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T39794Bisabolone oxide A；Bisabolone oxide ABisabolone oxide A
Bisabolone oxide A is an α-glucosidase inhibitor.
价 格：￥电议型 号：T39794产 地：中国大陆
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T38606Sinapine hydroxide；Sinapine hydroxideSinapine hydroxide
Sinapine hydroxide, an alkaloid derived from the seeds of cruciferous plants, demonstrates a variety of beneficial properties including anti-inflammatory, anti-oxidant, anti-tumor, anti-angiogenic, and radio-protective effects. Additionally, it acts as an inhibitor of acetylcholinesterase (AChE), making it valuable for researching neurodegenerative conditions such as Alzheimer’s disease, ataxia, myasthenia gravis, and Parkinson’s disease[4].
价 格：￥电议型 号：T38606产 地：中国大陆
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T38400Triclabendazole sulfoxide；三氯苯达唑亚砜TCBZ-SO；TCBZ-SO|||三氯苯达唑亚砜
Triclabendazole sulfoxide (TCBZ-SO) is a main plasma metabolite of Triclabendazole. Triclabendazole sulfoxide inhibits membrane transporter ABCG2/BCRP and exhibits anti-parasite effects.
价 格：￥电议型 号：T38400产 地：中国大陆
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T38134(S)-O-Desmethyl Venlafaxine N-Oxide；S-O-去甲-文拉法辛N-氧化物(S)-O-Desmethyl Venlafaxine N-Oxide
(S)-O-Desmethyl Venlafaxine N-Oxide, an N-oxide derivative of (S)-O-Desmethyl Venlafaxine, constitutes an active metabolite of the serotonin-norepinephrine reuptake inhibitor (SNRI) class antidepressant, Venlafaxine[1][2].
价 格：￥电议型 号：T38134产 地：中国大陆
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T38058Cimetidine sulfoxide；西咪替丁亚砜Cimetidine sulfoxide
Cimetidine sulfoxide (Cimetidine sulphoxide) is a metabolite of Cimetidine, functioning as a histamine H2-receptor antagonist with potential applications in treating peptic ulcer disease and upper gastrointestinal hemorrhage[1].
价 格：￥电议型 号：T38058产 地：中国大陆
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T38003Levofloxacin N-oxide；左氧氟沙星N-氧化物Levofloxacin N-oxide
Levofloxacin N-oxide is an impurity isolated from levofloxacin.
价 格：￥电议型 号：T38003产 地：中国大陆
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T37796Voriconazole N-oxide；Voriconazole N-oxideVoriconazole N-oxide
Voriconazole N-oxide is a major metabolite of the triazole antifungal voriconazole . It is formed via oxidation of voriconazole by the cytochrome P450 (CYP) isoforms CYP3A4 and CYP2C19.
价 格：￥电议型 号：T37796产 地：中国大陆
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T37643Propiverine N-oxide (hydrochloride)；Propiverine N-oxide (hydrochloride)Propiverine N-oxide (hydrochl
Propiverine N-oxide (hydrochloride) is the major metabolite of propiverine in human plasma or urine.
价 格：￥电议型 号：T37643产 地：中国大陆
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T37639Toltrazuril sulfoxide；Toltrazuril sulfoxideToltrazuril sulfoxide
Toltrazuril sulfoxide, a transient intermediary metabolite of Toltrazuril, undergoes in vivo metabolism to yield the reactive toltrazuril sulfone (TZR-SO2). Toltrazuril functions as an antiprotozoal agent targeting Coccidia parasites[1].
价 格：￥电议型 号：T37639产 地：中国大陆
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T37600Dasatinib N-oxide；达沙替尼N氧化物Dasatinib N-oxide
Dasatinib N-oxide is a major metabolite of the Abl and Src kinase inhibitor dasatinib.It is also a potential impurity in commercial preparations of dasatinib[1][2].
价 格：￥电议型 号：T37600产 地：中国大陆
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T37430Mirtazapine N-oxide；Mirtazapine N-oxideMirtazapine N-oxide
Mirtazapine N-oxide is a metabolite of mirtazapine.1It is formed from mirtazapine by the cytochrome P450 (CYP) isoforms CYP1A2 and CYP3A4 in human liver microsomes.
价 格：￥电议型 号：T37430产 地：中国大陆
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T37246Palonosetron N-oxide；Palonosetron N-oxidePalonosetron N-oxide
Palonosetron N-oxide is a metabolite of the serotonin (5-HT) receptor subtype 5-HT3antagonist palonosetron .1It is also a potential impurity in palonosetron preparations.2Palonosetron N-oxide is a degradation product formed by exposure to oxidative stress.
价 格：￥电议型 号：T37246产 地：中国大陆
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T37149Carbamazepine 10,11-epoxide；卡马西平 10,11-环氧化物Carbamazepine 10,11-epoxide
Carbamazepine 10,11-epoxide is an active metabolite of the anticonvulsant carbamazepine[1][2].It is formed from carbamazepine by the cytochrome P450 (CYP) isoforms CYP3A4 and CYP2C8 in microsomes prepared from HepG2 cells expressing CYP3A4 or CYP2C8, respectively[1].Carbamazepine 10,11-epoxide has anticonvulsant activity against maximal electroshock-induced seizures in mice.2It has been found in wastewater effluent[3].
价 格：￥电议型 号：T37149产 地：中国大陆
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T36795Donepezil N-oxide；Donepezil N-oxideDonepezil N-oxide
Donepezil N-oxide is an active metabolite of the acetylcholinesterase inhibitor donepezil . Donepezil N-oxide inhibits cholinesterase (ChE) activity in human erythrocytes in a concentration-dependent manner, exhibiting 45.5% inhibition when used at a concentration of 20 μM.
价 格：￥电议型 号：T36795产 地：中国大陆
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T36730Vitamin K1 2,3-epoxide；维他命 K1 2,3-环氧化物Vitamin K1 epoxide|||Phylloquinone oxide|||Vitamin K1 2,3-epox
Vitamin K1 2,3-epoxide (Phylloquinone oxide) is reduced to vitamin k and is involved in the vitamin k cycle.
价 格：￥电议型 号：T36730产 地：中国大陆
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T36681Sorafenib N-oxide；Sorafenib N-oxideSorafenib N-oxide
Sorafenib N-oxide is an active metabolite of sorafenib , an inhibitor of Raf-1, B-RAF, and receptor tyrosine kinases. Sorafenib N-oxide inhibits FLT3 that contains the internal tandem duplication mutation (FLT3-ITD; Kd = 70 nM) and inhibits proliferation of MV4-11 acute myeloid leukemia (AML) cells expressing FLT3-ITD (IC50 = 25.8 nM). It is selective for AML cell lines containing FLT3-ITD over lines containing wild-type FLT3 (IC50s = 3.9-13.3 μM). Sorafenib N-oxide is also a linear-mixed inhibi
价 格：￥电议型 号：T36681产 地：中国大陆
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T36137Biotin (S)-sulfoxide；Biotin (S)-sulfoxideBiotin (S)-sulfoxide
Biotin (S)-sulfoxide is an inactive metabolite of the coenzyme biotin .1,2It has also been found inE. coliand is reduced by the biotin sulfoxide reduction system as a source of biotin.3
价 格：￥电议型 号：T36137产 地：中国大陆
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T36136Biotin (R)-Sulfoxide；Biotin (R)-SulfoxideBiotin (R)-Sulfoxide
Biotin (R)-sulfoxide is a metabolite of the coenzyme biotin .1
价 格：￥电议型 号：T36136产 地：中国大陆
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T35973Cholesterol-5α,6α-epoxide；胆固醇-5Α,6Α-环氧化物Epoxycholesterol|||5α,6α-epoxy Cholestanol|||NSC 18176；Epoxy
Cholesterol-5α,6α-epoxide (Epoxycholesterol) is the metabolite of cholesterol produced by oxidation. Cholesterol-5α,6α-epoxide induces triacylglycerol biosynthesis by binding to LXRβ following tamoxifen and PBPE application.
价 格：￥电议型 号：T35973产 地：中国大陆
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T35882Rizatriptan N-oxide；Rizatriptan N-oxideRizatriptan N-oxide
Rizatriptan N-oxide is a potential impurity found in commercial preparations of rizatriptan.1It is a degradation product formed under oxidative conditions.
价 格：￥电议型 号：T35882产 地：中国大陆
