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T28475Pyrazoloacridinetumor,Inhibitor,leukemia,inhibit,solid,Apoptosis,NSC366140,carcinoma,Pyrazoloacridin
Pyrazoloacridine is a nucleic acid binding agent that inhibits the activity of topo I and II with an IC50 of 1.25 μM in K562 cells. Pyrazoloacridine shows anti-cancer activity.
价 格:¥电议型 号:T28475产 地:中国大陆
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T8719SC99orally,ERK,c-Src,SC 99,ATP-binding,phosphorylation,platelet,AKT,Janus kinase,activation,anti-mye
SC99 is a selective inhibitor of JAK2-STAT3 activation. SC99 downregulates the expression of STAT3-modulated genes.SC99 inhibits platelet activation, aggregation and displays potent anti-myeloma, anti-thrombotic activities
价 格:¥电议型 号:T8719产 地:中国大陆
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T9949NSC 370284NSC 370284
NSC 370284 is a small molecule that directly binds to and inhibits STAT3/5, significantly and selectively suppresses the viability of AML cells with high level of TET1 expression both in vitro and in vivo.
价 格:¥电议型 号:T9949产 地:中国大陆
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T7212Delavirdine mesylatepolymerase,BHAP-U 90152,U90152,U 90152,Inhibitor,Reverse Transcriptase,Delavirdi
Delavirdine (mesylate) is a non-nucleoside reverse transcriptase inhibitor (NNRTI).
价 格:¥电议型 号:T7212产 地:中国大陆
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T8972FIT-039Cytomegalovirus,HSV-1,Herpes simplex virus,transcription,Inhibitor,DNA,CDK,Cyclin dependent k
FIT-039 is a selective and ATP-competitive, orally active inhibitor of CDK9( IC50 : 5.8 μM;CDK9/cyclin T1). FIT-039 inhibits replication of HSV-1 (IC50 of 0.69 μM), HSV-2, human adenovirus, and human CMV. FIT-039 is a promising antiviral agent for inhibiting drug-resistant HSVs and other DNA viruses.
价 格:¥电议型 号:T8972产 地:中国大陆
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T8452Dantrolenemuscle spasticity,F368,inhibit,Inhibitor,neuroleptic malignant syndrome,F-368,Huntington’s
Dantrolene is a postsynaptic muscle relaxant by inhibiting Ca2+ ions release from sarcoplasmic reticulum stores by antagonizing ryanodine receptors.
价 格:¥电议型 号:T8452产 地:中国大陆
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T8531m-3M3FBScalcium,superoxide,cells,THP-1,phosphate,m 3M3FBS,m-3M3FBS,Apoptosis,Inhibitor,m3M3FBS,Phosp
m-3M3FBS is a phospholipase C (PLC) activator.
价 格:¥电议型 号:T8531产 地:中国大陆
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TN67541-NonadecanolHeracleum,carbon,Inhibitor,ustulata,inhibit,thomsonii,dioxide,1-Nonadecanol,SC-CO2,arom
1-Nonadecanol is a saturated fatty alcohol. 1-Nonadecanol is one of the compositions of supercritical carbon dioxide (SC-CO2) essential oil of Heracleum thomsonii. 1-Nonadecanol is also an important aroma compound in Neotinea ustulata.
价 格:¥电议型 号:TN6754产 地:中国大陆
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T9920EvolocumabAMG-145,Ser/Thr Protease,Repatha,AMG 145,inhibit,atherosclerotic cardiovascular disease,Se
Evolocumab is a human IgG2 monoclonal antibody that binds to human PCSK9 Proprotein Convertase Subtilisin Kexin Type 9).
价 格:¥电议型 号:T9920产 地:中国大陆
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T7780Blarcamesinesyndrome,Inhibitor,Muscarinic acetylcholine receptor,inhibit,mAChR,Rett,anticonvulsant,B
AVex-73 is a muscarinic M1 agonist potentially for the treatment of Alzheimer´s disease.
价 格:¥电议型 号:T7780产 地:中国大陆
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T9460iMDKinhibit,iMDK,midkine,factor,PI3K,NSCLC,growth,Inhibitor,Phosphoinositide 3-kinase,MDK
iMDK quarterhydrate is a potent PI3K inhibitor that inhibits the growth factor MDK (also known as midkine or MK). iMDK quarterhydrate synergistically inhibits non-small cell lung cancer (NSCLC) with MEK inhibitors without harming normal cells and mice.
价 格:¥电议型 号:T9460产 地:中国大陆
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T9061EN4EN4,ligand,Myc,tumorigenesis,transcriptional,inhibit,Inhibitor,EN 4,covalent,C171,c-Myc,EN-4
EN4 MYC inhibitor is a covalent ligand that targets cysteine 171 (C171) of MYC. It is selective for c-MYC over N-MYC and L-MYC, and inhibits MYC transcriptional activity, downregulates MYC targets, and impairs tumorigenesis.
价 格:¥电议型 号:T9061产 地:中国大陆
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T7104Dovitinib lactateFGFR,CHIR-258,Dovitinib,c-Kit,SCFR,PDGFR,CD117,Platelet-derived growth factor recep
Dovitinib lactate(TKI258) lactate is a potent inhibitor of fibroblast growth factor receptor 3 (FGFR3) (IC50 :5 nM).
价 格:¥电议型 号:T7104产 地:中国大陆
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T60098MSC2504877
MSC2504877 is an inhibitor of tankyrase and enhances the effects of clinical CDK4/6 inhibitors. MSC2504877 suppresses the upregulation of Cyclin D2 and Cyclin E2 caused by palbociclib and enhances the suppression of phospho-Rb.
价 格:¥电议型 号:T60098产 地:中国大陆
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T8295Sclareol glycolSclareol glycol,Inhibitor,Precursor,20624,ambroxide,Hyphozyma,inhibit,ATCC,roseonigra
Sclareol glycol is the precursor of ambroxide.
价 格:¥电议型 号:T8295产 地:中国大陆
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T78878-Hydroxyquinoline hemisulfatetranscription,inhibitor,inhibit,8-Hydroxyquinoline hemisulfate,8-Quino
Oxyquinoline sulfate is an antiseptic with mild fungistatic, bacteriostatic, anthelmintic, and amebicidal action
价 格:¥电议型 号:T7887产 地:中国大陆
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T7884NS 1738NS 1738,Nicotinic acetylcholine receptors,NSC213859,inhibit,Inhibitor,nAChR,NS-1738,NSC-21385
NS 1738 is a positive allosteric modulator of the α7-containing neuronal nicotinic acetylcholine receptors (nAChRs)
价 格:¥电议型 号:T7884产 地:中国大陆
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T7655FialuridineFialuridine,NSC678514,DRG 0098,Orthopoxvirus,DNA/RNA Synthesis,DRG0098,inhibit,NSC 678514
Fialuridine is a DNA-directed DNA polymerase inhibitor potentially for the treatment of HBV infection with potent activity against hepatitis B virus in vitro and in vivo.
价 格:¥电议型 号:T7655产 地:中国大陆
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TP1197SincalidePI3K/Akt,cardiovascular hormone,Inhibitor,SQ 19844,PI3K,Akt,Protein kinase B,Apoptosis,SQ-1
Sincalide (INN) is a cholecystokinetic drug administered by injection to aid in diagnosing disorders of the gallbladder and pancreas. It is the 8-amino acid C-terminal fragment of cholecystokinin, and also known as CCK-8.
价 格:¥电议型 号:TP1197产 地:中国大陆
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T6S1930SchisanhenolInhibitor,Schisanhenol,inhibit
1. Schisanhenol can protect against adriamycin induced heart mitochondrial toxicity. 2. Schisanhenol has antioxidative effect on human LDL oxidation, may be through scavenging free radicals. 3. Schisanhenol has anti-apoptosis effect on BACSs, may be related to its inhibition of ROS generation.
价 格:¥电议型 号:T6S1930产 地:中国大陆