161产 地:中国大陆
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T6905Netupitantorally,Neurokinin Receptor,Tachykinin receptor,Netupitant,Inhibitor,substance P,NK recepto
Netupitant is a specific neurokinin 1 (NK1) receptor antagonist (Ki: 0.95 nM).
价 格:¥电议型 号:T6905产 地:中国大陆
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T9216MLT-943MLT 943,inflammation,paw swelling,MALT1,MLT-943,inhibit,Inhibitor,mucosa associated lymphoid
MLT-943 is a potent, selective and orally active MALT1 protease inhibitor. [1].
价 格:¥电议型 号:T9216产 地:中国大陆
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T8546BD750Immunosuppressant,JAK,BD750,cell,Janus kinase,BD-750,inhibit,STAT,Inhibitor,BD 750
BD750 is an effective immunosuppressant and a JAK3/STAT5 inhibitor, inhibits IL-2-induced JAK3/STAT5-dependent T cell proliferation(IC50 of 1.5 μM and 1.1 μM in mouse and human T cells, respectively)
价 格:¥电议型 号:T8546产 地:中国大陆
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T6690T0901317orally,fibroblasts,FXR,LXRβ,T0901317,foreskin,T 0901317,Liver X receptor,atherosclerosis,LDL
T0901317 is a potent and selective agonist for both LXR and FXR, with EC50 of ~50 nM and 5 μM, respectively; it inhibits nuclear factor/κB (NF/κB).
价 格:¥电议型 号:T6690产 地:中国大陆
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T8847Fosravuconazole L-lysine ethanolateFungal,onychomycosis,Fosravuconazole Llysine ethanolate,Parasite,
FosravuconazoleL-lysine ethanolate is a broad-spectrum antifungal agent. In Japan, it is approved for the treatment of onychomycosis, a fungal infection of the nail. It is a prodrug that is converted into ravuconazole.
价 格:¥电议型 号:T8847产 地:中国大陆
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TP1904LFSLLRY-NH2 TFA(245329-02-6 free base)FSLLRY NH2 TFA(245329 02 6 free base),FSLLRY-NH-2 TFA(245329-02
FSLLRY-NH2 TFA is a is a protease-activated receptor 2 (PAR2) inhibitor. Reverses taxol-induced mechanical allodynia, heat hyperalgesia and PKC activation in ICR mice. Blocks ERK activation and collagen production in isolated cardiac fibroblasts. Also reduces symptoms in a mouse model of dermatophyte-associated itch.
价 格:¥电议型 号:TP1904L产 地:中国大陆
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TN12553-O-Acetyl-11-hydroxy-beta-boswellic acidLipoxygenase,3OAcetyl11hydroxybetaboswellic acid,LOX,Inhibi
3-O-Acetyl-11-hydroxy-beta-boswellic acid is the precursor of 3-O-acetyl-9, 11-dehydro-beta-boswellic acid(a 5-lipoxygenase inhibitor ).
价 格:¥电议型 号:TN1255产 地:中国大陆
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T9564IRE1α kinase-IN-1endoribonuclease,Inositol requiring enzyme 1,cells,IRE1,oligomerization,IRE-1α kina
IRE1α kinase-IN-1 is a highly selective IRE1α (ERN1) inhibitor, with an IC50 of 77 nM. It displays 100-fold selectivity for IRE1α over the IRE1β isoform. It inhibits ER stress-induced IRE1α oligomerization and autophosphorylation, and also inhibits IRE1α RNase activity (IC50=80 nM)
价 格:¥电议型 号:T9564产 地:中国大陆
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T11492GSK2983559 free acidinhibit,THP-1 cell,RIP kinase,GSK 2983559,GSK2983559 free acid,Inhibitor,GSK-298
GSK2983559 free acid is an effective and selective inhibitor of receptor-interacting protein 2 (RIP2). GSK2983559 free acid shows excellent activity in blocking many proinflammatory cytokine responses in human inflammatory bowel disease explant samples an
价 格:¥电议型 号:T11492产 地:中国大陆
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T9933Methyl 2,4-dihydroxyphenylacetateInhibitor,Methyl 2,4dihydroxyphenylacetate,Nigella damascena seeds,
Methyl 2,4-dihydroxyphenylacetate is a natural product isolated from Nigella damascena seeds with selective phytotoxic effects.
价 格:¥电议型 号:T9933产 地:中国大陆