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T4546Dinoprost tromethamine salt;地诺前列素氨丁三醇Dinoprost Tromethamine|||Zinoprost|||Prostin F2 alpha|||PGF2α T
Dinoprost tromethamine salt (PGF2α THAM) is a naturally occurring prostaglandin used in medicine to induce labor and as an abortifacient.
价 格:¥电议型 号:T4546产 地:中国大陆
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T4259GLPG0187;化合物GLPG0187GLPG0187
GLPG0187, a broad spectrum integrin receptor antagonist, inhibits αvβ1-integrin (IC50: 1.3 nM).
价 格:¥电议型 号:T4259产 地:中国大陆
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T41267PROTAC(H-PGDS)-7;化合物 PROTAC(H-PGDS)-7PROTAC(H-PGDS)-7
PROTAC(H-PGDS)-7 is a selective and potent small molecule hematopoietic prostaglandin D synthase (H-PGDS) PROTAC degradation agent that exhibits degradation activity in KU812 cells with a DC50 of 17.3 pM. PROTAC(H-PGDS)-7 is a pharmacological compound that effectively inhibits prostaglandin D2 (PGD2) PROTAC(H-PGDS)-7 is a candidate compound for the treatment of DMD and other H-PGDS-related diseases.
价 格:¥电议型 号:T41267产 地:中国大陆
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T4041Ziritaxestat;化合物GLPG1690GLPG1690;GLPG1690
Ziritaxestat (GLPG1690), an autotaxin inhibitor, currently being evaluated in an exploratory phase 2 study in idiopathic pulmonary fibrosis patients.
价 格:¥电议型 号:T4041产 地:中国大陆
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T3S1866Propyl gallate;没食子酸丙酯Tenox PG|||n-Propyl gallate|||Gallic acid propyl esterZ;没食子酸丙酯;3,4,5-三羟基苯甲酸丙酯、倍
Propyl gallate (Gallic acid propyl esterZ) is an antioxidant used in foods especially animal fats and vegetable oils, also in a wide variety of cosmetics and beauty care products.
价 格:¥电议型 号:T3S1866产 地:中国大陆
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T39633Navocaftor;NavocaftorGLPG 3067|||ABBV-3067;GLPG 3067|||ABBV-3067
Navocaftor, as a cystic fibrosis transmembrane regulator ( CFTR ), is a protein modulator (US 20200377491 Al, example 1).
价 格:¥电议型 号:T39633产 地:中国大陆
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T39521LEESGGGLVQPGGSMK;LEESGGGLVQPGGSMKLEESGGGLVQPGGSMK
LEESGGGLVQPGGSMK, a proteolysis peptide, is a constituent of Infliximab, a chimeric monoclonal IgG1 antibody that selectively binds to TNF-α. It can be employed for quantitative assessment of Infliximab.
价 格:¥电议型 号:T39521产 地:中国大陆
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T38714Boc-NH-PPG2;Boc-NH-PPG2Boc-NH-PPG2;Boc-NH-PPG2
Boc-NH-PPG2 is a alkyl/ether-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T38714产 地:中国大陆
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T38307tetranor-PGJM;tetranor-PGJMtetranor-PGJM
Tetranor-PGJM is a metabolite of prostaglandin D2 and is associated with the anti-inflammatory effects of curcumin.
价 格:¥电议型 号:T38307产 地:中国大陆
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T38306tetranor-PGDM;tetranor-PGDMtetranor-PGDM
Prostaglandin D2 is synthesized by hematopoietic-type PGD-synthase (H-PGDS) in mast cells and is released in large quantities during allergic and asthmatic anaphylaxis. PGD2 is also produced in the brain by lipocalin-PGD-synthase also known as β-trace. In the brain, PGD2 produces normal physiological sleep and lowering of body temperature. Further pharmacological actions include inhibition of platelet aggregation and relaxation of vascular smooth muscle. tetranor-PGDM is a major metabolite of PG
价 格:¥电议型 号:T38306产 地:中国大陆
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T38305tetranor-PGAM;tetranor-PGAMtetranor-PGAM
Prostaglandin E2 (PGE2), one of the most widely investigated PGs, can be used as a biomarker of inflammation, disease state, or therapeutic effectiveness. However due to its rapid metabolism, direct measurement of PGE2 in biological samples is difficult. The major urinary metabolite of PGE2, tetranor-PGEM, serves as an indirect marker of PGE2 biosynthesis. Though like PGE2, tetranor-PGEM is also chemically unstable. tetranor-PGAM is a dehydration product of tetranor-PGEM and can be measured as a
价 格:¥电议型 号:T38305产 地:中国大陆
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T38257PGDM;PGDMPGDM
Prostaglandin D2 (PGD2) plays a pharmacological role in allergic and asthmatic anaphylaxis, normal physiological sleep and lowering of body temperature, as well as inhibits platelet aggregation and relaxes vascular smooth muscle. PGDM is a major urinary metabolite of PGD2 with a unique lower sidechain that readily undergoes reversible cyclization. It is used as a biomarker to assess endogenous production of PGD2.
价 格:¥电议型 号:T38257产 地:中国大陆
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T38194Prostaglandin E3;Prostaglandin E3PGE3;PGE3
Prostaglandin E3 (PGE3) is formed via the cyclooxygenase (COX) metabolism of eicosapentaenoic acid. [1] In human ocular tissue, it comprises 2.4% of the COX products formed. [1] When applied to the eyes of a rabbit, a 1 µg dose of PGE3 decreases intraocular pressure from 21 mmHg to about 17 mmHg.[2]
价 格:¥电议型 号:T38194产 地:中国大陆
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T3799115-keto Prostaglandin F2α;化合物15-keto Prostaglandin F2α15-keto Prostaglandin F2α|||15-keto PGF2α;15-k
15-keto Prostaglandin F2α is a metabolite of Prostaglandin F2α that lowers intraocular pressure in rabbits.
价 格:¥电议型 号:T37991产 地:中国大陆
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T37919Prostaglandin F1α;Prostaglandin F1αPGF1α|||Prostaglandin F1α;PGF1α|||Prostaglandin F1α
Prostaglandin F1α (PGF1α) is the putative metabolite of dihomo-γ-linolenic acid (DGLA) via the cyclooxygenase (COX) pathway. Both PGF1α and PGF2α have been shown to act as priming pheromones for male Atlantic salmon with a threshold concentration of 10-11 M. [1] PGF1α binds to the ovine corpus luteum FP receptor at only 8% of the relative potency of PGF2α. [2] It is only half as active as PGF2α in inducing human respiratory smooth muscle contractions in vitro. [3]
价 格:¥电议型 号:T37919产 地:中国大陆
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T37834G3-CNP;化合物 G3-CNPG3-CNP
G3-CNP is a colorimetric substrate for α-amylases.1Upon hydrolysis by α-amylases, 2-chloro-4-nitrophenol is released which can be quantified by colorimetric detection at 405 nm as a measure of enzyme activity. G3-CNP has been used to characterize the activity of human pancreatic or salivary amylase.
价 格:¥电议型 号:T37834产 地:中国大陆
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T37773tetranor-PGEM;tetranor-PGEMtetranor-Prostaglandin E Metabolite|||tetranor-PGEM;tetranor-Prostaglandi
tetranor-PGEM is the major urinary metabolite of PGE1 and PGE2, and is used as a marker of PGE2 biosynthesis.[1],[2] About 15% of an infused dose of PGE2 appears as this metabolite in the urine of humans. Normal healthy males excrete 7-40 μg of tetranor-PGEM over a 24-hour period.[1]
价 格:¥电议型 号:T37773产 地:中国大陆
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T37575GLcNAc1-b-PNP;化合物GLcNAc1-b-PNPGLcNAc1-b-PNP
GLcNAc1-b-PNP is a chromogenic substrate for N-acetyl-β-glucosaminidase and can be used to quantify the activity of N-acetyl-β-D-glucosaminidase in human serum and urine.
价 格:¥电议型 号:T37575产 地:中国大陆
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T37326Prostaglandin F2α 1,11-lactone;化合物T37326Prostaglandin F2α 1,11-lactone|||PGF2α 1,11-lactone;Prostagl
Prostaglandin F2α 1,11-lactone (PGF2α 1,11-lactone) is a lipid-soluble prodrug of Prostaglandin F2α and can be used in studies about treating glaucoma. Prostaglandin F2α 1,11-lactone is active as an antifertility agent with greatly reduced vasoactivity.
价 格:¥电议型 号:T37326产 地:中国大陆
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T3726415(R)-15-methyl Prostaglandin D2;化合物 T3726415(R)15methyl PGD2;15(R)15methyl PGD2
15(R)-15-methyl Prostaglandin D2 (15(R)15methyl PGD2) is a synthetic analogue of PGD2 and a selective and potent CRTH2/DP2 receptor agonist that modulates eosinophil CD11b expression, actin polymerisation and chemotaxis.
价 格:¥电议型 号:T37264产 地:中国大陆