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T83823Sp-Uridine-5’-O-(1-thiotriphosphate) sodium；化合物 Sp-Uridine-5’-O-(1-thiotriphosphate) sodiumSp-UTP-α-
Sp-Uridine-5´-O-(1-thiotriphosphate) (Sp-UTP-α-S) acts as a nucleotide agonist for purinergic Y2 (P2Y2) and P2Y4 receptors, efficiently inducing inositol phosphate accumulation in 1321N1 astrocytoma cells that express these receptors, with half-maximal effective concentrations (EC50s) of 14 ?M and 81 ?M, respectively.
价 格：￥电议型 号：T83823产 地：中国大陆
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T83822Rp-Uridine-5’-O-(1-thiotriphosphate) sodium；化合物 Rp-Uridine-5’-O-(1-thiotriphosphate) sodiumRp-UTP-α-
Rp-Uridine-5´-O-(1-thiotriphosphate) (Rp-UTP-α-S) serves as a nucleotide agonist for purinergic P2Y2 and P2Y4 receptors, effectively inducing inositol phosphate accumulation within 1321N1 astrocytoma cells that express either P2Y2 or P2Y4 receptors, with EC50 values of 5.4 and 27 ?M, respectively.
价 格：￥电议型 号：T83822产 地：中国大陆
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T83818Isoguanosine-5’-O-triphosphate sodium；化合物 Isoguanosine-5’-O-triphosphate sodium2-Hydroxyadenosine 5’
Isoguanosine-5´-O-triphosphate, an isomer of guanosine 5´-triphosphate (GTP) and a phosphorylated derivative of crotonoside, does not promote microtubule assembly like GTP. At a concentration of 2 mM, it hampers transcription and triggers T to C mutations in reverse transcriptase assays. This compound aids in assessing the substrate specificity of both phosphofructokinase and mutT homolog 1 (MTH1).
价 格：￥电议型 号：T83818产 地：中国大陆
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T83817Isoguanosine-5’-O-diphosphate sodium；化合物 Isoguanosine-5’-O-diphosphate sodiumisoGDP；isoGDP
Isoguanosine-5´-O-diphosphate (isoGDP), an isomer of GDP and a phosphorylated variant of crotonoside, acts as a mitochondrial ATPase inhibitor, demonstrating effectiveness at a concentration of 3 ?M (IC50 = 3 ?M).
价 格：￥电议型 号：T83817产 地：中国大陆
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T83816Cytidine-5’-O-(2-thiodiphosphate) sodium；化合物 Cytidine-5’-O-(2-thiodiphosphate) sodiumCDP-β-S；CDP-β-S
Cytidine-5’-O-(2-thiodiphosphate) (CDP-β-S), a non-hydrolyzable derivative of CDP exhibiting antioxidant activity, effectively scavenges free radicals as evidenced by its performance in the Trolox equivalent absorbance capacity (TEAC) assay at concentrations between 5 and 20 ?M.
价 格：￥电议型 号：T83816产 地：中国大陆
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T838156-Chloropurine riboside-5’-triphosphate sodium；化合物 6-Chloropurine riboside-5’-triphosphate sodium6-c
6-Chloropurine riboside-5´-triphosphate serves as both an inhibitor and an activator in biochemical processes. It inhibits the RNA triphosphatase mRNA-capping enzyme subunit β (Cet1; IC50 = 2 ?M for the GTPase activity of the S. cerevisiae enzyme), proving its efficacy against the enzyme responsible for the capping of mRNA molecules. Additionally, it acts as a phosphorylated derivative of 6-chloropurine riboside. This compound also activates the E. coli enzyme aspartate carbamoyltransferas
价 格：￥电议型 号：T83815产 地：中国大陆
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T838148-Bromoguanosine-5’-O-triphosphate sodium；化合物 8-Bromoguanosine-5’-O-triphosphate sodium8-bromo GTP；8
8-Bromoguanosine-5´-O-triphosphate, a derivative of guanosine 5´-triphosphate (GTP) - the energy substrate for protein synthesis and gluconeogenesis, acts as an inhibitor of the E. coli GTPase FtsZ with an inhibition constant (Ki) of 31.8 ?M. Furthermore, at a concentration of 500 ?M, it facilitates the assembly of porcine brain microtubules in a cell-free assay.
价 格：￥电议型 号：T83814产 地：中国大陆
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T83808Sp-Adenosine-5’-O-(1-thiotriphosphate) sodium；化合物 Sp-Adenosine-5’-O-(1-thiotriphosphate) sodiumSp-AT
Sp-Adenosine-5´-O-(1-thiotriphosphate) (Sp-ATP-α-S), an isomer of the ATP-α-S sulfur-containing nucleotide derivative and a purinergic P2Y1 receptor agonist, effectively increases calcium mobilization in HEK293 cells harboring the P2Y1 receptor with an EC50 of 9.4 nM for the human receptor. It also inhibits ADP-induced human isolated platelet aggregation with a Ki value of 4 μM and prompts relaxation in carbamoylcholine-tightened guinea pig taenia coli, achieving an EC50 of 426 nM.
价 格：￥电议型 号：T83808产 地：中国大陆
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T83807Rp-Adenosine-5’-O-(1-thiotriphosphate) sodium；化合物 Rp-Adenosine-5’-O-(1-thiotriphosphate) sodiumRp-AT
Rp-Adenosine-5´-O-(1-thiotriphosphate) (Rp-ATP-α-S), a sulfur-containing nucleotide derivative isomer and a purinergic P2Y1 receptor agonist, promotes calcium mobilization in HEK293 cells expressing the human P2Y1 receptor (EC50 = 75 nM). This compound exhibits binding affinity to washed isolated human platelets (Ki = 156 nM) and attenuates ADP-induced aggregation in human platelet-rich plasma (PRP; pA2 = 4.74), as well as inhibits cAMP production triggered by prostaglandin E1 (PGE1) in hu
价 格：￥电议型 号：T83807产 地：中国大陆
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T83806Sp-Adenosine-5’-O-(1-thiodiphosphate) sodium；化合物 Sp-Adenosine-5’-O-(1-thiodiphosphate) sodiumSp-ADP-
Sp-Adenosine-5’-O-(1-thiodiphosphate) (Sp-ADP-α-S), an isomer of the sulfur-containing nucleotide derivative ADP-α-S, functions as an inhibitor of phosphorylase kinase with an inhibition constant (Ki) of 0.53 ?M. This compound also promotes aggregation of isolated human platelets with an effective concentration (EC50) of 20 ?M and induces relaxation in carbamoylcholine-precontracted guinea pig taenia coli with an EC50 of 58.9 ?M.
价 格：￥电议型 号：T83806产 地：中国大陆
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T83805Rp-Adenosine-5’-O-(1-thiodiphosphate) sodium；化合物 Rp-Adenosine-5’-O-(1-thiodiphosphate) sodiumRp-ADP-
Rp-Adenosine-5´-O-(1-thiodiphosphate) (Rp-ADP-α-S), a sulfur-containing isomer of the nucleotide derivative ADP-α-S, acts as an inhibitor of phosphorylase kinase with an inhibition constant (Ki) of 0.53 ?M. This compound also induces aggregation in isolated human platelets with an effective concentration (EC50) of 20 ?M and promotes relaxation in guinea pig taenia coli that has been precontracted with carbamoylcholine, with an EC50 of 58.9 ?M.
价 格：￥电议型 号：T83805产 地：中国大陆
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T837897-Deazaadenosine-5’-O-diphosphate sodium；化合物 7-Deazaadenosine-5’-O-diphosphate sodium7-CH-ADP|||Tube
7-Deazaadenosine-5´-O-diphosphate, a modified nucleotide and metabolite of tubercidin, is generated through phosphorylation of tubercidin and further undergoes phosphorylation to become the active metabolite 7-deazaadenosine-5´-O-triphosphate.
价 格：￥电议型 号：T83789产 地：中国大陆
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T837868-Chloroadenosine-5’-triphosphate sodium；化合物 8-Chloroadenosine-5’-triphosphate sodium8-chloro ATP；8-
8-Chloroadenosine-5’-triphosphate (8-chloro ATP), a potent metabolite of the anticancer agent 8-chloro cyclic AMP (cAMP) and a nucleotide derivative, is produced through the biotransformation of 8-chloro cAMP into 8-chloroadenosine, followed by mono- and diphosphate intermediates. Accumulating for up to 12 hours after the administration of 8-chloro cAMP or 8-chloroadenosine, 8-chloro ATP inhibits cell growth, diminishes endogenous ATP levels, and reduces RNA synthesis without affecting DNA synth
价 格：￥电议型 号：T83786产 地：中国大陆
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T837852-Chloroadenosine-5’-O-diphosphate sodium；化合物 2-Chloroadenosine-5’-O-diphosphate sodium2-chloro ADP；
2-Chloroadenosine-5´-O-diphosphate, a purine nucleotide adenosine 5´diphosphate (ADP) derivative, demonstrates multiple biological activities. It promotes aggregation and inhibits cyclic AMP (cAMP) production, triggered by prostaglandin E2 (PGE2), in a concentration-dependent manner within isolated human platelet-rich plasma. Additionally, this compound facilitates the relaxation of precontracted isolated guinea pig taenia coli strips (pD2 = 6.74) and reduces arterial blood pressure
价 格：￥电议型 号：T83785产 地：中国大陆
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T837785-(3-Aminoallyl)uridine-5’-O-triphosphate sodium；化合物 5-(3-Aminoallyl)uridine-5’-O-triphosphate sodiu
Aminoallyl-UTP (5-(3-Aminoallyl)uridine-5´-O-triphosphate) is an amine-modified nucleotide utilized in affinity-tagged UTP synthesis. Its incorporation into complementary RNA (cRNA) and bacterial transfer-messenger RNA (tmRNA) enables the creation of fluorescently labeled probes for microarrays.
价 格：￥电议型 号：T83778产 地：中国大陆
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T834721,N6-Ethenoadenosine 5’-monophosphate sodium；化合物 1,N6-Ethenoadenosine 5’-monophosphate sodium1,N6-ε-
1,N6-Ethenoadenosine 5´-monophosphate sodium (1,N6-Etheno-AMP sodium), a fluorescent analog of adenosine 5´-monophosphate (AMP), serves as an effective probe for AMP-related systems due to its detectability at low concentrations. It is characterized by an excitation wavelength range of 250-300 nm and emits at 415 nm [1] [2].
价 格：￥电议型 号：T83472产 地：中国大陆
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T834211-Palmitoyl-sn-glycerol 3-phosphate；化合物 1-Palmitoyl-sn-glycerol 3-phosphate1-P-GPA；1-P-GPA
1-Palmitoyl-sn-glycerol 3-phosphate (1-P-GPA), an endogenous metabolite, is utilized in the research of non-alcoholic fatty liver disease [1].
价 格：￥电议型 号：T83421产 地：中国大陆
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T832965-Azacytidine 5′-triphosphate；化合物 5-Azacytidine 5′-triphosphate5-Azacytidine 5′-triphosphate
5-Azacytidine 5′-triphosphate (5-aza-CMP), a cytidine analog, selectively inhibits the incorporation of [^3H]CTP into RNA during the DNA-dependent RNA polymerase reaction, while not affecting the incorporation of [^3H]UTP [1].
价 格：￥电议型 号：T83296产 地：中国大陆
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T832955-Azacytidine 5′-triphosphate sodium；化合物 5-Azacytidine 5′-triphosphate sodium5-Azacytidine 5′-tripho
5-Azacytidine 5´-triphosphate sodium, a cytidine analog, selectively inhibits the incorporation of [3 H]CTP into RNA by DNA-dependent RNA polymerase, without affecting the incorporation of [3 H]UTP [1].
价 格：￥电议型 号：T83295产 地：中国大陆
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T832706-Azauridine triphosphate；化合物 6-Azauridine triphosphate6-Azauridine 5′-triphosphate；6-Azauridine 5′-
6-Azauridine triphosphate (6-Azauridine 5′-triphosphate), a nucleotide analog akin to uridine triphosphate, facilitates the study of RNA synthesis mechanisms and transcription regulation [1].
价 格：￥电议型 号：T83270产 地：中国大陆
