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  • T7347CU-CPT-8m；化合物CU-CPT-8mTLR8-specific antagonist；TLR8-specific antagonist

    CU-CPT-8m (TLR8-specific antagonist) is an toll-like receptor 8 (TLR8) antagonist (IC50 : 67 nM)

    价 格：￥电议型 号：T7347产 地：中国大陆

  • T73443STL1267；化合物 STL1267STL1267

    STL1267, a potent REV-ERB agonist capable of crossing the blood-brain barrier, exhibits a K i value of 0.16 ?M for REV-ERBα without demonstrating cytotoxicity. It effectively inhibits the gene expression of BMAL1.

    价 格：￥电议型 号：T73443产 地：中国大陆

  • T7302CU-CPT9b；化合物CU-CPT9bCU-CPT-9b|||TLR8-specific antagonist 1；CU-CPT-9b|||TLR8-specific antagonist 1

    CU-CPT9b (TLR8-specific antagonist 1) is an antagonist of toll-like receptor 8 (TLR8; Kd = 21 nM). It inhibits activation of NF- B induced by the TLR8 agonist R-848 in TLR8-overexpressing HEK-Blue cells with an IC50 value of 0.7 nM.

    价 格：￥电议型 号：T7302产 地：中国大陆

  • T73004METTL3-IN-3；化合物 METTL3-IN-3METTL3-IN-3

    METTL3-IN-3 is a polyheterocyclic compound, acts as METTL3 inhibitor [1] .

    价 格：￥电议型 号：T73004产 地：中国大陆

  • T73003METTL3-IN-2；化合物 METTL3-IN-2METTL3-IN-2

    METTL3-IN-2, a potent METTL3 inhibitor, exhibits an IC50 value of 6.1 nM, effectively impairing the proliferation of Caov3 cancer cells.

    价 格：￥电议型 号：T73003产 地：中国大陆

  • T73002METTL3-IN-1；化合物 METTL3-IN-1METTL3-IN-1

    METTL3-IN-1 is a polyheterocyclic compound, acts as METTL3 inhibitor [1] .

    价 格：￥电议型 号：T73002产 地：中国大陆

  • T72830TLR8 agonist 5；化合物 TLR8 agonist 5TLR8 agonist 5

    TLR8 Agonist 5, exhibiting potent efficacy as a TLR8 agonist, demonstrates an EC50 of 20 nM in HEK-Blue hTLR8, effectively activating the immune response.

    价 格：￥电议型 号：T72830产 地：中国大陆

  • T72684TLR7/8 agonist 7；化合物 TLR7/8 agonist 7TLR7/8 agonist 7

    TLR7/8 agonist 7, a compound that functions as a TLR7/8 agonist, plays a pivotal role in activating various immune cells and is instrumental in the synthesis of immune-stimulating antibody conjugate (ISAC) molecules. This compound holds significant potential for research in immunology.

    价 格：￥电议型 号：T72684产 地：中国大陆

  • T72548IGUANA-1 free base；化合物 IGUANA-1 free baseSTL5-T-0057；STL5-T-0057

    IGUANA-1 free base (STL5-T-0057) acts as a selective ALDH1 B1 inhibitor, demonstrating an IC50 value of 30 nM. It efficaciously inhibits the growth of SW480 cells under both adherent and spheroid conditions, yielding IC50 values of 2.46 μM and 0.39 μM, respectively. This compound is utilized in cancer research.

    价 格：￥电议型 号：T72548产 地：中国大陆

  • T71762TLSC702；化合物 TLSC702TLSC702

    TLSC702 is a novel Inhibitor of Human Glyoxalase I, Inducing Apoptosis in Tumor Cells.

    价 格：￥电议型 号：T71762产 地：中国大陆

  • T71108TLR7/8 agonist 1；化合物 TLR7/8 agonist 7dTLR7/8 agonist 1

    TLR7/8 agonist 1 is a toll-like receptor ( TLR7 )/ TLR8 dual-agonistic imidazoquinoline.

    价 格：￥电议型 号：T71108产 地：中国大陆

  • T70905TLR9-IN-18；化合物 TLR9-IN-18TLR9-IN-18

    TLR9-IN-18 is a potent and selective TLR9 antagonist. TLR9-IN-18 suppresses the production of the proinflammatory cytokine IL-6 in a CpG-induced mouse model.

    价 格：￥电议型 号：T70905产 地：中国大陆

  • T70540Pinokalant；化合物PinokalantLOE-908；LOE-908

    Pinokalant (LOE-908) is a novel non-selective cation channel inhibitor.Pinokalant significantly reduces cortical infarct volume in in vivo experiments, improves the metabolic and electrophysiological status of the ischemic penumbra region, and reduces the size of the lesion on magnetic resonance images in the acute phase after middle cerebral artery occlusion in rats.Pinokalant is a potential SARS-CoV-2 protease inhibitor for the study of stroke.

    价 格：￥电议型 号：T70540产 地：中国大陆

  • T70418TLN-232；化合物 TLN-232TLN-232

    TLN-232, also known as CAP-232, is a synthetic cyclic heptapeptide with potential antineoplastic activity. Pyruvate kinase (PK) inhibitor TLN-232 targets pyruvate kinase M2 (M2PK), which may disrupt tumor cell anaerobic glycolysis. M2PK is a dimeric isoform of PK and the predominant PK isoform found in tumor cells.

    价 格：￥电议型 号：T70418产 地：中国大陆

  • T69822Ritlecitinib tosylate；化合物 Ritlecitinib tosylateRitlecitinib tosylate

    Ritlecitinib, also known as PF-06651600, is a potent and selective JAK3 inhibitor. PF-06651600 is a potent and low clearance compound with demonstrated in vivo efficacy. The favorable efficacy and safety profile of this JAK3-specific inhibitor PF-06651600 led to its evaluation in several human clinical studies. JAK3 was among the first of the JAKs targeted for therapeutic intervention due to the strong validation provided by human SCID patients displaying JAK3 deficiencies.

    价 格：￥电议型 号：T69822产 地：中国大陆

  • T69115Nutlin-1；化合物 Nutlin-1Nutlin-1

    Nutlin-1 is a p53-MDM2 binding inhibitor, p-Glycoprotein (p-gp) transport substrate, and antitumor agent.

    价 格：￥电议型 号：T69115产 地：中国大陆

  • T69114Nutlin-2；化合物 Nutlin-2Nutlin-2

    Nutlin-2 is a potent and selective p53-MDM2 binding inhibitor.

    价 格：￥电议型 号：T69114产 地：中国大陆

  • T68582Tonantzitlolone；化合物 TonantzitloloneTonantzitlolone

    Tonantzitlolone is a natural agonist of tprc1/4/5 channels, also acting as a dual pkcα and pkcθ activator, inducing an insulin resistant phenotype by inhibiting irs1 and the pi3k/akt pathway, activating the heat shock factor 1 (hsf1) transcription factor driving glucose dependency

    价 格：￥电议型 号：T68582产 地：中国大陆

  • T68388TLS-IN-5；化合物 TLS-IN-5TLS-IN-5

    TLS-IN-5, also known as Rev1-?IN-?5, is the first small molecule inhibitor of translesion synthesis (TLS) that target Rev1-CT.

    价 格：￥电议型 号：T68388产 地：中国大陆

  • T674793,5-Dimethoxycinnamic acid, predominantly trans；化合物 3,5-Dimethoxycinnamic acid, predominantly trans3

    3,5-Dimethoxycinnamic acid, predominantly trans is a useful organic compound for research related to life sciences. The catalog number is T67479 and the CAS number is 16909-11-8.

    价 格：￥电议型 号：T67479产 地：中国大陆

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